Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
NMA111 Systematic Name
YNL123W Alias
YNM3 Strain
S288c Description
Serine protease and general molecular chaperone; cleaves Roq1p, which modifies the substrate specificity of the Ubr1p Ub-ligase, promoting the stress-induced homeostatically-regulated protein degradation (SHRED) of misfolded and native ER-membrane and cytosolic proteins; chaperone activity involved in the heat stress response; promotes apoptosis through proteolysis of Bir1p; role in lipid homeostasis; mammalian Omi/HtrA2 serine protease family member External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>NMA111 YNL123W
ATGACCATATCGTTGAGCAATATAAAGAAAAGAGACCATTCTAAAATTTCCGATGGAACT
TCTGGTGAATCATCGCTTGTAAAAAGGAAACAGTTGGAAAGCGCCACCGGAGATCAAGAG
GAAGAATATACAGACCATGAAATCATTATAGAGCCGTTGCACTTTGCTAATAATAATAAC
ACTGTACTCACAGATTCAGAAAATTATCTAAGATGGCAAAATACCATCTCCAACGTTGTT
AAATCAGTGGTTTCCATTCATTTTTCACAAGTTGCGCCATTCGATTGCGATTCTGCTTTG
GTATCTGAAGCTACCGGATTTGTCGTGGATGCTAAATTAGGTATAATTCTGACCAATAGG
CACGTCGTTGGTCCTGGTCCGTTCGTAGGCTACGTAGTTTTCGATAATCATGAAGAATGC
GATGTTATACCAATTTACAGAGATCCTGTTCATGATTTTGGGTTCCTCAAATTCGATCCG
AAAAACATAAAATATTCTAAGATCAAAGCGTTAACGCTAAAACCAAGTTTGGCTAAGGTC
GGCTCAGAAATTAGAGTTGTCGGTAATGATGCCGGTGAGAAATTAAGTATCCTAGCAGGT
TTTATTAGTAGAATTGACAGGAACGCTCCAGAATATGGTGAGCTGACATACAATGACTTC
AATACAGAATATATTCAAGCTGCTGCATCTGCTTCTGGCGGTTCAAGTGGTTCTCCAGTC
GTAAATATAGATGGGTATGCTGTGGCTTTACAGGCAGGTGGCTCTACAGAGGCATCTACT
GATTTTTTTTTACCGTTAGATAGAATTCTTAGAGCGTTAATTTGCATCCAAACCAACAAA
CCTATCACACGTGGTACGATTCAAGTTCAATGGCTGCTGAAGCCTTATGACGAGTGTAGA
AGATTAGGTTTAACTTCAGAGAGAGAAAGTGAGGCTCGTGCTAAATTTCCCGAAAATATC
GGACTGTTGGTAGCAGAAACCGTTTTAAGAGAAGGCCCAGGCTATGATAAAATTAAAGAA
GGTGATACTCTAATTTCAATAAACGGTGAAACCATATCTTCTTTCATGCAAGTGGATAAA
ATTCAAGATGAAAATGTTGGGAAGGAAATCCAATTGGTTATTCAAAGGGGCGGTGTCGAA
TGTACTGTCACCTGCACTGTTGGTGATTTACATGCTATCACCCCTCATCGTTATGTAGAG
GTTTGTGGTGCGACTTTTCATGAATTATCATATCAAATGGCAAGGTTTTATGCGCTACCT
GTCAGGGGTGTATTTTTAAGTAGTGCATCAGGGTCTTTCAACTTTGATTCAAAAGAAAGA
GTGGGTTGGATTGTGGATTCTATAGACAATAAGGAAACCCCCGACTTAGATACATTTATT
GAAATTATGAAAACTATTCCAGATCGTAAGCGCGTTACTGTACGATACCACCATCTAACA
GATCAGCATTCTCCACTTGTTACTTCTATTTACATTGACCGTCATTGGTGCAATGAATTC
AGAGTTTACACAAGGAACGATACAACTGGTATTTGGGATTACAAAAATGTTGCTGATCCA
CTTCCAGCCGATGCGTTGAAACCTCGTTCGGCCAAAATTATTCCTATTCCTGTTAATAAT
GAAAAAGTTGCAAAATTGTCATCATCGTTATGTACAGTGGCTACAATGGCAGCAGTTCCA
TTGGATTCACTTTCTGCTGATATTTTAAAAACATCAGGCTTAATCATTGATGCTGAAAAA
