Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
DMA2
Systematic Name
YNL116W
Alias
CHF2
Strain
S288c
Description
Ubiquitin-protein ligase (E3); controls septin dynamics and spindle position checkpoint (SPOC) with ligase Dma1p by regulating recruitment of Elm1p to bud neck; regulates levels of eIF2 subunit Gcd11p, as well as abundance, localization, and ubiquitination of Cdk inhibitory kinase Swe1p; ortholog of human RNF8, similar to human Chfr; contains FHA and RING finger domains; DMA2 has a paralog, DMA1, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden
Promoter Sequence
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>DMA2 YNL116W
TACCTGTCATCGGAGGGGTGTTCATGCCATGGGTGGTATGGCTGCGCAAATCCCTATCAA
AGACGACCCGGCAGCCAATGAAAAGGCCATGACTAAAGTCCGTAATGATAAGATTAGAGA
GCTGACAAATGGACATGATGGGTCATGGGTTGCACACCCAGCACTGGCCCCTATTTGTAA
TGAAGTTTTCATTAATATGGGAACACCAAACCAAATCTATTTCATTCCTGAAAACGTTGT
AACGGCTGCTAATCTGCTGGAAACCAAAATTCCAAATGGTGAGATTACTACCGAGGGAAT
TGTACAAAACTTGGATATCGGGTTGCAGTACATGGAAGCTTGGCTCAGAGGCTCTGGATG
TGTGCCCATCAACAACTTGATGGAAGACGCCGCCACTGCTGAAGTGTCTCGTTGTCAATT
GTATCAATGGGTGAAACACGGTGTTACTCTAAAGGACACGGGAGAAAAGGTCACCCCAGA
ATTAACCGAAAAGATTCTAAAAGAACAAGTGGAAAGACTGTCTAAGGCAAGTCCATTGGG
TGACAAGAACAAATTCGCGCTGGCCGCTAAGTATTTCTTGCCAGAAATCAGAGGCGAGAA
ATTCAGTGAATTTTTGACTACATTGTTGTACGACGAAATTGTGTCCACTAAGGCGACGCC
CACTGATTTGAGCAAATTGTGATCTCCCTTGCCCCAGTGTACACATATATAAAAATATAT
TCATGCCTATATGATTATGTATCGGAATCCAAAAACTTATCTTTATATTGCTTCGTTTCG
TAGTTAGCAATGAATCATCTTATCATGATTCCTTTTTTTGTTTTGGCCAGATTAATGTAT
CACGGTCGACGGCGAAGGCATCAACCATTGTTGTGGAATTTCAAACACAATACTTGATGA
CTCCAAACGTGGGCATATATTTTGATTTGAAAAGAAGTCGAGAAAGTATAGCAACGCATT
GTATACGTTTGAAGCTTTCAGCAAAGGATATACCGTGGAA
Chr coordinates
Chr XIV from 408341-409909