Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SGS1 Systematic Name
YMR190C Strain
S288c Description
RecQ family nucleolar DNA helicase; role in genome integrity maintenance, chromosome synapsis, meiotic joint molecule/crossover formation; stimulates activity of Top3p; rapidly lost in response to rapamycin in Rrd1p-dependent manner; forms nuclear foci upon DNA replication stress; yeast SGS1 complements mutations in human homolog BLM implicated in Bloom syndrome; also similar to human WRN implicated in Werner syndrome; human BLM and WRN can each complement yeast null mutant External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>SGS1 YMR190C
ATGGTGACGAAGCCGTCACATAACTTAAGAAGGGAGCACAAATGGTTAAAGGAAACGGCG
ACTTTACAGGAAGACAAAGATTTCGTATTCCAGGCTATCCAAAAGCACATCGCGAACAAA
AGGCCTAAGACAAATTCGCCACCAACAACGCCATCCAAAGATGAATGTGGACCAGGAACA
ACAAACTTTATAACCAGCATTCCTGCATCTGGACCAACGAATACTGCTACGAAACAACAT
GAAGTCATGCAAACTTTGTCGAACGATACAGAATGGCTCTCGTACACTGCCACATCGAAT
CAATATGCTGACGTACCCATGGTTGATATACCAGCCAGCACAAGTGTTGTATCGAACCCG
AGGACGCCCAATGGCTCGAAAACTCACAATTTCAATACTTTTCGACCGCACATGGCTAGT
TCTCTTGTCGAAAATGACAGTAGCAGAAATCTAGGTAGTAGAAATAACAATAAAAGCGTA
ATCGATAATTCAAGTATAGGCAAACAGCTCGAAAATGATATAAAATTAGAGGTGATCCGC
CTTCAAGGCTCCCTAATTATGGCATTGAAAGAGCAATCGAAATTATTGCTACAGAAGTGT
AGTATTATCGAATCCACATCATTGTCAGAGGACGCTAAAAGGCTACAGTTAAGTAGGGAT
ATACGGCCTCAGTTATCAAATATGTCGATACGAATAGATAGTCTGGAAAAGGAGATCATA
AAAGCCAAAAAAGATGGAATGTCAAAAGATCAAAGTAAAGGTCGCAGTCAAGTTTCTTCA
CAAGATGATAATATCATATCAAGCATTCTGCCCAGCCCCTTGGAATACAATACATCTTCC
AGGAATTCAAACCTGACAAGTACTACTGCGACTACCGTCACTAAGGCATTAGCCATCACT
GGTGCGAAGCAAAATATTACTAATAACACCGGTAAGAATAGCAATAATGATAGTAATAAC
GATGATTTGATTCAAGTCCTGGATGATGAGGATGATATAGACTGTGACCCTCCTGTAATA
TTGAAGGAGGGGGCTCCACATTCTCCCGCATTCCCGCATCTCCACATGACGTCAGAAGAA
CAAGATGAACTTACAAGAAGGAGAAATATGCGTTCAAGAGAACCAGTCAACTACAGAATA
CCTGATAGGGATGATCCTTTTGACTATGTTATGGGTAAATCTTTGAGGGACGATTATCCG
GATGTCGAAAGAGAAGAAGATGAGTTAACAATGGAGGCAGAAGATGATGCCCATTCCAGC
TACATGACTACTAGAGATGAAGAAAAAGAAGAAAACGAATTACTAAATCAAAGCGATTTT
GATTTTGTGGTAAACGACGACCTAGACCCAACTCAAGACACAGATTATCATGATAATATG
