Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
LEU4 Systematic Name
YNL104C Strain
S288c Description
Alpha-isopropylmalate synthase (2-isopropylmalate synthase); the main isozyme responsible for the first step in the leucine biosynthesis pathway; LEU4 has a paralog, LEU9, that arose from the whole genome duplication External sources
Open in SGD
Open in KEGG
Gene Sequence
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>LEU4 YNL104C
ATGGTTAAAGAGAGTATTATTGCTCTTGCTGAGCATGCGGCCTCCAGAGCCTCAAGAGTT
ATTCCTCCAGTGAAGCTAGCCTATAAAAATATGCTTAAGGACCCTTCCTCCAAGTACAAG
CCATTTAACGCTCCAAAGCTATCTAATAGAAAGTGGCCGGATAACCGGATCACGAGGGCT
CCTCGTTGGTTATCAACAGATTTGAGAGATGGTAACCAATCTCTGCCGGATCCCATGTCA
GTGGAACAAAAGAAAGAATACTTTCACAAGCTGGTCAATATTGGGTTCAAAGAAATCGAG
GTTTCCTTCCCCTCTGCATCTCAAACAGATTTCGACTTCACTAGATATGCTGTAGAAAAC
GCCCCAGACGATGTTAGTATTCAATGTCTTGTCCAATCTAGAGAACACTTGATTAAGAGA
ACGGTGGAAGCATTAACAGGTGCTAAAAAGGCTACTATACATACTTACTTGGCAACAAGT
GATATGTTCCGTGAAATTGTTTTTAATATGTCTAGAGAGGAAGCTATTTCCAAGGCAGTA
GAGGCCACCAAACTAGTTAGGAAACTAACTAAGGATGACCCTTCCCAACAAGCCACTCGT
TGGTCCTATGAGTTTTCCCCCGAATGTTTCAGTGATACTCCAGGTGAATTTGCTGTAGAA
ATTTGCGAAGCTGTTAAGAAGGCTTGGGAACCTACCGAGGAAAATCCAATCATTTTCAAC
TTACCTGCTACCGTAGAAGTTGCCTCTCCAAATGTTTATGCTGATCAGATTGAATACTTC
GCTACCCATATTACTGAGCGTGAGAAGGTTTGCATCTCTACACATTGTCACAATGACCGT
GGTTGCGGTGTCGCCGCCACAGAGTTAGGTATGCTTGCAGGTGCCGACCGTGTAGAAGGA
TGTCTCTTTGGTAATGGTGAACGTACAGGTAATGTGGACTTGGTTACTGTTGCTATGAAT
ATGTATACCCAAGGTGTTTCTCCTAATTTGGATTTCTCTGACTTGACCTCTGTCCTAGAT
GTGGTTGAGCGTTGTAATAAGATCCCAGTATCGCAAAGAGCACCATACGGCGGTGACTTG
GTCGTTTGTGCCTTTTCCGGTTCTCACCAAGACGCCATTAAGAAGGGTTTCAACTTACAA
AACAAGAAGCGTGCTCAAGGTGAAACTCAATGGAGAATCCCATACTTGCCATTGGATCCA
AAGGACATTGGCCGTGATTACGAAGCTGTCATCAGAGTCAACTCTCAGTCTGGTAAAGGT
GGTGCCGCTTGGGTTATTTTGAGATCTTTGGGTTTGGATCTACCAAGAAACATGCAAATC
GAATTTTCTAGCGCCGTTCAAGACCATGCTGACTCCTTGGGTAGAGAACTAAAATCAGAT
GAGATTTCCAAGTTATTCAAAGAGGCTTACAACTACAATGACGAACAGTACCAAGCTATT
AGTTTAGTCAATTATAATGTTGAAAAATTCGGCACTGAACGTAGAGTGTTCACTGGTCAA
GTCAAAGTAGGCGACCAGATCGTCGATATTGAAGGTACAGGTAATGGTCCAATCTCTTCT
TTGGTCGACGCCCTATCAAACTTGTTGAACGTGAGATTTGCCGTAGCAAACTACACAGAG
CATTCTCTAGGTTCTGGTTCTTCTACGCAAGCTGCTTCTTACATCCATCTATCGTATAGG
CGTAATGCCGACAACGAAAAGGCCTACAAATGGGGTGTAGGTGTCTCCGAAGATGTCGGT
GATTCTTCAGTGAGAGCCATCTTTGCCACCATTAACAATATTATCCATTCTGGTGATGTG
TCCATTCCATCTTTGGCCGAGGTCGAAGGTAAGAATGCTGCGGCATCTGGCTCTGCATAA Promoter Sequence
Download FASTA
>LEU4 YNL104C
TGGGACTGCTCCTGCTTCATCGTTCACAGTGGAAAAAAAGGAATAAAAGTGCTTATCAGA
AGTGCGCTTTATTGACGAGAGTCTGTCTAAACAGTTGACGGACAGGCAAGAAGACCTTCA
GGAGTTGACTAATATATGAAATGATGTGCGTTCAAACAGACCGTTTCACCTGGCACAGAT
GCATGTAAACAAGGATATACGTTATTACATGCTACGGCTACATCTAGATTGGGTGGATTT
AAGTTGAACGATGAAAGAAAATTCAAGCAATATGCTTGTGTGGCCCGATGACACACAATA
GCATGTGCGACGAGACACCAGCTGTGTGCCGGGTGCTACCCGCGCACGTGATTAAAAGGA
AACGGGGAAAAAGCCATAGCGGAAAAGTGCTCGAAGAAGCCTCGATAAATGAAGTAAAAA
ATTCGATATTTTTCAACGACAATAAGACGTATATAAGCATCCGTATGTCCAGCGATTGAG
CTTATGCTTCTGTTCTCCGCTTTGACACTTCCACTCGGCTGTTATGACCAGCCCCAGGAT
TGCTACCGGAGCGGGACCGGCTCTGAGACAGTAGTAGGTTAGTCATCGCTCTACCGACGC
GCAGGAAAAGAAAGAAGGCCTCAGAAAAGCTGAGTTGAATGTGTGTCATACTTGGCTGAA
AAAATTGTACAGTAACGGCCAGTCACTGTCATGCGCGTGCATGTATGTGCGTGCATGTAT
GTGTGTATGTATATTTATATATATATAAGCACGGGCGCATGGGAGATGTGCGCTATGGAG
TCGCGTAGGTTCGATGTTTTCTCCTCTTGGGTCAGCCTCTCTCCTCTTTCAACGTTCTTT
CCATAATCATTTATTGGTTATTTTTCAACTTGACCAGTAAAAAGAAACTTACGTGTAAGT
GACTCAGTTCTTTCAAAGGGTATTTTTTGAAGAAAAAAAAGGATTCTCACACTAGAAGTT
TACTGTAGACTTTTTCCTTACAAAAAGACAAGGAACAATC
Chr coordinates
Chr XIV from 426754-424895
