Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
EFR3
Systematic Name
YMR212C
Strain
S288c
Description
Protein required for Stt4-containing PI kinase complex localization; required for Stt4-containing phosphoinositide (PI) kinase patch assembly at plasma membrane; recruited to plasma membrane via conserved basic patch near N-terminus; exhibits synthetic lethal genetic interactions with PHO85; mutations in human homolog EFR3A implicated in autism spectrum disorders
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>EFR3 YMR212C
ATGCAGTTGTCTATGCGGATGATGTTCACACCAAAACATCAGAAACTGGTCAATCAATGT
TATCCTACGGGAAGGACCACAGATAAGAAGCCTAAATCTTCGGAAACTTCATATTTGCTA
TATTACGTTAACTCGAGGCGTAGTAAATTGGAGAAAGTTAGCACTTACCTGATTAAGCGT
TCCACTTCCGACTTGAACCATCGGCGCATAGGGAACATAGCCGTTACATTGGATTTAATG
AACAAAATTGTGTTGCATTGTAAGGAGAATTTGAATGTATTTGTTAAAGATTTTTTGTAC
ATTATGAACAAAGTTCTTTCCAACAACAATTTTAACAATGATGTATCTGTTGTTGAATTA
ATAGAACTGGCATTTAGTAGTATATGCCAGAACTTGGACGACGTCTTGTGTAACGGTGAC
ATGGAATTCGTCCAGTTATACCAGAACTTTGTTGATCTTTTTTTTAAAATAGTTACTGAA
AGAATTCATAATGATGACATGCTTCTGAAATGCTGTATTGATATATCAAACACAAATAGT
GTTTCAAGCAACCCACAACTAAACCACTTTGTTTCCAAGTCTGTTGCCTATACTATTTCA
AAGTTCCAAGAGAGAAATCCGAAATTTAAAACTTTGTCGCTGGAAGCAGCTCTGGAGAGC
AATTTAGGAAAAAGGCTAAGTCGAACACAAACTCGTACAATTGGGTTAGATAAGGCCGCC
GAAGATAATCATGACCTTTCAGTAAAAGCATTGCAATCCTATTTTAACACAACTGAGACA
GACAAATTGAATTTGTCTATTCGTACTCTGTTGCGCTGTCTGCAAAGTACACCTAATAAG
GAACTGCTAGAGTTTGTATGCAATGGTATACCTGTTCAGTTACGATATATTGTTATACTT
CTTTTGGTCAGACAACTAAGCGACAAGGATAAAAATGTAAATCCAATTGTTTCCTTGAAA
TTGATGTCGTCATTACTTGTTTCAGATGTCAGTATAGTGGGGTTGAGTGTTCTTGATATA
ATGAGAAAGCTTTTAAATTTCCAGTTGAAAAATGCAACTAATAAAGAAGTTGTGGCACAG
TCTTGTATCACCATGACAGACCTTAACCATAAAACTTATTACGCTGAACAGACCTCAGAT
ATGTTATATGAACTACTATTGAAATTGAAAAGTGACACCGTCAAGGATGTTGAAAAGAAT
GCAGTTGTGGAAGATATTGATTTCCTCGTTGAACATATTACGCAGCCAAGTATCAGTTTG
GAATTATTCATCGACTTGGCGCATTACATGAAAAACCACATTATATGTTTATTTAACATT
GTTGAAACTGAGGTTCCAAGCAGCATTCTCTTTTCAAAACTGTACTCATTATTACGTGAA
CTGGATTCACATGGTGTGCAAAAAGAAATGATGGAAGAGATCTTTGACAAGTATGGAAAA
ATGGCACTATTATCCGGTTTGAATTATTTTCTAGAGAACGTTTCTGAGCCTGAGTATACC
