Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name SEC12
Systematic Name YNR026C
Alias SED2
Strain S288c
Description Guanine nucleotide exchange factor (GEF); activates Sar1p by catalyzing the exchange of GDP for GTP; required for the initiation of COPII vesicle formation in ER to Golgi transport; glycosylated integral membrane protein of the ER; SEC12 has a paralog, SED4, that arose from the whole genome duplication
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>SEC12 YNR026C
ATGAAGTTCGTGACAGCTAGTTATAACGTCGGGTATCCTGCGTACGGTGCAAAATTTTTG
AATAACGACACATTACTTGTGGCAGGCGGTGGAGGAGAAGGAAACAATGGCATACCAAAC
AAGCTGACGGTCTTGCGCGTGGATCCTACCAAAGATACTGAGAAGGAACAGTTTCATATA
TTGAGCGAGTTTGCATTGGAAGACAACGACGACTCTCCTACTGCAATTGACGCTTCCAAG
GGTATCATTTTGGTTGGCTGCAATGAAAATAGCACTAAGATTACCCAAGGTAAAGGTAAT
AAGCACTTGAGAAAATTTAAATACGATAAAGTGAATGATCAATTGGAGTTCCTCACTAGT
GTAGACTTTGACGCATCTACAAATGCGGATGACTACACGAAGCTGGTTTATATTTCACGA
GAAGGTACCGTTGCAGCTATCGCATCATCTAAAGTACCTGCTATAATGAGAATCATTGAC
CCGAGCGACTTGACAGAGAAGTTTGAGATCGAGACTAGGGGTGAAGTAAAGGATTTACAC
TTTTCCACTGATGGTAAGGTTGTTGCTTATATCACCGGTTCTAGCTTGGAAGTGATTTCA
ACAGTGACTGGAAGTTGCATTGCTAGGAAAACAGATTTTGATAAGAATTGGAGTTTATCT
AAAATAAACTTCATAGCCGATGACACAGTATTGATAGCAGCCTCTTTAAAAAAAGGGAAA
GGTATTGTGCTGACCAAAATAAGCATCAAATCAGGAAACACTTCCGTATTAAGATCCAAA
CAAGTGACAAACAGATTCAAAGGGATTACTTCTATGGATGTCGACATGAAGGGTGAATTG
GCGGTACTGGCAAGTAATGACAATTCCATAGCTCTTGTGAAACTAAAAGACCTGTCAATG
TCTAAAATATTCAAACAAGCTCATAGTTTTGCCATTACAGAGGTCACTATCTCTCCGGAC
TCTACATATGTGGCGAGTGTTTCGGCAGCCAACACTATCCACATAATAAAATTACCGCTT
AACTACGCCAACTACACCTCAATGAAACAAAAAATCTCTAAATTTTTCACCAACTTCATC
CTTATTGTGCTGCTTTCTTACATTTTACAGTTCTCCTATAAGCACAATTTGCATTCCATG
CTTTTCAATTACGCGAAGGACAATTTTCTAACGAAAAGAGACACCATCTCTTCGCCCTAC
GTAGTTGATGAAGACTTACATCAAACAACTTTGTTTGGCAACCACGGTACAAAAACATCT
GTACCTAGCGTAGATTCCATAAAAGTGCATGGCGTGCATGAGACGAGTTCTGTGAATGGA
ACTGAAGTCTTATGTACTGAAAGTAACATTATTAATACTGGAGGGGCAGAGTTTGAGATC
ACCAACGCAACTTTTCGAGAAATAGATGATGCTTGA
Promoter Sequence
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>SEC12 YNR026C
GCGCTTAATGACAGCTGTGTGCAGCGGCGGTCGCCTAGTAACGAGTCAGTGAGCATGGCG
CTGATTAAATCACCACTTCCACTAAATTTTGCGTTGATCTTGGGGATTTCATAGAAGAAT
ATCTCTTCACTGGCCGAGCAATCAAACCCTGCTACTACGTAAGTGTCGTTGCTCAGGAAT
TCAGATAATTCCAGACTAGTGACAACTATTCGGCTTACTCGAGGGTACTTTTTATGAAAT
AGTTTAAATGCCTGCTTAGCGTCGTCTAAGGTACGAATTGACATCCCCACCAACAGTTCC
ATTTCAAACTGATTTGGTGTGGCCAAAAAAATTTTGAAGTTTTGTAAAATGTCTTGGTAT
ACCGCAACACATTCTCGATCCACGTACAGCCTTCCATTATCGCCCAGTACAGGATCTAAT
ATCCACTTGACGTTTTCACTCCCCTCACATAATTGACCCACTATTCCTGCTACCTTTTGC
AGGGCTTGAACATTGGGTAAATAGCCACTAAGTACGGCATCATACTTGATTCTAAGAGAC
CCAATCAAGCCCTTCTCTACAATGTCTACCAACTCCTCAGTGCTGCATTTGAAGCCTGTG
AAGTGGGCGTACCCCGAGTGGTTAGAAAACTGAACTGTGTTCAATACGTCCACATCCCAA
CCTCTGTATTGAAGTGGGAACGTAGCGGCCTTGTTTCCCACGTAGCCATGTATGACGTGT
GATTGAATGGAGAGCACTTTTTTTGTCGTATGTAATGTACTGGTCATTGGCACCACCCTC
ACACAGGCATGTATTCAACCTTCCACTGCGTCTGGTCTAATTTCTCAAAGCTAGTTATTA
TCTTTATCTTGAATGGTGATGACAATAGAGTAAGAATGAGGGAAAAAAGAAAAGTTGAAA
AAAAAAAAATCCAAAAAATTCAAAAACGTGTACAGAAACCTAGAAGGATACGTGATAGAA
ATACAGATATATAACAAGGTTGAGATACAATCGAGCCACT
Chr coordinates Chr XIV from 674689-673274
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