Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
RKR1 Systematic Name
YMR247C Alias
LTN1 Strain
S288c Description
RING domain E3 ubiquitin ligase; involved in ubiquitin-mediated degradation of non-stop proteins and translationally stalled ER membrane proteins; component of ribosome-bound RQC (ribosome quality control) complex; degrades products of mRNAs lacking a termination codon regardless of a poly(A) tail; functional connections to chromatin modification; homolog of mouse Listerin, mutations in which reported to cause neurodegeneration External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA View Seq
Sequence hidden Promoter Sequence
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>RKR1 YMR247C
GTTGTCACTCATTATCCTATTGCATTATCAAGTCGTGCGTTCCACCCCCATTAAATTTGA
TGGCAGCTTTTAAATCTTTACCTTTATGCCATATTTCTACGTCGTATATGTAATAAGATG
GATGCTAGACTATAGGGGGTAGGTGGTTCCTCTTCCGACATGTAGAGAATGTGGATTTTG
ATGTAATTGTTGGGATTCCATTGTGATTAAGGCTATAATATTAGGTATGTAGATATACTA
GAAGTTCTCCTCGAGGATTTAGGAATCCATAAAAGGGAATCTGCAATTCTACACAATTCT
ATAAATATTATTATCATCGTTTTATATGTTAATATTCATTGATCCTATTACATTATCAAT
CCTTGCGTTTCAGCTTCCACTAATTTAGATGACTATTTCTCATCATTTGCGTCATCTTCT
AACACCGTATATGATAATATACTAGTAACGTAAATACTAGTTAGTAGATGATAGTTGATT
TTTATTCCAACACGACAATCATGAGTAATTACTTGATAGTGGATAGTAAGTTTTGATAGA
CACTTCCATTTTAAACTGATTTCACTTTTTACAGTGGCTAGAAATTACAATAAGAAATGG
GCGTGTGGCGTAGTCGGTAGCGCGCTCCCTTAGCATGGGAGAGGTCTCCGGTTCGATTCC
GGACTCGTCCAAATTTTTTGCTACTTTGCAATTAGTGTAACTTCATATTTAAAATTATAG
TTAATCAAGAACAGAATATCGTCACAATGCTCTTTAAATGTTACGTACTTCTTACCTCCA
GCTTGACTATATACTTGTCAATTCGAGTTAACCCAGATTATGCCCCAACATGGAAAACTG
AAAAATATTGATGAAGCGAGGAAAAAAAACGTCATAGGAAAAATTCAAATGTTGCAACTT
CAGATGGTTTTCTTCAATATATACAATACTGAAGAAGTCCTTCTTAATAGTTCAAATCTG
CTAAGCCATCAAAAAAAGTTCAAGCAATAGTTGGTTCTTA
Chr coordinates
Chr XIII from 768039-763351
