Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SEC12
Systematic Name
YNR026C
Alias
SED2
Strain
S288c
Description
Guanine nucleotide exchange factor (GEF); activates Sar1p by catalyzing the exchange of GDP for GTP; required for the initiation of COPII vesicle formation in ER to Golgi transport; glycosylated integral membrane protein of the ER; SEC12 has a paralog, SED4, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>SEC12 YNR026C
ATGAAGTTCGTGACAGCTAGTTATAACGTCGGGTATCCTGCGTACGGTGCAAAATTTTTG
AATAACGACACATTACTTGTGGCAGGCGGTGGAGGAGAAGGAAACAATGGCATACCAAAC
AAGCTGACGGTCTTGCGCGTGGATCCTACCAAAGATACTGAGAAGGAACAGTTTCATATA
TTGAGCGAGTTTGCATTGGAAGACAACGACGACTCTCCTACTGCAATTGACGCTTCCAAG
GGTATCATTTTGGTTGGCTGCAATGAAAATAGCACTAAGATTACCCAAGGTAAAGGTAAT
AAGCACTTGAGAAAATTTAAATACGATAAAGTGAATGATCAATTGGAGTTCCTCACTAGT
GTAGACTTTGACGCATCTACAAATGCGGATGACTACACGAAGCTGGTTTATATTTCACGA
GAAGGTACCGTTGCAGCTATCGCATCATCTAAAGTACCTGCTATAATGAGAATCATTGAC
CCGAGCGACTTGACAGAGAAGTTTGAGATCGAGACTAGGGGTGAAGTAAAGGATTTACAC
TTTTCCACTGATGGTAAGGTTGTTGCTTATATCACCGGTTCTAGCTTGGAAGTGATTTCA
ACAGTGACTGGAAGTTGCATTGCTAGGAAAACAGATTTTGATAAGAATTGGAGTTTATCT
AAAATAAACTTCATAGCCGATGACACAGTATTGATAGCAGCCTCTTTAAAAAAAGGGAAA
GGTATTGTGCTGACCAAAATAAGCATCAAATCAGGAAACACTTCCGTATTAAGATCCAAA
CAAGTGACAAACAGATTCAAAGGGATTACTTCTATGGATGTCGACATGAAGGGTGAATTG
GCGGTACTGGCAAGTAATGACAATTCCATAGCTCTTGTGAAACTAAAAGACCTGTCAATG
TCTAAAATATTCAAACAAGCTCATAGTTTTGCCATTACAGAGGTCACTATCTCTCCGGAC
TCTACATATGTGGCGAGTGTTTCGGCAGCCAACACTATCCACATAATAAAATTACCGCTT
AACTACGCCAACTACACCTCAATGAAACAAAAAATCTCTAAATTTTTCACCAACTTCATC
CTTATTGTGCTGCTTTCTTACATTTTACAGTTCTCCTATAAGCACAATTTGCATTCCATG
CTTTTCAATTACGCGAAGGACAATTTTCTAACGAAAAGAGACACCATCTCTTCGCCCTAC
GTAGTTGATGAAGACTTACATCAAACAACTTTGTTTGGCAACCACGGTACAAAAACATCT
GTACCTAGCGTAGATTCCATAAAAGTGCATGGCGTGCATGAGACGAGTTCTGTGAATGGA
ACTGAAGTCTTATGTACTGAAAGTAACATTATTAATACTGGAGGGGCAGAGTTTGAGATC
ACCAACGCAACTTTTCGAGAAATAGATGATGCTTGA
Promoter Sequence
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>SEC12 YNR026C
GCGCTTAATGACAGCTGTGTGCAGCGGCGGTCGCCTAGTAACGAGTCAGTGAGCATGGCG
CTGATTAAATCACCACTTCCACTAAATTTTGCGTTGATCTTGGGGATTTCATAGAAGAAT
ATCTCTTCACTGGCCGAGCAATCAAACCCTGCTACTACGTAAGTGTCGTTGCTCAGGAAT
TCAGATAATTCCAGACTAGTGACAACTATTCGGCTTACTCGAGGGTACTTTTTATGAAAT
AGTTTAAATGCCTGCTTAGCGTCGTCTAAGGTACGAATTGACATCCCCACCAACAGTTCC
ATTTCAAACTGATTTGGTGTGGCCAAAAAAATTTTGAAGTTTTGTAAAATGTCTTGGTAT
ACCGCAACACATTCTCGATCCACGTACAGCCTTCCATTATCGCCCAGTACAGGATCTAAT
ATCCACTTGACGTTTTCACTCCCCTCACATAATTGACCCACTATTCCTGCTACCTTTTGC
AGGGCTTGAACATTGGGTAAATAGCCACTAAGTACGGCATCATACTTGATTCTAAGAGAC
CCAATCAAGCCCTTCTCTACAATGTCTACCAACTCCTCAGTGCTGCATTTGAAGCCTGTG
AAGTGGGCGTACCCCGAGTGGTTAGAAAACTGAACTGTGTTCAATACGTCCACATCCCAA
CCTCTGTATTGAAGTGGGAACGTAGCGGCCTTGTTTCCCACGTAGCCATGTATGACGTGT
GATTGAATGGAGAGCACTTTTTTTGTCGTATGTAATGTACTGGTCATTGGCACCACCCTC
ACACAGGCATGTATTCAACCTTCCACTGCGTCTGGTCTAATTTCTCAAAGCTAGTTATTA
TCTTTATCTTGAATGGTGATGACAATAGAGTAAGAATGAGGGAAAAAAGAAAAGTTGAAA
AAAAAAAAATCCAAAAAATTCAAAAACGTGTACAGAAACCTAGAAGGATACGTGATAGAA
ATACAGATATATAACAAGGTTGAGATACAATCGAGCCACT
Chr coordinates
Chr XIV from 674689-673274