Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
GUA1
Systematic Name
YMR217W
Strain
S288c
Description
GMP synthase; highly conserved enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation; reduction-of-function mutation gua1-G388D causes changes in cellular guanine nucleotide pools, defects in general protein synthesis, and impaired translation of GCN4 mRNA
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>GUA1 YMR217W
ATGGCTGCCGGTGAACAAGTTTCTAACATGTTTGACACTATCTTAGTGTTAGACTTTGGT
TCTCAATACTCTCATTTGATTACCAGAAGATTAAGAGAGTTTAACATCTATGCTGAGATG
TTGCCATGCACTCAGAAGATCTCTGAGTTGGGCTGGACTCCAAAGGGTGTCATTCTTTCT
GGTGGTCCATATTCCGTATACGCTGAAGACGCTCCACACGTAGACCATGCTATCTTTGAT
TTGAACGTTCCAATCCTGGGTATCTGTTACGGTATGCAAGAATTGGCTTGGATTAATGGT
AAACAAGTTGGTCGTGGTGACAAGAGAGAGTACGGTCCTGCCACTTTGAAGGTGATTGAC
GATTCCAACTCTCTATTCAAAGGTATGAACGACTCTACTGTCTGGATGTCTCACGGTGAT
AAATTGCACGGCTTGCCAACTGGTTACAAGACCATTGCCACCTCCGATAACTCCCCATAC
TGTGGTATTGTCCACGAAACTAAGCCAATCTATGGTATTCAATTCCACCCAGAAGTTACA
CATTCTACCCAAGGTAAGACTCTTTTGAAAAACTTCGCCGTTGATTTGTGTCACGCTAAG
CAAAACTGGACTATGGAAAACTTTATCGACACTGAAATAAACAGAATCAGAAAACTGGTC
GGTCCAACTGCTGAAGTCATTGGTGCTGTTTCCGGTGGTGTTGATTCTACTGTTGCATCC
AAATTGATGACAGAAGCCATCGGTGATAGATTCCATGCCATCTTGGTCGATAACGGTGTT
TTGAGATTAAATGAAGCTGCTAACGTTAAAAAGACCCTTGTCGAAGGTTTAGGTATCAAC
TTGATGGTTGTCGATGCTTCCGAAGAATTTTTAAGTAAATTGAAGGGTGTCACTGACCCA
GAAAAGAAGAGAAAGATTATTGGTAACACATTTATCCACGTCTTTGAAAGAGAAGCTGAA
AAAATTAAGCCAAAAGATGGTAAGGAGATTCAATTCCTGTTACAAGGTACTCTTTATCCA
GATGTCATCGAATCCATTTCTTTCAAAGGTCCTTCTCAAACCATTAAAACTCATCACAAC
GTCGGTGGTTTACTAGAGAACATGAAATTAAAGCTAATTGAACCATTGAGAGAACTGTTC
AAAGACGAAGTCAGGCATCTAGGTGAATTATTAGGAATCCCTCATGATCTAGTCTGGAGA
CACCCTTTCCCTGGTCCAGGTATTGCTATTCGTGTTCTAGGTGAAGTTACTAAGGAACAA
GTCGAAATAGCAAGAAAAGCTGACAACATTTACATTGAAGAAATCAAGAAGGCCGGCTTA
TACAACCAAATTTCCCAAGCCTTTGCCTGTTTGTTGCCCGTTAAATCCGTTGGTGTTATG
GGTGACCAAAGAACCTATGATCAAGTTATTGCTTTGAGGGCCATTGAAACTACTGATTTC
ATGACTGCTGACTGGTTCCCATTCGAACACAGTTTCTTGAAGAAAGTCGCCTCAAGAATT
GTCAATGAAGTCGATGGGGTTGCTAGGGTCACTTACGATATAACTTCCAAACCTCCTGCA
ACTGTTGAATGGGAATGA
Promoter Sequence
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>GUA1 YMR217W
TCGAGGAAGTATCCTCTTGTACAGTACCGTTGGCACTAGAGGATGACTTGGAAGTCTGCA
AGGCCAAAGACAGTTTAGACTTCGTTGGAGCAGGCGCCTTCTTCATCATGTTATAATCCC
TTTGAAAGAAATTCTTCTTCGCTTCCTGCGAGCTTGTTGCTTCCTCACATGAAATGCTCG
CATCCGTACTAGTGTCAGCCAAATGAGCGCTTTTAGTCACAAACCCAGGATAGTTAATTG
ATGAACCCATTAATGTCTACACTTCTTCTTTACTCTATCTCTTCAACCTCAAAAGGGGGT
GTCTATTTATACCAAAAAACACAATTATTTCTCAGCGCCAGGTGATCTAACAATTTTGAA
TCAGTTTTCCAATCTCTATTAACTTGCCAGCTACAAATAGATCCCTCTATATCCTGTGAC
TTCTCTATAGCTCTTTCATAGCCCACACTCATTGTTTATTCTCTTTCAAATAAATAACGA
CGATAAGATTTAGAAAAATAGAAAAAGAAATTAGAAAAAAATCCGGAAATAATATAGGCT
CGTCCGTAACGATTTAATATCACGTGGATAGTGATATAATTATGAGGTGTTGCCAAATAG
AACCTTTAATTATGTTTAACAGCGAAAAAACAAGGTTGTCAAGTAGCCGACTCATTTCTT
CGTGACGTTGGTGACAGGAATATGCTTTCATCCTCTCGCTCCCCTACAATGGCTTCGGTT
CCCGACATTTTGACTCTTTTCATGCCGTCATTTCTTTTTCTTGCTTGCAGGAAATGAAAA
TTTTTTTTTTCTTTGGCGATGAGCATCGAGAAAAAATATTTCTTTTTTTTATCATTTTTT
CAGTTTCATTTTCATTTCACAGTTATAAAACATTAGTTGAGTTATAGTTTCGGTCACGGT
AGTCTCTAATTAGCTTGCGTTCGTTGTAGTTTAACTTCCCTGGGTCATTTGGTAGGTAAT
ATCTATATTCTAAAATAAACTAACGACATCAATATTCACA
Chr coordinates
Chr XIII from 701790-703367