Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name IRA2
Systematic Name YOL081W
Alias CCS1, GLC4
Strain S288c
Description GTPase-activating protein; negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions; IRA2 has a paralog, IRA1, that arose from the whole genome duplication; defects in human homolog NF1 are associated with neurofibromatosis
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>IRA2 YOL081W
CGAAACTCTTTACTTCCTAAGGCCTCTCATTACTTATCACCTAGCATCATGCTCTTCATA
CATGCCATCTACTTTCAAACGATATACGGCTAACCAGAAAAGTACGGACAATCAGGGACG
AGCAGGGACATGACGCCTTCCGCACAGATCCCAGAGAAAAGCAGGGAAACAAGAAAATAA
GAAAACAAGAAAAACAGTAGTTACCCTTGTAAGTGTCATCCACAACAGAACCAATACTCT
TACTCTTCCGCTCATTCCCCGCAGAATGATAGAACTATTCTAAATCCCCTTGCCTTGCTT
GGCCTTGACTTGGGTTGGGACTTGGACCTCTAGAACCGATGTGCCTTCAAACATCTTAGC
GAGATAAGAGTCTGCCATTAATGCATCGAGCCAATATCTTGGACTAGTACGAGGTTCACG
TAGCCTTTCTTGCACGGCACCAGCGTCCCACCCCAAGTTCTTTGCTATACTGACCGCCTT
ACACATTTTAGTGTGATTCCAACCCAAAGTAGCTCCTCAAAAAGGGTCACCCGATCGGTG
AATCAATCCGCGGCGCAGAAATGTTCGTAGAGCTCTCGTTTCTTCTAGAACGCTCCCTTG
ATGAAACGAAAATTTCCATCACAATAAAGCTCGCACGCCTTTTTGAAAACCCCAAGCTTT
GCTGTGTCTTCTTGTGAAAAGTTTTGCCCAACGATTATCTATTCTACATATAACCGGGGA
GTTAAGCACATCCTATTGCCCTACATTCTCTCCGCTTACTTCATTGTCTAGAGCTCCTGG
GAAACAAAAGACCGAAAAAGCGAAAACAAAATCAGAACAAGGCTTAAGTACTTTTTCACC
AATTGTAGCAAACATTTAACCACATTTTAGCACACTAGCATATAGCATTGTCCTCTGTTA
TTCGTTTTGCTTTTCTCCTTTAGTGTTACTTTTCCCCCAACGTTACACCATTTTTTGATA
TCAACTAAACTGTATACATTATCTTTCTTCAGGGAGAAGC
Chr coordinates Chr XV from 171070-180309
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