Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
COS10
Systematic Name
YNR075W
Strain
S288c
Description
Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>COS10 YNR075W
ATGGGGGAAGAGATTAGACTTTTGTCCTCTAAAGGTCTTGAGACCCATAGTAGCTTTTGT
TTGCCCGAGGATATTTTCAGAAACCGTTTAACATGGTTGTGCAGTGAGATTCGCAACTCA
GGATTTTGGATCTGGTCGCTATCATGGTTACCGCTTGCCGTTTGGTGGGGGATGGCCAGT
ACTTGGTTTTATCCCCTTCTGACTTCAGTAGTTCTAATCCTGGCGCTAATTGCTATTTTG
CCAGTAGTTCAAATACAGTACAGTAAATATACTTTATCAAATCAACTCACCCAGCTTTCT
AAAGAAATCATCAAAAGTGCACCAGGTGCATACTCTGCTGATTGGGACGCTGTTGCAATA
CATTTCAATTCCTACTTGTATGAAAACAAAGCATGGAAAACTGCACATTTTTTTTTTAAT
GGTACTGACTGCCAAGAAGCATTCAGGAAAACCATTCTAGAGCCAGCTGTTTTGAGGAGA
CAAAACGAAGATCCTAGGTTCAGTTCAATTGAGATTTTGGTCCCTTACACCGAAGACGCG
GTGCAGGTTTATTTTACAAAAGTAAACGCACAGTGGAGGTTGATCCATGGTAAGAAGGAA
TGCAAACTTACTATGTTGGAAAATGTCAAGCTTCCTAAGGAAACCTATCGCTGCAAGCTA
GCATGGAGTTGCCAGAGAATCAGGATTTCTTTCTCTCCACTAGACTTCCTTCCTGATATG
TCTGACTTCTTTATTTGTGCAAATTTATCACCAGCATGCTTGGTATCTTATTGGCTAATA
GACATTTTCTTTAGAATGATAGATGATTTTCAAAACATAAGGCCTAAATCGATGAAAGTT
GATGATAAAATGCAGTACCTATCAGATATTATAAACGAGCAGGGTGCTAGCCCTGAAAAA
TGGGATACAATTGCAAGGAAAACGAATACACGATTATTTGAAAAGAGGGTCTGGAAAAAC
GAAGAGTTTTTCTTTGATGGGACTGATTGTCAGGCATTCTTTGAACGGAACTTTAGTAGC
CTTTTGTTCTCAAAAAAATCTGCGTCGCCTAGATCATTAAACGTTGAACTTTGGAAATAC
ATTCAAGAAGCGCAATTGAGCTGTAACTATGAGCCGTTACCATAA
Promoter Sequence
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>COS10 YNR075W
CATGCAGGGTGGACATTCAATTAATTTTTATCGCTTTTTAACGATTACTAATCCAGTATT
ACCAACTACAATCACTCAGTCATGTATCACTAATAACGAAAAGTAAGCTGTACAATGCTC
ATCTTCCTAGCACTACTAGTACTGCTACTATGAGACACCATTGAAGTCTTCTTCAAGACC
CCCATTATGAGAACACTTGGCTCACTATACAATCGGCGGGAGATGGGTTGTTATTATAGA
GAGTTTCAGGAAAAGCACTCCTAGATTCTAGTCAAGTACTGCCTATTGTATAAGAGACGA
GGGCACGAGATAGCGCAGTATTTTATGATGAAAATATGAAAATAAATACTTAACTCATTG
AGTAAGCTTAGCTGGGCAACTTAACTAACAGTCAAAAAAAAAAAAAAAAAAAAAAAACAA
GAGCCAGCAAACTGACATTAACATTGATCAATAAAATAAGAAAAAATGTACCAGAGAATT
CGATTATGAACTGATGACAATATCATTAAAGACTTTGCACAGTATTCAAAAACTAATCGA
GAGCTTTGACCAAAAAGTGTCCCGACTTTATAATGAGACCGCCGCTTAATTCATAGGAGT
TATATGGTATGCTTTGGAAAGCTATTACATTGTTTGATAATTCAAAAATAAGCCACAATA
CTTCACCTATTGTGTACCATGTATTATAAAACATCGCAGCTCGTATCTGTAAACATACAT
TGACTTACATTTTAGTGATAACTTGGGTACTTGAGTGAAGTCCATTTCTCCCGTGCTTCC
GGAACATAAACCAACATAGATTCTCTTTCACTCGAAACTGCTCGAAGCTGTTGCTCTTTT
TTTGATCGTGGCTTTAACTATAAAACTCAACAGCTGCGTGATGAACGCGCTGTCAACAAA
TTTCATCTTGCGAATTATATAAAAAACACTGCGAGTGATTAAACCTCAGTAAACTTGTTA
CGTACCTCATAACATTAATGTGAAATACACTATATTGAAT
Chr coordinates
Chr XIV from 779916-781040