Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
RFA2
Systematic Name
YNL312W
Alias
BUF1, RPA2, RPA32
Strain
S288c
Description
Subunit of heterotrimeric Replication Protein A (RPA); RPA is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination; RPA protects against inappropriate telomere recombination, and upon telomere uncapping, prevents cell proliferation by a checkpoint-independent pathway; in concert with Sgs1p-Top2p-Rmi1p, stimulates DNA catenation/decatenation activity of Top3p; protein abundance increases in response to DNA replication s
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>RFA2 YNL312W
ATGGCAACCTATCAACCATATAACGAATATTCATCAGTAACGGGCGGTGGCTTTGAGAAC
TCTGAGTCCCGCCCAGGTAGTGGGGAGTCGGAAACTAACACTAGAGTTAACACCTTGACA
CCTGTGACGATCAAACAAATTCTAGAGTCCAAACAGGATATTCAGGACGGCCCCTTCGTT
TCGCATAACCAAGAACTTCATCACGTTTGTTTTGTAGGTGTGGTGAGAAACATTACAGAC
CATACTGCAAATATTTTTTTAACTATTGAGGATGGAACTGGTCAAATAGAAGTGAGAAAA
TGGAGCGAAGATGCAAATGACTTGGCTGCCGGTAACGATGACTCTTCTGGTAAAGGTTAT
GGTTCGCAAGTCGCCCAACAATTTGAAATTGGCGGTTACGTAAAAGTTTTTGGTGCTTTG
AAAGAGTTTGGTGGTAAGAAAAATATACAGTATGCGGTGATTAAGCCCATAGATTCATTC
AATGAAGTGTTGACGCATCACTTGGAAGTCATCAAATGTCATTCCATAGCCAGTGGAATG
ATGAAACAACCTTTGGAGAGTGCATCCAACAACAATGGGCAATCATTATTTGTCAAGGAT
GATAACGATACATCTTCCGGCTCCAGTCCGTTACAAAGAATTCTAGAATTTTGTAAGAAG
CAATGTGAGGGCAAAGACGCTAATTCATTCGCTGTTCCCATTCCATTGATCTCGCAATCC
TTGAATTTGGATGAAACTACCGTCAGAAACTGCTGTACGACCTTGACTGACCAGGGTTTT
ATCTACCCAACTTTTGATGACAATAACTTCTTTGCCCTATGA
Promoter Sequence
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>RFA2 YNL312W
TTTTGAAATCTTCGTGAATACTCTCCGGTAATTCCTTAGTTATCGCATATGCAAGGTCAG
CAGACTGATATATTGCAGATGCAACACTAGCTTGGAACCCAGAAGGTTCTGGAATCAGTG
ACAATTGCGTCAAAAGAGCTCTTGCCCACCACCAATAAGCTACAGCTAATAATCCAGGAG
TAGACTCAGCAGAGATAATAGGTAGCGGAATTTCTTGATCCGGGGTAACATCAAATAAGC
TTTTTTGGCCGGTTATCCTTTCAAGTAATAATAGTGATAAAACCAAATACAATGGATCAT
CCATAAATTCGTAGGCAGGCTGGCCCATAATGGCTAATGAGCGGGAAAGGGCTGTATTAA
CTGCTCCTATTTCAATTCCAGTTTTGCCAAACAAACCTGAGATTGCTTTCAACCTAGCTG
CTGGGCCGGTGTAGTTATTTTGAATAAAGGTCTGTAAGAGGGCAATAGCCAAAAATAGCA
TCTCATTTTCTTGGCCCATTTTGAAAACCTCAACGTTAAGAAAGTCATTTAGAGCAGCAA
TAACACTAGATGTGGATATTTCTCCCGAAATACTAATTTTTCCCTTAAATTTGTCCACAA
ATTGCTGTACTAGCTGGTATGATTCACCACTGATGATATGTTCAGCCTTTTTCACATATG
TCTGGTCGAAAGAACCACTTTTCAGAGATTCTACTTCTGCAGACAGCAATAATTTTGCAT
GCAATAACGTCTCCATAATTTTGCAACCACTAGTTTACTTTTTGCCTGGTCTGATAGCTT
CTTTTTAGCAATTCCTTTGGCCTCGATGAGCTTCCATTTTCAATTTTCATCTTTTTTTTC
ACGATGCGAAGTTTCTTAGATAATTATCGCCATATACGAAACGCGTTAGGAAACGCGTTC
TTTCCTTTATAATAAGCAATATTATATCAACTTAAGGTGGAAGTAATGTGGCAAAATCGA
TAGCGACTATCTAGAACAGGCTAGTTTAAGCATATACATA
Chr coordinates
Chr XIV from 48287-48293,48402-49216