Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
DNL4
Systematic Name
YOR005C
Alias
LIG4
Strain
S288c
Description
DNA ligase required for nonhomologous end-joining (NHEJ); forms stable heterodimer with required cofactor Lif1p, interacts with Nej1p; involved in meiosis, not essential for vegetative growth; mutations in human ortholog lead to ligase IV syndrome and Dubowitz syndrome
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>DNL4 YOR005C
ATGATATCAGCACTAGATTCTATACCCGAGCCCCAAAACTTTGCGCCTAGTCCAGATTTC
AAATGGCTTTGTGAAGAGCTATTTGTGAAGATACATGAAGTTCAAATTAATGGAACGGCC
GGCACTGGCAAATCAAGGTCTTTCAAGTACTATGAAATAATATCGAATTTCGTCGAAATG
TGGAGAAAAACCGTGGGAAATAATATATATCCTGCACTGGTTCTTGCTCTTCCCTACCGC
GATAGACGAATCTATAATATTAAGGATTATGTATTAATAAGAACTATATGCTCTTACTTG
AAGTTGCCAAAAAATTCTGCAACAGAGCAGCGGTTAAAAGATTGGAAACAGCGTGTCGGT
AAAGGTGGGAATCTTTCTTCTCTTCTTGTGGAAGAAATTGCTAAAAGAAGGGCTGAACCT
AGCTCAAAAGCGATTACAATTGATAACGTCAATCACTATCTGGATAGTTTGAGTGGAGAC
AGGTTCGCTTCCGGACGAGGATTTAAGAGTCTTGTCAAGTCCAAACCTTTCCTGCACTGT
GTGGAGAATATGAGTTTCGTCGAATTAAAATACTTCTTTGATATCGTGCTTAAAAATAGA
GTAATAGGAGGTCAAGAGCACAAATTGCTAAACTGCTGGCATCCTGATGCTCAGGATTAT
CTTAGCGTGATATCTGATTTAAAGGTGGTAACTTCAAAACTTTATGATCCAAAAGTTCGT
CTAAAGGATGATGATTTGAGTATAAAAGTTGGCTTTGCATTCGCCCCCCAATTAGCCAAA
AAAGTGAATCTTTCTTATGAGAAAATATGCCGTACACTACATGATGATTTTTTGGTAGAA
GAAAAAATGGATGGAGAACGAATTCAAGTTCATTATATGAATTATGGTGAATCCATAAAA
TTTTTTAGTAGACGGGGCATCGACTATACCTATTTGTACGGAGCGAGCTTATCATCAGGA
ACTATATCTCAACATTTGAGGTTTACAGATAGTGTTAAAGAATGTGTTTTAGATGGAGAA
ATGGTGACGTTTGATGCAAAAAGACGGGTGATTCTTCCATTCGGTCTTGTTAAAGGAAGT
GCAAAGGAAGCGCTATCTTTTAATAGTATAAATAATGTTGACTTTCACCCCTTATATATG
GTGTTTGATCTGTTATACCTGAATGGGACTTCGTTGACACCATTACCCCTTCATCAAAGG
AAGCAATATCTGAACAGCATTTTAAGTCCCTTGAAAAATATTGTAGAAATAGTACGATCT
TCTAGATGTTATGGTGTGGAGTCAATCAAAAAGTCTTTAGAAGTTGCAATCTCACTGGGT
TCAGAAGGAGTTGTTTTGAAATATTATAATTCAAGTTATAATGTCGCCAGTCGAAACAAC
AACTGGATCAAGGTAAAACCTGAATATTTGGAGGAATTTGGAGAGAATTTAGACTTAATA
GTAATAGGCAGAGATTCTGGGAAAAAAGATTCTTTTATGCTAGGGTTACTTGTGCTAGAT
GAAGAAGAGTATAAAAAGCACCAAGGAGACTCCTCTGAAATTGTAGACCACTCAAGCCAA
GAAAAACACATACAAAATTCAAGAAGAAGGGTGAAAAAAATACTTTCATTCTGTTCTATC
GCAAACGGTATATCTCAAGAAGAATTCAAAGAAATCGACCGCAAAACGAGAGGACATTGG
AAAAGAACCTCCGAAGTTGCTCCCCCTGCTTCAATTTTAGAATTTGGCTCAAAAATACCT
