Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name TMC1
Systematic Name YOR052C
Alias YOR29-03
Strain S288c
Description AN1-type zinc finger protein, effector of proteotoxic stress response; stress-inducible transcriptional target of Rpn4p; induced by nitrogen limitation, weak acid, misfolded proteins; short-lived protein, degraded by proteasome; may protect cells from trivalent metalloid induced proteotoxicity; contains PACE promoter element; ortholog of human AIRAP, which stimulates proteasome activity in response to arsenic; protein abundance increases under DNA replication stress
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>TMC1 YOR052C
ATGTCTGATATAAACGAAATCGAAATTCCATCCAGAAAGGATGAAATTAGACAAGTTACT
CCCAAGGATCCCATGCATGAGATCGAGGATAAAAGCACATACCACGCTAAGATAAAGAAA
TCAGATTCCGGGACCGTCCTGGGTGCTATACCGTTGAATTCAAGGTCTTCTAGTAACTCT
AGCGTGACATCGACGGGTCAGAGCAGTAGGCGGGTGACTAAGAAAACGACCAAGAAGAAA
AAGAAGAATGCTTGTTATTTCGATACCTGTTCAAGTGCGGCTTCGAAATTCATCGGTGAC
TGTAATTTTTGCAAAGGTCACTTTTGCTCGAAACACAGATTAATGGAAAACCATGCTTGT
AATGGCTTAACGAGCTGCAAAGAACAGCTACATCAAAGAAACGCTGATAAGCTAGAAGCT
GAACAAACTAAGGCTCCAAAGATACAAATTTAA
Promoter Sequence
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>TMC1 YOR052C
GCATAAACGGTGACATCGGGTTAAGTGGGATGATGGATGCAAATGAGATTGTTGGCAAGA
TAGTCGTCAAACTAGGTGGTTATCCCGATGTTTCTGCGGGAAAGGAAGAAGAAGAGGATG
AAGATAACGATGAGGAGGATGATAATAAGAAGAACGATACTGGTGGTAAAGATGAAGATA
ATGACGACGACGACGATGACGATGATGATGATGACGATGATGACGACGACGACGACGACG
ACGACGACGACGACGACGACGATGATGATGATGACGACGATGATGACGACGATGATGACG
ACGACGACGACGACGATGAAGATGACGAAGACGAAGATGAAGACGATGAAGGAAAAAAGA
AAGAAGATAAAGGAGGGCTACAGCGATCTTAAATAGGACTAATTTCATTATTGTAAAACT
TTTGAACTATATATATCTTTACATAGAATAAATTTGCATTAATCACTGATAACCAGAAGA
GAAGGCTAAAAATAGGCAAGTAGGACACTTAACTCATTTTCCAAAGGGAGTTTTATGTCT
CATAGTTAGCGCTTACGATGCTGCGGAGGTGCGTCGTCACTCTATCGGATGTTCATTCTG
AGGGAAAGGGAGTGGTTCAAATCCGATTTAACCTTGCCAGCTTATCGCAAAGCGGGTGAG
ATCAAATGCTCCACAGCTCTGCGGTTCGTTTCACCTTTCTGTTTTCTGCGAGCTTCGGCC
CTGTCAGGGAAAAAAAGAAAGAAGGGGGCGGTGGCAAAGACTGCATCGGCCCAGAAGCAA
AGAAGATATAAAAGGGAAATACTTGCCACCGAAGTCTTAGACTTTGCATAAGAGATATTC
TCGCCTTTCCCGCTTGAAGAGTTCCTGACTCTATCATACATCTTGGATAAAAGGATCAAG
CAGCCTATCCGCTAAACCGCTATTTATTCTGCTTTACTGATTCATTTACATCAAGTGAAG
CACAAAACTATCAAAATCACCAAAAGAATAGAAACTAAAA
Chr coordinates Chr XV from 427224-426772
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