Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SPT21
Systematic Name
YMR179W
Strain
S288c
Description
Protein with a role in transcriptional silencing; required for normal transcription at several loci including HTA2-HTB2 and HHF2-HHT2, but not required at the other histone loci; binds with Spt10p to histone gene promoters during S phase; localizes to nuclear foci that become diffuse upon DNA replication stress
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>SPT21 YMR179W
ATGTCTGAACTCTCTCAAATGACATTGAAGATCCTTTACACATTGGATAATGGATCCAAT
GGTAGTTATTTAGCCCGCTCAAGGGCTCCAAAACAGGTAAGAGTTGCTAATATTCCTAGT
CCATTCCCGACAGATTCGAATGAGCAAACGGAGTTGCGAATTGGCGCCATCCATTTGAAG
ACTATACTGCATGAAATATACTTAAATTCACCTGAAGTGTTAGACCATGACACTTTAAAA
GATGGATATGATTATAACTTGTATTATCGTGACATATGTGAAGTGGATGAGCCATTAGTA
AGCCTTGGTCTTCTTTCCGGGCTTCGAAAAAAGTTTCATAAGAATAGCCCCTACCAGTAT
ACAGAAAACAATATTGGTGAAGAAGAAAGTGAAGAGAGAGATGAGGTAACTGAAGAAGAG
TATGAAGATGAATCTTTTATAGTTACTGGAAGGGTATGCTCGAATGTTTCCGCTTTACTA
CGAAGATCATATAGCAACATCTCGAATAAAAAGGGAAGGGTCGTAAACAACCAAATTCCG
GAAGAAACTTTGGAGGTTAAACTAAGATTCACAAAAGTTATAACCAATTTAAGGACGTCT
GGTAACAATACTACAAATTCTCGGATATCGTGTCTTCAAATGCCGTCTTCTTTACCATCA
GCAACACTTCCGTTTACCCCAAAATCGCAATCTCTTTTCAAGACAAACCAAATAAAAAAT
TCAAGGAATGCAAGGACCACGATAACAATAAATAATACTAATAGCGGGACTGTGGGAAGA
AGACAGACGAATCCTATGCCTGCTCCAAAAGCTGTCAGAACTCAGTCTTTACCCATCTGG
AATCTTAAACCAAATATAGCGAATACTGGTTTCCCAAGAAATTCAATTGCGCACAAAATC
TACTTAGCAGATAGAAAAACAGAAGCCAATCAACAAAACAACCAGCATCAAAACATAGCT
TACGAAATAAATACTTTGCAAAACGATAATACTATTCAGAGGACCAAGATCGATGATTCG
GTAAGCAAGAGGTTCGATTTTATGCTCAACAAAAGAAAGTCTACGAAAAAAGTGTCACCT
GGTATAGCAACGATAGCAAAAAAACCAGCTTCAATAAACATAAATCCAAAGCAACCGCCG
AAGACTAGTGGTGAAAAAAAAGCAAATGATAAGCAAACGATTGTCAAAGTTAAGAATTCG
AATTCCAAAAATTCGGCTAAGTCTACACAAGCAGGATGTAGGCGATCATCAGTGATAGAA
CATTTAAATGATCATGACGATTCAATTTTAAGTGACATTCTATCGGAACCAGGCATTGAA
GGGCAGAAATTGCAGCAAAAACAAAAGGGGCGTAAGATATCTTTAACTAGTGAAAATGAT
AAAGAAAATATTCCACCCCAAAGCATAACTAGTAAAGAGAACAAGCTTGAAGGTGACTTG