GCCGAATGGATTGACCCCAGTGAATCAATTGTTCTAGAAATAAAATCACGGTCTTTGGAT
AACACAGAAACGAATATGCAGAAGTACGCTACCAATTGTACTTTGTACGGTGGCTATTGT
AAAAGAATACGGTACGATAAAGAATGGACAGATTGTTACACACTTAACGACTTATACGAA
AGTAGGACGGTTAAATCTAACCCCAGCTATCAAGCGGAAAGGTCACAGCTTGGATTGATA
CGGAAAAAGAGAAAGAGAGTACTTATTTCAGACAGCTTTCACCAAAACAGGAAACAACTG
CCAATTTCAAACATCTTTGCCGGATTACTTTTTTATGTTCTCTCTGACTATGTCACGGAG
GACACTGGAATACGGATTACACGGGCAGAACTTGAAAAAACTATTGTGGAACATGGTGGT
AAACTGATATATAATGTAATTTTAAAACGTCATTCAATTGGGGACGTTCGGTTAATCAGC
TGTAAAACTACCACGGAATGCAAGGCTTTAATAGATCGAGGATATGATATATTGCACCCA
AATTGGGTACTCGATTGTATAGCATATAAGAGGCTCATCCTGATCGAGCCCAATTATTGC
TTTAACGTCTCTCAAAAAATGAGAGCCGTCGCTGAAAAAAGGGTAGATTGTTTGGGTGAT
AGTTTTGAAAATGACATTTCGGAAACCAAACTGTCATCATTGTATAAATCACAACTAAGT
CTACCACCGATGGGGGAACTCGAGATAGATTCTGAGGTTCGGCGGTTTCCATTATTTTTA
TTCTCCAACAGGATTGCATACGTACCACGTCGCAAAATTAGCACAGAAGATGACATTATA
GAAATGAAAATTAAGTTGTTTGGTGGAAAAATAACAGATCAACAGTCACTTTGTAACTTA
ATAATTATACCATATACTGATCCTATTTTGAGGAAAGACTGCATGAATGAGGTACACGAA
AAAATAAAAGAACAAATAAAGGCTTCTGATACTATACCGAAAATAGCCAGGGTCGTTGCC
CCTGAATGGGTGGATCATTCTATTAATGAAAACTGTCAAGTGCCTGAAGAAGACTTCCCC
GTAGTCAACTACTGA
Promoter Sequence
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>DNL4 YOR005C
TGTTTGCCCTGATGATCTAGAAATTGTCGAACAACACGGCGCTTCGGTGGTCGAGTGTTC
TTGGGCACGTTTAGAAGAGGTACCCTTCAATAAAATAGGCGGTAAGCACGAAAGGCTGCT
GCCGTATTTAGTGGCCGCTAATCAAGTAAATTACGGGAGACCATGGAGGCTCAATTGCGT
TGAGGCATTAGCGGCTTGTTTTGCTATCGTCGGGAGAATGGATTGGGCCAGTGAATTGTT
ATCACACTTCTCGTGGGGAATGGGATTTTTAGAATTAAACAAAGAATTGCTTGAAATCTA
TCAGCAGTGCACTGACTGCGACTCTGTAAAGAGGGCTGAAGAGGAATGGTTGCAAAAATT
AGAAAAGGAAACTCAAGAACGAAAATCCCGAGCTAAAGAAGAAGATATATGGATGATGGG
TAACATAAATAGAAGGGGTAATGGTTCGCAATCTGACACATCAGAGAGTGAGGAAAACTC
AGAACAATCTGATTTGGAAGGCAATAATCAATGTATTGAATATGACTCTTTAGGTAATGC
TATTCGTATAGATAACATGAAAAGCAGGGAAGCGCAATCTGAGGAATCAGAAGACGAGGA
AAGTGGTTCAAAAGAAAATGGAGAGCCTTTAAGTTATGACCCCTTAGGCAATTTAATTCG
ATAGGTGATTAAATAGGCTGAAATCAGTGTTTAGTAACTACGTACGTTGTACATGTAACA
TTGTGATATAAATCGTAAGATTCGCCGAGTATAGATCAATAATATCGGTTTCATCACTTA
CGTTGTTTGTGCAGTACTAGAGTTAAGATCGTTTTCGATCCCTTATTTTCTTCTTTTTTC
CTTTTTTTTGTTATTTTTCTCTTTTTACCTTTTGTCACCATATTAAATCTTTAAACAAAT
CTAACTATGAAAAAATCCTTTAAACATATGTTAATATGTGGAAAATAAATACTAAAATAA
AAATCTAGAACTGAAGGAAATAGTAACGGATTATTTAGGT
Chr coordinates
Chr XV from 337343-334509