Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
MDH2
Systematic Name
YOL126C
Strain
S288c
Description
Cytoplasmic malate dehydrogenase; one of three isozymes that catalyze interconversion of malate and oxaloacetate; involved in the glyoxylate cycle and gluconeogenesis during growth on two-carbon compounds; interacts with Pck1p and Fbp1; mutation in human homolog MDH2 causes early-onset severe encephalopathy
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>MDH2 YOL126C
ATGCCTCACTCAGTTACACCATCCATAGAACAAGATTCGTTAAAAATTGCCATTTTAGGT
GCTGCCGGTGGTATCGGGCAGTCGTTATCGCTGCTTTTGAAAGCTCAGTTGCAATACCAG
TTAAAGGAGAGCAACCGGAGCGTTACCCACATTCATCTGGCTCTTTACGATGTCAACCAA
GAAGCCATCAACGGTGTTACCGCCGACTTGTCTCATATAGACACCCCCATTTCCGTGTCG
AGCCACTCTCCTGCAGGTGGCATTGAGAACTGTTTGCATAACGCTTCTATTGTTGTCATT
CCTGCAGGTGTTCCAAGAAAACCTGGCATGACTCGTGATGACTTATTTAACGTGAATGCT
GGTATCATTAGCCAGCTCGGTGATTCTATTGCAGAATGTTGTGATCTTTCCAAGGTCTTC
GTTCTTGTCATTTCCAACCCTGTTAATTCTTTAGTCCCAGTGATGGTTTCTAACATTCTT
AAGAACCATCCTCAGTCTAGAAATTCCGGCATTGAAAGAAGGATCATGGGTGTCACCAAG
CTCGACATTGTCAGAGCGTCCACTTTTCTACGTGAGATAAACATTGAGTCAGGGCTAACT
CCTCGTGTTAACTCCATGCCTGACGTCCCTGTAATTGGCGGGCATTCTGGCGAGACTATT
ATTCCGTTGTTTTCACAGTCAAACTTCCTATCGAGATTAAATGAGGATCAATTGAAATAT
TTAATACATAGAGTCCAATACGGTGGTGATGAAGTGGTCAAGGCCAAGAACGGTAAAGGT
AGTGCTACCTTATCGATGGCCCATGCCGGTTATAAGTGTGTTGTCCAATTTGTTTCTTTG
TTATTGGGTAACATTGAGCAGATCCATGGAACCTACTATGTGCCATTAAAAGATGCGAAC
AACTTCCCCATTGCTCCTGGGGCAGATCAATTATTGCCTCTGGTGGACGGTGCAGACTAC
TTTGCCATACCATTAACTATTACTACAAAGGGTGTTTCCTATGTGGATTATGACATCGTT
AATAGGATGAACGACATGGAACGCAACCAAATGTTGCCAATTTGCGTCTCCCAGTTAAAG
AAAAATATCGATAAGGGCTTGGAATTCGTTGCATCGAGATCTGCATCATCTTAA
Promoter Sequence
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>MDH2 YOL126C
TTTCTTTTTTTCCATGAAATATTCACATTGCAACCTTTCTGAGGGTTTCGCCCTCTTAAC
AGCGGGCCCATTATTATCTTGTAACATCCTTCGCTAAATAATAAACCTGAACTGTACTTA
GCGAAGCCTTCATAGCACCTACGTACACGTATATATAGACATTTTACGTAATGGAGAAAC
TGAGGTTTTTGTTTTCACTTTTTTTCTTTCTTTTTCACTATTGCTCGAACCGCCTGCGAT
GAGCTAAGAAAAAAAAGTGAAAGAAATCATAGAAAGCAAAAATGAGATTATATAGCCCAG
AGCCCTCTTCTGGCGCCTGTCCCAAGGCGGACCAACAACAACACTTGCCCAAACCTAAGA
AAATCCCCTCATACTTTTCCGTTTGTATCTCCTACTTTCTTACTTCCTTTTTTTCTTCTT
TATTTGCTTGGTTTACCATTGAAGTCCATTTTTACTACAGACAATAGCTAGTCATTCGCT
ATCTTCCGTTTGTCACTTTTTTTCAAATTTCTCATCTATATAGCGAAGTACGGAAAAGAT
GTCACTTGCCGGCATCTCGGCCTTCCCCGGCCAAATGGACTCATCATCTACGATACGGCC
CCTTTAATCCGCAATTACTTTGCCCATTCGGCCGTAGCCGTTCTAAAGCCGCCGTGCCTT
GCCCCCAATACTCCCCTAATGATCCGGGAAGTTCCGGTTTTTTTCCTTTGTTTAGTGGCA
TTTTGTGTTGCCCAAGGTTGGGAAGGTCCGATTTGACTTTAAGGAACTACGGAAGGTATC
TAAGGTTTCTAAAAACAATATACACGCGCGTGCGTAGATATATAAAGATAAAGATTTATC
GATATGAGATAAAGATTGCTGCATGATTCTCCTTCTGATTCTTTTTCCCTGTATATATTT
TCTCCCCTTCTGTATAAATCGTACAGTCAGAAGTAGTCCAGAATATAGTGCTGCAGACTA
TTACAAAAGTTCAATACAATATCATAAAAGTTATAGTAAC
Chr coordinates
Chr XV from 82920-81787