Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
EUC1
Systematic Name
YMR111C
Strain
S288c
Description
Sequence-specific DNA binding protein; binds to a sequence motif associated with distinct genomic hotspots of non-H2B protein ubiquitylation (ub-hotspots); interacts with Slx5p to recruit the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex to ub-hotspots; deletion prevents ub-hotspot formation and exacerbates heat sensitivity of cells deficient in Rpd3L histone deacetylase complex members; forms nuclear foci upon DNA replication stress
External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden
Promoter Sequence
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>EUC1 YMR111C
CAGGACGTAGCCACCGTATGAGAAGCTTTGAAACATCCAGTGATAAAAAAATCTTGACTT
TATTTATATATATGTATATTGGACATTTTAAAAACTTGATTTAAGTCGCTCATTGCGGCG
GCTTTTATATTTTGAAAGTAATCGAATGAGTACGAAAATCTGACTTGGACAGTATGCAGG
CCCTCATCTTAGCGGTTTTTTGACCCAGTCGTTAGATCTGCTAATTCGATTCAAATCTTC
TCATCAAGCCAGAGGCGCGCTTATTAGAAGGACGCTATCAAATCCAAATGAACAACGATG
CAGGTTCTCAATACGAAGAGTGAAACGAAACAAGAAAACGAAACAATGCAGCCACCATAT
ATACAAGAACGTCTTAAGTCATTAAATGATATAGAGACCCAGTTATGCTCCATGTTGCAG
GAGGCGTCTCAAGTCACGTTCATATTTGGTGAACTAAAAAGAGGTAATGAATCAGTGAAA
CCCCAATTCGAAAATCATGTCAAACAGTTTTACGAACGACTAGATAAATCAACCACACAG
CTACGCAAGGAGATACAGTTGTTGGATGAGAACGTTGGAACACGACTACTGCCCATCAAT
GTCAACAAGAAGGCCCTAGGCCAAGACACAGAAAAAATGGAAGAACAATTGGATTTATTG
TCGGCTATATTAGATCCTTCGAAATCCAAGTAAACCTTAATTAGGACTAGAACACTTTTG
TATCAAGTACAAATGTATAATTATATAAACATCACAGGGATATCATATTCCATATGATGA
TATAGCATTTACTTTACTTCAACCAGTATTGTCTAAAGAGAACGAGTTTAGTATTAGTAA
AAAAATTAAAAAAAGGAAGCGTACTTGAAACTCAAACACAAACGAGAGTACAAAGGGCAT
TGCTAGCTTAAAATATTTAACAATCAACTTCGTCTTTTGCCAGAAGACTACATTTTGTGC
CATCGAGAAGTTAGTCCAGGAGTCAACACATTAATTAAAC
Chr coordinates
Chr XIII from 493792-492404