TATTATTCGTACCATTTACAAGCAGCTAACTTTTTAAAACTCAATGACTACAAGTCACAA
ACTGAGTACAAAATGCAAACTAGAACTTTGTTTACCAAGGAAGATTTATTGTCATACTAT
TCTGATACTGGATCAAATAAATACAGCAAGAAGGGGGCGCAGATTTTATTGTCTCGTGAT
AATCAAATTTCTACTTCTGATTTACTGTCGGACTCTCAAGTTCGTACTACACCTCTGGAG
TACAAGAATGTCCCTAATGCTATTTTTTCAAATGGGAAAGCAGTGTATGATAACAACGAT
TTTGCGGCCAAGCAAAATAAATTCGACAACAGCATAGATGACAATATAGAAGAAGCTAAC
GATACTGTAATTTCTGATGCTAATGCAAAAGGTAGTATCTATAGGTTTGTTGCTGAGGAC
GCAAGATCATGGAAAACAATGAGAGCCACCGCACCAAAAGTTAGCGATTTGAAAAAAACT
ATGAATGAAAAGAATATTCCAAATAATATGAAAAGAGATGGCTCTTTTCGGGGTTCTCAA
TCAGTGAAATCTCGTGTCACTAATATCACATTTTTATTAAATGAATTGAAAACTTTTTCA
GATGACGCGAATAAAATCAAAGATCCTGATGAGGAGAATATTGTTGGCTTGGATAAAATC
GACGTTGCTAGATCAAATTCTCTGCGACTTGCACCAATATCTAGTCTTTCTGATCGCAGT
AGCATTGGAAATAGAAAATCCTTTTTGCAAAAAACAGCAACTGGTGAAAATCAAAACGAT
GACTTTAAAGACGCAAATGAAGATTTACATTCTTTAAGTTCAAGAGGTAAAATTTTCTCC
TCCACTTGA
Promoter Sequence
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>EFR3 YMR212C
TTGTTCATATACTATATCTTCATTGTAATCAATGTCGGTGCCGTATTTTTTTTTCGGTTT
CTTAATGGCAACATTAATTCCTGCTTGCTTTAGCTCACGCCTCTTTTGTAGTTCAGCAAT
GCGTTTTGATTCTTCGAGCATCCGCTCTCTAATCTTTCTTGTAGCCTTCTTACCTTGGGT
ATTTAACAGACGAGCCCTAGCTTCAGCAAGCATTTCCTTTTCCTCATCTTCCAAATCACC
ATTATCTGGTCTAGCCATTTGAGTTTCAGCGTTAGGATTAATATCCCCGGCTTTCAAGTC
AGTAACTCCTGTACTTAACGCAGCCCCTCCACTGTCTTCACTTTCTAATAGCCTATTATA
TCTTTCGACGCAGACCTGTGCAGGCCTGGCCATCATATCAGCTATGGTCCTCCACTGATT
AGGCAGCTCTCTTGCAAGATCTAGAAGTTGGGCATCCTCCTCCTTCGAGAACTCTGTAAA
ATTCAACTTTGGATTTAAATATTCATTCCACCTTAATTCACTCTGCCTGGCAGTCTTTTT
CTGCAAAAGGGATGCTACTTTGCTCCACTGATGAGTTCCGTATTTTTGTACAGCCGCTTT
AAGAATCTGATCCTCCACATTGGTCCATACACCGCCTTTCACGTATATTGGTACGGGGGG
CATCTTGAAATGCTAGTATAGTCCTCTTAGAAATGTTTTGCTTTTTTTCTTTACTATCTT
CCTGAGTCGCATATGCTTTTTTGTCATAATAGTTCATAGCATTAATTTTTCATTAAACTT
CAACCCCGGCCAAAGGAAGAGGAAGAAAATTTTGTTCGAACTACTAGGAAGGTAATGGTT
TTGTTGAAAAAGCCAGGCAGCCAGGATAAATTGAAAGTATTGTGAGCAACCCCGCTATTG
GAGTAGTATTAATTCAGTGGCAGACTGTATATTGAACCCAGATCATTCGCTCTATTATTC
ATCTTTCGTTCATTTTCAATTGTTCTGAAAGTGGTTTGCG
Chr coordinates
Chr XIII from 693043-690695