Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
PPA2
Systematic Name
YMR267W
Alias
IPP2
Strain
S288c
Description
Mitochondrial inorganic pyrophosphatase; required for mitochondrial function and possibly involved in energy generation from inorganic pyrophosphate; human ortholog, PPA2, functionally complements the null mutant; mutations in human PPA2 cause a mitochondrial disease resulting in sudden unexpected cardiac arrest in infants
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>PPA2 YMR267W
ATGAATTTATTACGAATGAATGCTTTAACAAGCAAGGCTAGGTCAATAGAACGGTTAAAA
CAAACATTGAATATTTTATCCATTCGTAATCATAGACAATTCAGCACCATTCAACAAGGC
AGCAAATATACCCTCGGGTTTAAGAAATACTTGACATTATTAAATGGAGAGGTTGGTTCT
TTTTTCCATGATGTCCCTTTAGATTTGAATGAACATGAAAAGACCGTAAATATGATTGTT
GAAGTACCAAGATGGACAACTGGAAAATTTGAAATATCCAAAGAACTTAGGTTCAATCCG
ATCGTTCAAGATACGAAGAATGGCAAGCTTAGGTTCGTGAACAATATCTTTCCCTATCAC
GGCTATATACACAACTATGGTGCTATTCCCCAAACATGGGAAGATCCCACAATTGAACAT
AAACTGGGGAAGTGTGACGTGGCTTTGAAAGGTGACAATGATCCTCTTGATTGTTGCGAA
ATCGGTTCGGATGTTTTGGAAATGGGTTCCATTAAAAAGGTCAAGGTATTAGGATCACTC
GCTTTAATTGATGATGGAGAATTGGATTGGAAGGTCATAGTGATCGACGTAAATGATCCT
TTATCCTCTAAAATAGATGACTTGGAAAAAATTGAGGAGTACTTTCCTGGGATTCTAGAT
ACGACTAGGGAGTGGTTTAGAAAGTATAAAGTTCCAGCAGGGAAGCCATTAAATAGTTTC
GCCTTTCATGAACAGTATCAAAATTCCAATAAAACCATCCAAACTATAAAGAAATGTCAC
AATTCGTGGAAAAACCTCATTTCAGGATCACTCCAGGAGAAGTATGACAACCTGCCTAAT
ACAGAAAGGGCTGGTAATGGTGTCACACTTGAAGATAGTGTTAAACCCCCTTCTCAAATA
CCGCCTGAGGTGCAAAAATGGTATTACGTTTAA
Promoter Sequence
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>PPA2 YMR267W
ACAAGAGGAGTGAATCAGTCACTGAGCAACAAGTTGAAAATAGCATATTTAGTGAAAATA
CATTCGAATATCAATTCAACCCAGCAAATGAAGCCAATGCAGATGGGCACGCTATAAATG
CAGAAAATTTAATTGAGGACGTGCCATTATTAGCAGATGGTGATACAATGAAAATTCCTC
CGGCTCCATGGTGGAAGAGATTCTTAAAACCTCACATTTACTACTCCTATAAGGCTGTAA
AGAGCAGACTGCCAGAAATATATGGTTTGGTTGATCCTGATGAAAGAGTCAATGATTTCG
ATATCTCTCATGCTTACGATTATCCAGCTGTTAGTGCACAATGCCCCGAATTGTGGATTC
CTCGCGATCCTTTTGGATTTTCCAAATTGTTGATTTCAGACGTTTCTGGCGTTGTTGAAA
TGAACGATGAAAATGCTACCATCGATGAGAATTTGAAATTTACTCTGCGTGACGTACCAC
CACCATATAATGATGTTAAAGACGAAGCAAATGGTGAAGCAAATGGCGAATTTGACACAG
CTAGTAAGGAAAATAATCCATTTGCGGACCCAAAGTATAAGGAAGAAGAGAGTCGTTCGG
CAGTCTAAAGGTTAAACATTATCAGAAATTATCTATTCCTATTTGTTTAGCTGTTATCCT
CTGATGGTTGAATTGTAATTTTACTAAGAAAAGGAGAGGAAAAGGACGTGCATATATTCT
TTTAATACATTTAAAATATGATTCTAATCATTTCTTATATAATAGTGTATAGTCTAATCA
TTCATCGTGTATAGTAACCCTTTTTGTTTTTTTTTATGCAAAGTTTTTTTGTTTTTGGCA
ATCTATGAGGTTTGAATATTGGATAAAAGGAACTCCGCACAGTAATACGGAGCAGTCAGC
TAATTTAACCAGCACTAATAGGGAGTACATTCAATTGGAAACTTTGATTCGCTTGTATGC
GTGAAAAGCAAATTCCCTTCTAGAGAAGTTACTGAAAAAC
Chr coordinates
Chr XIII from 801772-802704