Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name RKR1
Systematic Name YMR247C
Alias LTN1
Strain S288c
Description RING domain E3 ubiquitin ligase; involved in ubiquitin-mediated degradation of non-stop proteins and translationally stalled ER membrane proteins; component of ribosome-bound RQC (ribosome quality control) complex; degrades products of mRNAs lacking a termination codon regardless of a poly(A) tail; functional connections to chromatin modification; homolog of mouse Listerin, mutations in which reported to cause neurodegeneration
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>RKR1 YMR247C
GTTGTCACTCATTATCCTATTGCATTATCAAGTCGTGCGTTCCACCCCCATTAAATTTGA
TGGCAGCTTTTAAATCTTTACCTTTATGCCATATTTCTACGTCGTATATGTAATAAGATG
GATGCTAGACTATAGGGGGTAGGTGGTTCCTCTTCCGACATGTAGAGAATGTGGATTTTG
ATGTAATTGTTGGGATTCCATTGTGATTAAGGCTATAATATTAGGTATGTAGATATACTA
GAAGTTCTCCTCGAGGATTTAGGAATCCATAAAAGGGAATCTGCAATTCTACACAATTCT
ATAAATATTATTATCATCGTTTTATATGTTAATATTCATTGATCCTATTACATTATCAAT
CCTTGCGTTTCAGCTTCCACTAATTTAGATGACTATTTCTCATCATTTGCGTCATCTTCT
AACACCGTATATGATAATATACTAGTAACGTAAATACTAGTTAGTAGATGATAGTTGATT
TTTATTCCAACACGACAATCATGAGTAATTACTTGATAGTGGATAGTAAGTTTTGATAGA
CACTTCCATTTTAAACTGATTTCACTTTTTACAGTGGCTAGAAATTACAATAAGAAATGG
GCGTGTGGCGTAGTCGGTAGCGCGCTCCCTTAGCATGGGAGAGGTCTCCGGTTCGATTCC
GGACTCGTCCAAATTTTTTGCTACTTTGCAATTAGTGTAACTTCATATTTAAAATTATAG
TTAATCAAGAACAGAATATCGTCACAATGCTCTTTAAATGTTACGTACTTCTTACCTCCA
GCTTGACTATATACTTGTCAATTCGAGTTAACCCAGATTATGCCCCAACATGGAAAACTG
AAAAATATTGATGAAGCGAGGAAAAAAAACGTCATAGGAAAAATTCAAATGTTGCAACTT
CAGATGGTTTTCTTCAATATATACAATACTGAAGAAGTCCTTCTTAATAGTTCAAATCTG
CTAAGCCATCAAAAAAAGTTCAAGCAATAGTTGGTTCTTA
Chr coordinates Chr XIII from 768039-763351
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