GGTTATGTCCTAGTGTCCAGAAGGGTAGTTCCACATGATTGTCTTGATACTTTTGTCACC
ATTGCAGATTCCCTTGTAGTTCCAGCCACAGTAGAATTTCTCCATCCAACTCACAACTTC
GCTATTGTTAAATATGATCCAGAGTTAGTAAAGGCTCCACTAATCACTCCCAAGCTATCT
ACCACCAGAATGAAACGTGGTGATAAGCTTCAGTTTATAGGTTTTACCCAGAATGATAGA
ATTGTTACTTCAGAGACCACTGTCACCGATATTTCCTCTGTAAGTATTCCAAGTAATTTA
ATTCCGAGGTACCGTGCCACTAATTTAGAAGCTATATCTATCGACTGCAACGTTAGCACC
AGATGTAATTCCGGTATTTTGACAGATAATGATGGTACAGTAAGAGGTTTATGGCTTCCA
TTTTTAGGCGAAAGATTAGAAAATAAAGAAAAGGTTTATTTGATGGGATTAGATATAATG
GACTGTAGGGAAGTTATAGATATCTTAAAAAATGGCGGTAAACCAAGAGTAAGTATAGTT
GATGCTGGGTTCGGTTCAATTTCCGTTCTGCAAGCCAGAATTAGAGGTGTGCCCGAAGAA
TGGATCATGCGTATGGAACATGAATCAAATAACAGGCTACAGTTTATCACTGTTTCTAGA
GTTTCTTATACAGAAGACAAGATTCATTTAGAGACCGGTGACGTCATTTTATCTGTGAAC
GGAAAATTAGTCACTGAAATGAATGATTTGAATGGAGTTGTAAGCTCAGCTGATGGTATT
TTGCCATCAGCCATGTTAGATTTTAAAGTTGTTCGTGATGGTAATATTGTTGATTTGAAA
ATTAAAACCGTGGAAGTTCAGGAAACCGACCGTTTTGTAATATTTGCAGGTAGTATCTTA
CAAAAGCCGCATCATGCTGTTTTGCAAGCTATGGTTGATGTTCCAAAGGGTGTCTACTGT
ACATTCAGGGGAGAATCGTCACCGGCGCTCCAGTACGGTATATCTGCCACAAACTTCATA
ACTCATGTCAATGAAATTGAAACACCTGATCTAGATACATTTTTGAAAGTTGTCAAAACA
ATCCCTGATAATAGTTATTGTAAAATGAGGTTAATGACTTTCGACAATGTGCCCTTCGCT
ATTTCACTGAAAACGAATTATCATTACTTCCCTACTGCAGAATTGAAGAGGGACAACATC
ACGCACAAATGGATTGAAAAGGAATTTACCGGCAACAGCCAAAGTGAAAAATAG Promoter Sequence
Download FASTA
>NMA111 YNL123W
AAATGAAGAAACAGCAACGGCAACGAAAGAAAAGGGACAACCGCAAACTAGCCAACGATA
GTGACAATGTCAAGGTAAAGAGAGCTCGGCAGCCCAAGGCCAACAGTTTACCTAAACTGG
TACCGCCGTTGGGCATGAGCAGTAATGCTCCGATGCAACATGGGTACAAATCAAGAAACG
CACGTGAAAATATCAAGCGTGAATCCAGTGCTACCTCTAATCGGAATGGCTCCTCCCCAG
TGCCAATCACACAGCACCACCAACAACAGTTTTCTGCAAATAATTATCCCTTCCCTCAAC
AACCAAACGGTATGCCTTATCCACCATACTCACCTTTCCCTCAGCCGACTAACTTCCAGT
ATCCACCTCCACCATTTGGGCAGGCGACACCGGCCCAATTCTCCAACACTGTTCCATATG
GTAGCTTACCTCCCGCATACAACAATATGTCGCCGCCAACACAGCAGTCGTTCATGCCAA
TGACCCAAAGTCAACCGCCACTTCCATATGGCGTACCTCCCATGAATCAAATGCAAAACC
CAATGTACATCCAACCGCCACCTCAAGCACCTCCTCAGGGAAATGGTAATTTCCAACAAG
TAATGGAATTACATCAAATACTTTTGCAGCAACAGCAACAGCAACACCAGTATCAGCATC
AGCATCAGCAAGATCCAAGAACCTAGAGTCACGATTGAAATATTTAATAATAAATGCTAT
GTATCATAGATAAACTAGAAAGAGGCAAGAAAAATTTAACAAGTTTCTTAATTGAATATT
ATTTTACTGTCACTACCATTATTAGACGCCATCTCAGCGTGTGACATGATAATTTTTCTT
TTTTTCTTTTTTTTTCCTCAAGGCGATGATATGAAACTTTCAAAAAATTTATATGTAAAT
AAAAAAGTTCTACGAGGGTTTAAATACGGAAGTTTATTTAGAAGATATTTATACTCTGAA
TACACACGTAGAGTACAGTAAAGGTTTTTTAGATCTACTA
Chr coordinates
Chr XIV from 394685-397678