GATGTTAGTGCAAATATTCAGGAAAGTTCTCAAGAAGGTGACACTAGGTCCACAATTACC
TTGTCGCAAAATAAAAATGTTCAAGTTATTTTATCATCTCCCACAGCACAGAGCGTTCCC
TCAAATGGCCAAAATCAAATAGGCGTGGAGCATATTGACTTGTTGGAAGATGATCTGGAA
AAGGACGCAATTTTGGATGATAGCATGAGTTTCTCCTTTGGCCGTCAACACATGCCCATG
TCTCATTCTGATCTAGAGTTGATAGACAGCGAAAAAGAAAATGAGGATTTTGAAGAAGAT
AATAACAATAACGGTATCGAGTACCTATCAGATAGCGATTTAGAAAGATTTGACGAAGAA
AGAGAGAATAGAACCCAAGTAGCAGATATCCAGGAACTAGACAATGACCTGAAAATAATA
ACAGAAAGGAAGCTTACAGGTGACAATGAACACCCACCACCATCTTGGTCTCCCAAAATA
AAAAGGGAGAAATCCAGTGTTAGTCAAAAGGATGAGGAAGACGATTTTGATGACGATTTT
TCATTAAGTGATATAGTGAGTAAATCCAATTTATCTTCTAAGACGAATGGTCCAACCTAT
CCTTGGTCTGATGAAGTTTTATATCGTTTACATGAAGTCTTTAAACTGCCTGGTTTTAGA
CCTAACCAACTAGAGGCTGTAAATGCAACTTTGCAAGGTAAGGATGTTTTTGTTCTTATG
CCAACAGGGGGTGGTAAATCTCTTTGCTATCAACTTCCTGCAGTGGTGAAATCGGGTAAA
ACACATGGTACTACTATTGTCATCTCTCCGCTAATTTCCCTGATGCAAGATCAAGTGGAA
CATTTATTGAATAAAAATATTAAGGCGAGCATGTTCAGTTCGAGGGGTACTGCCGAGCAA
AGACGACAAACTTTCAATTTATTTATTAATGGATTATTGGATTTAGTTTACATATCTCCT
GAGATGATCAGTGCCTCAGAACAATGCAAGAGAGCTATCAGTAGATTATACGCAGACGGT
AAGTTGGCTCGTATTGTTGTAGATGAAGCACATTGTGTTTCTAACTGGGGCCACGATTTC
AGGCCTGATTATAAAGAATTAAAATTTTTCAAAAGAGAATACCCTGATATTCCAATGATT
GCTTTAACTGCAACTGCAAGTGAACAAGTCAGAATGGACATCATTCACAATTTAGAACTA
AAGGAACCTGTTTTCCTAAAACAAAGTTTTAATAGAACAAATTTGTATTACGAAGTAAAC
AAGAAGACCAAAAATACCATTTTTGAAATCTGTGATGCGGTTAAATCTAGGTTCAAAAAT
CAAACGGGTATAATATATTGCCACTCCAAGAAATCATGCGAGCAAACATCAGCCCAAATG
CAAAGAAATGGCATCAAGTGTGCATATTACCATGCAGGCATGGAGCCTGATGAAAGATTA
AGTGTACAGAAGGCATGGCAGGCGGATGAGATACAAGTCATTTGTGCTACTGTTGCTTTC
GGAATGGGTATTGATAAACCTGATGTGAGATTTGTTTACCACTTTACCGTTCCCCGAACA
TTAGAAGGCTATTATCAAGAAACCGGCCGTGCTGGAAGAGATGGGAACTATTCATATTGT
ATTACCTACTTTTCATTCAGGGACATTAGAACCATGCAGACAATGATCCAGAAGGATAAG
AACTTAGACAGAGAGAATAAGGAAAAACATCTGAATAAATTACAGCAAGTAATGGCATAC
TGTGACAACGTTACTGACTGCAGAAGAAAGTTAGTTTTATCTTATTTCAATGAGGATTTT
GACTCCAAACTGTGTCATAAAAACTGTGATAATTGTAGAAATAGCGCCAACGTGATAAAC
GAGGAAAGGGATGTTACAGAACCTGCCAAGAAGATTGTAAAATTAGTGGAAAGTATCCAA
AATGAAAGAGTCACAATAATTTATTGCCAAGATGTCTTTAAAGGTTCGAGAAGCTCCAAA
ATTGTTCAGGCTAACCATGACACCTTAGAGGAGCATGGTATTGGTAAATCCATGCAAAAA
