S.cerevisiae - Yeastract

Locus Information

Standard Name	LTO1
Systematic Name	YNL260C
Strain	S288c
Description	Substrate-specific adaptor protein involved in apo-Rli1p maturation; subunit of the Yae1-Lto1 complex, recruiting apo-Rli1p to the CIA targeting complex, facilitating the insertion of an Fe/S cluster by the Fe-S biosynthetic machinery; deca-GX3 motif crucial for complex formation; essential for aerobic but not anaerobic growth; homolog of human ORAOV1, which is overexpressed in solid tumors; co-expression of ORAOV1 and YAE1 homolog YAE1D1 restores growth and Rli1p maturation after LTO1 depletion
External sources	Open in SGD Open in KEGG

Gene Sequence Download FASTA View Seq	Sequence hidden
Promoter Sequence Download FASTA	>LTO1 YNL260C TACAATTATTAGCGAAGGAACCAAGTTACAAAAAGATGAGAGAAAAATTCGCCACTATGG GCAAGTTTCTACCATTACATTTAAAGGAGATTATGGAGATGTTTTACAATGGGGATTTTT ATCTTTTTGCGACAGACGAACTAATCCAATGGATAGAGTTATTGTTTGCCGACACTCCCC TGCGAAGGAATGCCATTGATGATATTTACGAAATTAGAGGCACTGCTCTAGATGATTAAA AAATAATTAATCGTAGGATAGGTTACATGATCATTGCAATAGATGTACATCTTGTATTAC GTATGCGTAAGTTGTCTTTTTTTCAGTTTTCTAATAAATTTCACGTGATGCGGTAGTTTT TTTTGGGGGTGCAAAGTTGGCACATCTTGTAGTGCATTTTTGAGCTTCTTAAATGACTTG AATCATCTTAAAACATTGCAGGATGAGATTTCCAACGACACAAGAGAGAACTAGCGCAAA AGATGGCAGAGATAAAACATTATCAATTCAATGTCGTCATGACCTGCTCGGGATGTTCTG GTGCAGTCAATAAAGTTTTGACGAAATTAGAACCAGACGTTTCCAAAATAGATATATCCC TTGAAAAGCAATTAGTAGATGTATATACTACACTTCCTTACGATTTTATTTTAGAAAAGA TTAAGAAAACCGGAAAGGAAGTTAGATCTGGCAAACAATTGTGAATGAAAGTGAAGAGAA ATAGTTTTTTACTCTATTTTGTATTGTAGCTACTTAAGTAAATGATTAATATTCTCAATA GGATGCTTACGAAGAAAAAAGTCTTTTTTTATTGTTTTATTGTTTTATTCTTTGTTGGCT ATGTAGCCATTTGCCTTTTCAGTATAATCTTACTAATATAAAAATCTCAATCATGGTGAG AAATCGTTTTATAAGAAAAATGAAAAAAAACTTGTTTAAATCAAATCACTTATCATATTT GAAGAGTAAATGGAAAGTAAAGATCACTGGACAAATAAAA
Chr coordinates	Chr XIV from 156859-157347