S.cerevisiae - Yeastract

Locus Information

Standard Name	TCB1
Systematic Name	YOR086C
Alias	tricalbin
Strain	S288c
Description	Lipid-binding ER protein involved in ER-plasma membrane tethering; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to plasma membrane and regulate PI4P levels by controlling access of Sac1p phosphatase to its substrate PI4P in PM; contains 3 calcium and lipid binding domains; non-tagged protein also localizes to mitochondria; C-termini of Tcb1p, Tcb2p and Tcb3p interact; TCB1 has a paralog, TCB2, that arose from the whole genome duplication
External sources	Open in SGD Open in KEGG

Gene Sequence Download FASTA View Seq	Sequence hidden
Promoter Sequence Download FASTA	>TCB1 YOR086C GAGATCCATTGTTTTCCGGCATGCACTGTTCGTTAGAAATTGGCAAGTGCAAGTCGCCGT TGGCTGATACCATAATGCTCCTGTTCTAGTAATATTATATTTTATAACTGAATTCTATTG CCTTACCAAGCCACTGATTAATGACAATTGCATTGAATAGGCTCTAGCTGATCCTCGAAG GATACTGACTAAATTTACCACATATTTTCAGCTCTTATGAGATAACTCCGACATAGCAAC AGTGTAGGAGAAAAATTAAAAAATTAACGACCCCAGTGAGGGTTGAACTCACGATCTTGC GATTAACAGTCGCACGCCTTAACCAACTTGGCCATGGAGTCTAACTTTGTTGTTTTAGAG AACGAATGAAGAACTTATTATGACGATAAAAATATGTCAAGAGAGGCCCAAGAATGTATA AATCATTGTAAAACCAAGCAAGTAACAAAAATGGTCATGTGACAAGAGGTGGTGACATAA AAATAACCAAAGGACTAATAACTAGAGAAACAATAAAATGAGAAACTAAAAAAAGAAATA AAGCATTGAAAATCTCATTAGACTAGTTGGCTCATTTCCATGGCAAAATGTACAATTGTA TCTCAGTAACGTTATACTCGCTCCCTTTTTAGGCCAATTTTATCCATTATTCTCATTCTA AAATAGCGGACATAACGAGAAAACGATTTACGTTAGAAGTGATAACAACTTTGGCGACCG GAATGCTGCATGAAAAATTATAACAAAAGGCCCCTCAAAAAGCTAAGGGACAGGGATGTT GCTGCAATTGGAATAGTATAATCGGCCGTCAAAATTATCAACTAATAGCATTGGCTACTC CAATTTGGACTTACTGGCTGGTAATTGACTTGTATAGCATTGTCTTAGCTTATTATTTTT TTTTTGCTGAAGAATAAGTAGGATAATTGAAGAAGAATAGCTAAGATAAAAAAAGATAGC TAGTGCATTCTGAAAACTTCAATTGCGTGGTACATACAAT
Chr coordinates	Chr XV from 486779-483219