Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
IRA2 Systematic Name
YOL081W Alias
CCS1, GLC4 Strain
S288c Description
GTPase-activating protein; negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions; IRA2 has a paralog, IRA1, that arose from the whole genome duplication; defects in human homolog NF1 are associated with neurofibromatosis External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA View Seq
Sequence hidden Promoter Sequence
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>IRA2 YOL081W
CGAAACTCTTTACTTCCTAAGGCCTCTCATTACTTATCACCTAGCATCATGCTCTTCATA
CATGCCATCTACTTTCAAACGATATACGGCTAACCAGAAAAGTACGGACAATCAGGGACG
AGCAGGGACATGACGCCTTCCGCACAGATCCCAGAGAAAAGCAGGGAAACAAGAAAATAA
GAAAACAAGAAAAACAGTAGTTACCCTTGTAAGTGTCATCCACAACAGAACCAATACTCT
TACTCTTCCGCTCATTCCCCGCAGAATGATAGAACTATTCTAAATCCCCTTGCCTTGCTT
GGCCTTGACTTGGGTTGGGACTTGGACCTCTAGAACCGATGTGCCTTCAAACATCTTAGC
GAGATAAGAGTCTGCCATTAATGCATCGAGCCAATATCTTGGACTAGTACGAGGTTCACG
TAGCCTTTCTTGCACGGCACCAGCGTCCCACCCCAAGTTCTTTGCTATACTGACCGCCTT
ACACATTTTAGTGTGATTCCAACCCAAAGTAGCTCCTCAAAAAGGGTCACCCGATCGGTG
AATCAATCCGCGGCGCAGAAATGTTCGTAGAGCTCTCGTTTCTTCTAGAACGCTCCCTTG
ATGAAACGAAAATTTCCATCACAATAAAGCTCGCACGCCTTTTTGAAAACCCCAAGCTTT
GCTGTGTCTTCTTGTGAAAAGTTTTGCCCAACGATTATCTATTCTACATATAACCGGGGA
GTTAAGCACATCCTATTGCCCTACATTCTCTCCGCTTACTTCATTGTCTAGAGCTCCTGG
GAAACAAAAGACCGAAAAAGCGAAAACAAAATCAGAACAAGGCTTAAGTACTTTTTCACC
AATTGTAGCAAACATTTAACCACATTTTAGCACACTAGCATATAGCATTGTCCTCTGTTA
TTCGTTTTGCTTTTCTCCTTTAGTGTTACTTTTCCCCCAACGTTACACCATTTTTTGATA
TCAACTAAACTGTATACATTATCTTTCTTCAGGGAGAAGC
Chr coordinates
Chr XV from 171070-180309
