Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
FKH2
Systematic Name
YNL068C
Strain
S288c
Description
Forkhead family transcription factor; rate-limiting activator of replication origins; evolutionarily conserved regulator of lifespan; binds multiple chromosomal elements with distinct specificities, cell cycle dynamics; positively regulates transcriptional elongation; facilitates clustering, activation of early-firing replication origins; negative role in chromatin silencing at HML and HMR; major role in expression of G2/M phase genes; relocalizes to cytosol under hypoxia
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>FKH2 YNL068C
ATGTCCAGCAGCAATTTTAACGAGATGAACGAACTAAATATGACTCAAACAAATTATGGC
AGCACAAAATATACCGCTCAGCATCATCAAGGTGTAATAAATGCCATCATCTCTTCACTG
ACAGCCCCAGATCAGCCAACTACCGTATCATTACAATATTCCAACGACAAGAACATGGCG
ACGGAAATACAAGCTTATGCTAAACTCTCCGGACCAAACTGGACCTATTATGTGAAGGAT
TTGGAAGTTTCTATTGGTAGAAATACTGATCCCTTAAACAGTGCACTACAGGAAAATTCA
GATGGTGTAAAAAACTCATATAGAGTGAATATTGATCTCGGACCTGCCAAAGTCGTTTCT
AGAAAGCACGCCATAATAAAATACAACATGAATATCGGCGGTTGGGAATTGCACATATTG
GGCCGTAACGGCGCTAAAGTAAACTTTCAAAGGACTCATAATGGACCCAACAATCCTCCC
ATTCGATTATCTTCCGGAACCCTGCTAGACATAGGAGGAACACAAATGATGTTTATCCTG
CCCGACAGTGACCCGGTTGTTGCTCCTATTTGTATAGAACACCTGATGCCTAATTTAATA
AACATGTTCGGATTGGAAGGCAACAACAACCCCCTGCTAAGAGACATTATAAAACAGTCT
AATTATGCTAAGCAAAGGCAATTAACCTCTAATCAACAAATCAAAGGGTTTAAGCTTTAT
GGAAGTGGTGGCAATGCTCCTTTTGGTAGCGGAGCGAACTTGGGCCCTAGCGAACAAGGC
ATCTTCAACAACAATAATAATAGTAAGAACAAGAATGGCTACTTTACGTCCATAAACCCA
AACTATACAGCATCTACAACAACAAGCAATACCATCAATCCACAAGCGGCTTCTCCACAG
GGTCCTCCAAATACCATCATCGCTGCAAATTTTGTAGATTCATACAAGTCATCAAATGCC
TATCCTCAAGCTTTGGATTTTACTTCGGACCTATCCCATGACGAAAACAGGAACGTTAAA
CCACCTCATTCATACGCAACTATGATAACACAGGCCATACTGTCGTCGCCGGAGGGAGTT
ATTTCACTAGCCGATATCTACAAGTATATTTCTTCCAATTATGCATACTACAGGTTTGCT
AAATCCGGTTGGCAAAACTCCATTAGGCATAATTTATCATTAAATAAGGCGTTTGAAAAG
GTTCCGAGAAGACCCAATGAGCCGGGCAAAGGTATGAAATGGAGAATTAGCGAATCTTAT
CAGCAAGAATTTCTAAACAAGTGGAATACCGGAAAAGTGGGGAAAATCAGGCGGGGATCC
TCAGTAGCAAGGCAACTACAGTTACATATGGCAAAATTCAACAGTTTACCCATGGAAATG
GACTATAGGTTATCGCTTAACATGGCTCAACCCCCTAAACGACAACTACAATCTCACAAT
GTGCTAGAACCATCCAACAATAACATCATAGAAGGGTTCGTACAACATGTCCCATCCAAA
GGTAACCTTCCTGCATCGCAACAATCACAGCCCCCTGTGTCACATCAAAATCAGTCACAG