TCAGAAATCGAAAGGATTTTCTTCCATTTGATTACGATCCGAGTTTTACAAGAGTATTCA
ATAATGAACAATAGCGGTTTTGCTTCAAGCTATGTGAAAGTTGGTCCCAATGCTAAGAAA
TTGCTGACTGGAAAAATGGAGATAAAGATGCAATTTACAATATCAGCACCAAACTCCCGT
CCCTCGACATCTTCTAGCTTTCAAGCAAATGAAGATAATATACCAGTTATCGCGCAGAAA
TCAACAACCATTGGAGGAAATGTGGCTGCTAATCCACCGCGCTTTATAAGTGCGAAGGAA
CACCTAAGATCGTATACATACGGCGGTTCGACCATGGGTAGCTCACATCCGATCACTTTG
AAAAACACAAGCGATTTACGCTCGACACAAGAACTTAATAATCTGCGAATGACATACGAA
CGTCTGAGGGAATTATCTTTAAATTTAGGAAATAGAATGGTTCCTCCAGTTGGGAACTTT
ATGCCTGACAGTATTTTAAAAAAGATGGCAGCAATATTACCAATGAATGATTCGGCTTTT
GCAACTTTAGGCACAGTGGAGGACAAATATCGCCGAAGGTTCAAGTACTTTAAAGCCACG
ATAGCAGATCTTAGCAAAAAGAGATCAAGCGAGGATCATGAAAAATACGACACAATACTA
AATGATGAATTTGTGAACAGGGCCGCGGCTTCCAGCAATGGGATTGCCCAAAGTACTGGA
ACAAAATCTAAGTTTTTTGGCGCCAATTTAAACGAAGCCAAAGAAAATGAACAAATTATC
AATCAAATCAGACAAAGCCAATTACCCAAAAATACCACAAGCAGCAAATCAGGTACAAGG
TCCATCAGTAAGTCGTCCAAGAAGTCTGCTAATGGGAGACGAGGTTTTAGAAATTACCGA
GGTCACTACAGAGGAAGAAAGTGA Promoter Sequence
Download FASTA
>SGS1 YMR190C
CTTAAATAGTTCTAAATTACGAATGAAATTGATATCCTTTTGAGATAACTTCTTAAGGGC
AACTGGTTGGACGTGATCCTGTTTAGAGGTAACATTAGACGCATTCTGATAAGCTTTGCA
GGAATTAGAGTGGGAGCACTGATTTAATCCGCCTAGTGAGTTGAAAAAACACCTCAAAGA
TATAGTCATGTTATTCACGGCTTCTTGGGTAAATTTGATACTGGAAGTCGAATAAGCTCT
CTGCCCTAATAATCTCTTTGATGTAGTCATATTCCAGTTGGTAAAAAGGCCCCTTGGGGC
TCCTTTGGGCACTCTGGGAAAAGAAGCAAATTTACTGACATTGGGAACAGGTCTGAAATG
GTCAAACCTTGCGATTCCTCTCCTCGTGAGAGGAGATACCGTTAAACCACTTGCCCTCCT
AAAAGCTGTAGAAGCCTCAAATAGGCTCTTCCACCAAGTGACAAAAATATTGCGATTATA
TTGGTGGGAAAAATTCCCATGGCTCAAACTGATCAGCGTTCGGTCCAGAGACTTCGTGAT
CTGCCTGAGGTGGACCCGTGACATTCGCAGCCACATGCTCCAGTTATTACCACCGACAGC
CATATTTCGTGTTGGTGCTCTTCTATTGTGAAAGAACCACTTTAGATCATGAAATGCGAA
ATGTGAAGGAAGAGAAGCTTCTCTCCACATGTCCTTTATATTTATATAGTTCAGCCGTGC
GTTTCGAAGTGGATTGCCCGGCTTCGGCTGCCAGGATTTGTTTATGCTTTTGCAATGCAC
ATATAACAAGAAACTCGAGCCTGATCTAAAAGCTGATATACGGATCAATAGAGGGCACTT
AGCAGGCTGGGTGATCATTGGTGATACATTTCGGATTTGTGGCTTTACCGTTTAGTTTGT
TTTTATCAGCCAGCTTGGAGTCATTGGCTAGAGGAAAGGAAAAAATACAGATTATTGTTG
TATATATTTAAAAAATCATACACGTACACACAAGGCGGTA
Chr coordinates
Chr XIII from 645258-640915