GATTTTAACGCTGAGTTCCCCATGAGTGACTTTTCGGATGTAGTATTTAAAGATGAGATG
GGATGGTTTTCCAATTTCAATTGCAATTTTTTTGAATCACCAACTTCTGCAAGTGCATCA
CAACTCAATCAGCAAAATTTGAAGCCTTCTATAACACTCAACGATCCAAACACCTGTAAC
ACCATTGCTCTCGAAAATGAAGATGTCAGTGAATTGGAAACAGCGCAAAATAATAAAATA
TCTTTGCCTAGCGATGTTGACAAAACCTCCCCAATAGACTCGTTGTCTATACCTTTAATT
GAACTTACACATTCAAGCTCGACAACAAACATGCAGCGTATATCCATTAAAGAAGGATCG
ACACTAAATATAACAGATAGTAATAATGCCACCCCATGTGATAATGATATAAAAGATAGA
AAGGCATCTGTAATAGATTCGGACAATACAAAACCTCAGGCAGGGCTTATAAATTTCTCT
ACTCCAGCTGACCAGCCAGCTTCTGATAATAATGTTACAGCTTCGAAAAAGCTTACTAGC
ATGCTGGAAACTCAGCAAAGTAAGAGATCTCATGAAGAAGTTTTGGATGAAGAGGAAGAG
GAGGAAGCCCTCAAAAAGCAAAAGGCAATACCGTCTTCACCATGTGGGATGTTCAATTAT
CATCAACCCATGGAATTATCTGAGGACATAGTTGAAGAAGAGCAAGGACACAATATCGGC
GATGATAATGAAAGCGATAAGACCAACGATTTATTCTCAACATTCATCCATTCAGGAATA
AGAGTAAGTCAGGTAGTAACAAGTCCCATCGGTGAATTTCAGTCAATAAAACACTGA
Promoter Sequence
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>SPT21 YMR179W
CAAAAGGCACAAACGTCAAAAATTATTATGTGTGTGATGACTTGTGGGTACCTATTTGTT
CTATATCTCACAAAATGTATATACTACCCGGTATCCCTCAACTATTTGCAAGGATGCTGA
AAGCGTTCACTCCCACGTTGAAAAAAATATATAATTTGGACAAGGATCCACGTGAGTATG
TTCGTTATTTTGTCAGAACACACCTAACTGAGTCTCAAATTTCTAAAGAGCTAAAGTTGA
TTCAGGATGAATCAACAAAAGTTTCAGAAGCCATTAAAATAGGCTCATACCCACATTTTG
GTATGGGATTCAATACAGTTAGTATTTTGGGTGAAAAGAAAGACGATTCATATCTGAAGA
GTATTGTCAATAGAGTTGTTAATAACCTCGAGGGAGAAGTAATTTCTTCTGAACTTGAAA
ACAAGTTCTCGAACCAGGAGAGCTGAATACCCGAGTATTTAGAACTATGTATAGATATAG
ATTTTTTTTTTGGGAGCAAAGTCATCTCAGTCATCGCCGGTAGTTGCGCTTTCTTCTCAA
CAAAAAAGTACACTGCTCGTGGTAGAAAGGTACCTTGAAAAATTAAAGATCACATTGCTA
CTGTTAGAGCTTCAATCGCTAAAGTAAACATTTGAAAAATGCATATCCGAAAGGACCAAA
CCAGCAAAAGGTATATAATTCATTCAATAGATACAACTGCTCCATGAAAGGAAAAACCTT
CATTTACGGTCGCGTTTTTTTTCGTGATATAAAAAAGGTAAAAAAAACGCGTCGCGTTAG
AAAAAAGGTGTGTGTGAAGAGAAAGACCCATTGAATGGAGAGTTCGGTTCTTGGGAATTG
CACTGAGCCGTGGTGAGTTTGTTGCTTTACTACATCTCTTCTTTTATAAGCAACGCTTAA
GCTGAACCTAGTCAACACACATAACTGAAGTCAATTTGACCAGGTGCAACTGAAACCTGG
ATTGGAATTGGTATTCACTTGAACAAAAGACTCTGGTAAA
Chr coordinates
Chr XIII from 619858-622134