CAGCCGCCACCACAGGAACAACGTCAAGAGATTCAATTTACCTTCGCGGATACCCAAAAT
CGAAATATAGCGTTAGCAAGACCTATCAAGACGCCACAATTGCAAGCTCCCAATTCAAAT
GCTAACTTAAATCAAAACAATATGAAAGAATACAAAGAGTCACTTCATCCGCCTGCAATA
TCAATATCACAAATGAATAGGCAATCTCCAAACAACGCTCTAGTCTCGTTCACTAATGCA
TGTGCTAATTCCAAAATAATAAACAACATCAGCGATAGCGCCGACAAATCGACAAACAAT
AACGGCGGTACCAAAATGAATCTACCCGCCATATCTACTTCTTCACTTGATGAAAATGGT
AATTTGGAGCCGACAACTACCACGTCTTCCGGTAATTCTAACTCAGTTCCGCAAACTGGA
ACAACAACTTCCTCATTGGCAGCGAACAGTCTACGCCTTTCTCAACCATATGACACGCTA
TTACGATCTCCTACTAAGGCATTTCATATTACTGCGATGGAAGCATATACACCAGAAAGA
GGAAGCGCTAATAGGGCTAGGTCACCTCTTCATAGTAATAGCAACAATACTAATAATAAC
GGCGCAAATAATTCTAATTTACAGACTAGCGGAATGGAAAACAAACAAACAGGTCTAGTA
TTGGATTCTAATGTCTTGAAAAGCATGGAATCAAACAATGATAATAGACGGCTGACACCA
TCAACAAGTAAATCGCAGAATGTCAAAAGTTCTCCAGGTGTATGGAATTTATTGCAGTTT
AGCTCAACAAACAACACTCCTGCCGCAGATAGCGGAGGCAACAAGAGAGGATTTTCCATA
AATCCGGACATTAAAGCCAAAGAAAACGAGAATGCTACTTCAGAAAAAGATTCGGACTCT
AACTCAAATGATCTGGAAACTAAAGATATTAATTCTTCACCTTTGAAAAACCAAGGTGGT
AGCACCGCCAATGCCAAGGAACTAATACTAGATACGGATGGTGCAAAGATCAGTATTATC
AACAACTAA
Promoter Sequence
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>FKH2 YNL068C
CTGTAAGTAAATCGATTGCAAAATTGGTTCCTACCGCTACGATATCACACACTTGTCTTC
TTAAAAGAGGAGCAGTAAATCCAAAATTTGCCTGGCATCAATAGTCGTCTTAAAAATGTC
TAGAGGAACTACCTCTGTTATCTCTTCTTTTTGTTACTGACATACTAATTAATTTTTACA
TAATTGCTGTCCTCCTTCCCCTTCTATTTGCGAATTAGAAGTGATGAAAAAAGAGCTAAA
CATAAAGAAAAAAAACTTCCTTCGGCTGGTCCAAAAGGGTCCAATAGCAGAAAGTAAAAA
GCTATTTTGAAACTATAGAACCTCAAGAACATTAACATTTGAGTCGGATCATGTCAACTG
TAAGAACTGAATATTAATTCAACATATTTTAATAATTTGTGTCATATGTATCTTGCAACA
GGCTTTCAAAAATTTGCTGCCTGTTGGGTACAGGCTGTTTTTTATTGATTACGCTTTATG
CTTATCCCTTAAGCTGCAACATTTTGATGGCCTCTTCTTCCTGTCTCTTTCTGTGCCATA
TAATCGTTCCCTTAGCATTGATGATGACTTATGCCGGACCCCGCCCCAGAACCCTTCGCA
CAACATTACCGAAAATCTTCGATTTCGCTCATTAAAAGAGGGAAAAAAAATTCGCTCGCC
CTGTGCCATTTGGATTTTCTAGGTAAATTAGTAAATAAAGAAAAAAAATGCCAATGGTTC
CGCATTTCTAAAGGTAAACAAAAAAGTGACATTCATAGGATCACTATATTTCTGTAAAAC
TTAAAACACTATAGAGCAGTCCTTTTCCACTGAATTGAACCGCTCAATAATCAAGATCAT
ACTAAGGAACAAAAGGCTAAAAACACTTCAAAGCCAATCTTCCCGATTCCCTCGCATAAG
TGATCATTGCTAGAAAAAAAAAAAAAAAACAGTACGATACACATAAATATTGGTGTGCTC
CCTCCGTTTCCTTTATTGAAACTTTATCAATGCGCAAGAA
Chr coordinates
Chr XIV from 498289-495701