Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
CIT1
Systematic Name
YNR001C
Alias
CS1, LYS6
Strain
S288c
Description
Mitochondrial citrate synthase; catalyzes condensation of acetyl coenzyme A and oxaloacetate to form citrate, which is the first and rate-limiting step of the TCA cycle; transcription subject to glucose repression; CIT1 has a paralog, CIT2, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>CIT1 YNR001C
ATGTCAGCGATATTATCAACAACTAGCAAAAGTTTCTTATCAAGGGGCTCCACAAGACAA
TGTCAAAATATGCAAAAGGCTCTTTTTGCACTATTGAATGCTCGCCACTATAGTAGCGCC
TCCGAACAAACGTTGAAGGAGAGATTTGCTGAAATTATCCCAGCAAAGGCAGAAGAAATT
AAAAAATTCAAGAAAGAACACGGTAAAACCGTTATTGGTGAAGTTCTTTTGGAGCAAGCT
TATGGTGGTATGAGAGGTATTAAAGGCCTTGTTTGGGAAGGTTCCGTGTTAGACCCCGAA
GAAGGTATTAGATTTAGGGGTCGTACTATTCCAGAAATTCAAAGGGAACTACCAAAGGCT
GAGGGTAGTACAGAACCTTTGCCAGAAGCTTTATTTTGGTTGCTTTTGACTGGTGAAATA
CCTACTGACGCTCAAGTTAAAGCCCTTTCTGCTGATTTAGCTGCCAGATCAGAAATTCCA
GAGCACGTTATCCAACTTTTAGATAGCCTCCCAAAAGATCTACATCCAATGGCGCAATTT
TCTATTGCCGTGACTGCTTTAGAAAGCGAGTCTAAGTTTGCCAAAGCATATGCTCAAGGT
GTATCCAAGAAAGAATATTGGAGCTATACATTTGAAGATTCGTTAGATCTGCTGGGTAAA
TTACCTGTTATTGCTTCCAAAATTTATCGTAATGTGTTCAAGGATGGTAAAATTACTTCA
ACCGATCCTAATGCTGACTATGGTAAAAATTTGGCCCAACTTTTGGGCTACGAAAACAAG
GATTTTATTGACTTAATGAGACTATATTTAACTATTCATTCTGATCATGAAGGTGGTAAC
GTTTCTGCCCATACTACACATTTAGTGGGTTCTGCCTTATCTTCGCCATACTTATCTTTG
GCCGCTGGTTTGAATGGTTTAGCTGGCCCATTACATGGTCGTGCCAATCAAGAAGTTTTA
GAATGGCTATTTAAATTGAGAGAAGAAGTGAAAGGTGACTATTCAAAAGAAACAATTGAA
AAGTACTTGTGGGATACTTTGAACGCAGGGAGAGTTGTTCCTGGTTATGGCCATGCGGTT
TTGAGAAAAACTGATCCTCGTTATACGGCTCAACGTGAATTCGCATTGAAACATTTCCCA
GATTACGAGTTATTTAAGTTGGTCTCCACCATTTATGAAGTTGCCCCAGGGGTTTTAACT
AAGCATGGTAAAACTAAGAACCCATGGCCAAATGTTGATTCACATTCCGGTGTTTTATTG
CAATACTATGGTCTAACTGAGGCTTCGTTCTACACTGTATTGTTTGGTGTTGCCAGAGCT
ATTGGTGTGTTACCCCAATTAATCATCGATAGGGCTGTTGGTGCTCCAATCGAAAGGCCA
AAATCATTCTCCACCGAAAAATACAAGGAGTTGGTAAAGAAAATCGAAAGTAAGAACTAA
Promoter Sequence
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>CIT1 YNR001C
TAATATTATAGCCTTTTTCAACAATGGAATCCCAACAATTATCTCAAAAATCACCTAAGC
CTCACATGCATGTTTTACGTTGTGGTTGATGATCTATTGATGTTGAGGTACCATATTTTG
AAATTCATTAAAACAACTTCTACCGGGCGTGTGGTCTAGAGGTATGATTCTCGCTTAGGG
TGCGGGAGGTCCCGGGTTCGAGTCCCGGCTCGCCCCCATTGATTTATTTTTATCAAATTT
TTTAATATTGCATATCTTTAGTGGGCAAAAAATTTTTCCCTGGGCAAAAATATAAGAGAG
CTCATCTTATTGTTGTCAGCCCAATGATTCCCTTGTCAAATTGAATTTTCGGATTTACTT
GTTCAGGTACCCGCGTTAAGGGGCTGCCGCGCCTGTCACTCTAAGAAAAAAGGAGCCATC
AAAAACCATTCAGCATTAACTAAAAACGCGGGTAGAGATTACTACATATTCCAACAAGAC
CTTCGCAGGAAAGTATACCTAAACTAATTAAAGAAATCTCCGAAGTTCGCATTTCATTGA
ACGGCTCAATTAATCTTTGTAAATATGAGCGTTTTTACGTTCACATTGCCTTTTTTTTTA
TGTATTTACCTTGCATTTTTGTGCTAAAAGGCGTCACGTTTTTTTCCGCCGCAGCCGCCC
GGAAATGAAAAGTATGACCCCCGCTAGACCAAAAATACTTTTGTGTTATTGGAGGATCGC
AATCCCTTTGGAGCTTTTCCGATACTATCGACTTATCCGACCTCTTGTTGTTTGAAAATG
TCAATTGATATCCATCCATTATATAAATGCTCAAAACTTGCAGCAACTATTCTTTACCCT
TCCCCTGTTATGGATTGCTAGTCTTAAGGGGGAAATTTGCTGTTTACTAAAATACAAACC
AGGTTTGTTTTGGCTTTTATTTGCATTTAAGTAATTACAATTACAACCATTAAAAAGAAA
ATAAGGCAAAACATATAGCAATATAATACTATTTACGAAG
Chr coordinates
Chr XIV from 631061-629622