S.cerevisiae - Yeastract

Locus Information

Standard Name	CUE5
Systematic Name	YOR042W
Strain	S288c
Description	Ubiquitin-binding protein; functions as ubiquitin-Atg8p adaptor in ubiquitin-dependent autophagy; serves as proteaphagy receptor for inactivated 26S proteasomes; contains CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination; CUE5 has a paralog, DON1, that arose from the whole genome duplication; human TOLLIP is a functional CUE-domain homolog, can complement yeast null mutant, rescuing hypersensitivity of cue5 null mutant cells to Htt-96Q
External sources	Open in SGD Open in KEGG

Gene Sequence Download FASTA View Seq	Sequence hidden
Promoter Sequence Download FASTA	>CUE5 YOR042W TAAGAGTAACATGTATTAGGACTCCATGCCATACAAAAGATTCCATATGCTATTATATCA AAGATTTAGAAACAGGTGAGCAGTGCATCTTCACAGGCGACACTTTATTCATTGCCGGTT GTGGGAGGTTTTTCGAGGGCACAGGAAGAGATATGGACATGGCCTTAAACCAGATAATGT TAAGGGCTGTTGGTGAGACGAACTGGAATAAGGTTAAAATATACCCTGGTCATGAGTACA CCAAAGGCAATGTTAGCTTTATCAGAGCAAAAATCTATTCCGATATAGGGCAGAACAAGG AGTTTGATGCGTTGGAACAGTATTGCAAATCTAACGAGTGCACCACCGGTCACTTCACCC TGAGAGATGAACTAGGTTATAACCCATTCATGAGATTGGATGATCGTGCCGTTAGACTAG CAGTCGGCGATACTGCTGGGACTTATCCCAGATCCGTAGTGATGCAAGAGTTAAGAAAGC TTAAAAACGCTATGTAACTGGCATGCAGTCTAAATATTTGCAAAGTATGTCTGAAGGACT AATGATAGGTGGGTCAGGATATCAGCTTAATCCTCACCCATGAAGAAGAAGATATGTCAA AAGCCATATTCAGTAATTGGTCTATTTGTCTCCGTTGTCCACGCTTTCATAGCCATAGAG GAAAAGGCGTAGAAAGTTCTATATAACAGAGTATTTAGTATTATATTCCCGAGGTTTTAG GAAAGAAAGAAGAAGAAAGAGAAGGAGGAAAATGGGAAGAAACTTAAGATTGAAAGTGTG AGAAAAATGAATGGCCCTCTCTTTATATAGTGTTCAAAAAATTGAACAGCGATTTATTGT CATCACAGACGTTGAGTCTCTCTCTTTTCCTATTAAAATTAATCTTAGCAAGTAAGGGCT TGGAGGGAAGATAGCGTTGAGCTGTGAAGTCGATCAAATAAACAGCTTGAGACTAGTTAA GTAGCCACCCCCAGCAAAACGATATTGCCAAATCAAAATC
Chr coordinates	Chr XV from 408425-409660