Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name TCB1
Systematic Name YOR086C
Alias tricalbin
Strain S288c
Description Lipid-binding ER protein involved in ER-plasma membrane tethering; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to plasma membrane and regulate PI4P levels by controlling access of Sac1p phosphatase to its substrate PI4P in PM; contains 3 calcium and lipid binding domains; non-tagged protein also localizes to mitochondria; C-termini of Tcb1p, Tcb2p and Tcb3p interact; TCB1 has a paralog, TCB2, that arose from the whole genome duplication
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>TCB1 YOR086C
GAGATCCATTGTTTTCCGGCATGCACTGTTCGTTAGAAATTGGCAAGTGCAAGTCGCCGT
TGGCTGATACCATAATGCTCCTGTTCTAGTAATATTATATTTTATAACTGAATTCTATTG
CCTTACCAAGCCACTGATTAATGACAATTGCATTGAATAGGCTCTAGCTGATCCTCGAAG
GATACTGACTAAATTTACCACATATTTTCAGCTCTTATGAGATAACTCCGACATAGCAAC
AGTGTAGGAGAAAAATTAAAAAATTAACGACCCCAGTGAGGGTTGAACTCACGATCTTGC
GATTAACAGTCGCACGCCTTAACCAACTTGGCCATGGAGTCTAACTTTGTTGTTTTAGAG
AACGAATGAAGAACTTATTATGACGATAAAAATATGTCAAGAGAGGCCCAAGAATGTATA
AATCATTGTAAAACCAAGCAAGTAACAAAAATGGTCATGTGACAAGAGGTGGTGACATAA
AAATAACCAAAGGACTAATAACTAGAGAAACAATAAAATGAGAAACTAAAAAAAGAAATA
AAGCATTGAAAATCTCATTAGACTAGTTGGCTCATTTCCATGGCAAAATGTACAATTGTA
TCTCAGTAACGTTATACTCGCTCCCTTTTTAGGCCAATTTTATCCATTATTCTCATTCTA
AAATAGCGGACATAACGAGAAAACGATTTACGTTAGAAGTGATAACAACTTTGGCGACCG
GAATGCTGCATGAAAAATTATAACAAAAGGCCCCTCAAAAAGCTAAGGGACAGGGATGTT
GCTGCAATTGGAATAGTATAATCGGCCGTCAAAATTATCAACTAATAGCATTGGCTACTC
CAATTTGGACTTACTGGCTGGTAATTGACTTGTATAGCATTGTCTTAGCTTATTATTTTT
TTTTTGCTGAAGAATAAGTAGGATAATTGAAGAAGAATAGCTAAGATAAAAAAAGATAGC
TAGTGCATTCTGAAAACTTCAATTGCGTGGTACATACAAT
Chr coordinates Chr XV from 486779-483219
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