Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
VPS21 Systematic Name
YOR089C Alias
VPS12, VPT12, YPT21, YPT51 Strain
S288c Description
Endosomal Rab family GTPase; required for endocytic transport and sorting of vacuolar hydrolases; required for endosomal localization of the CORVET complex; required with YPT52 for MVB biogenesis and sorting; involved in autophagy and ionic stress tolerance; geranylgeranylation required for membrane association; protein abundance increases in response to DNA replication stress; mammalian Rab5 homolog; VPS21 has a paralog, YPT53, that arose from the whole genome duplication External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>VPS21 YOR089C
ATGAACACATCAGTCACTTCCATAAAGTTGGTACTGTTGGGTGAGGCAGCAGTTGGTAAA
TCGTCAATAGTCCTAAGGTTTGTATCTAATGATTTTGCCGAAAATAAGGAGCCCACCATT
GGTGCAGCATTCCTCACTCAAAGAGTTACTATAAATGAACATACTGTTAAGTTTGAAATA
TGGGACACTGCTGGGCAAGAGAGATTTGCATCTTTAGCACCTATGTACTATAGAAACGCA
CAAGCTGCTCTTGTAGTATACGACGTTACAAAACCACAATCCTTTATTAAAGCGCGCCAC
TGGGTTAAGGAATTACATGAACAGGCATCAAAGGATATCATCATTGCGTTAGTTGGTAAC
AAGATCGATATGCTGCAAGAAGGTGGGGAAAGAAAAGTCGCAAGGGAAGAAGGTGAAAAG
CTAGCGGAAGAAAAGGGCTTGTTGTTCTTTGAAACAAGTGCAAAGACAGGAGAGAATGTT
AACGATGTATTTTTGGGAATCGGTGAAAAGATACCACTGAAGACGGCTGAAGAGCAAAAT
AGTGCAAGTAACGAACGTGAGTCGAACAATCAAAGAGTGGATTTGAACGCTGCTAATGAT
GGGACCAGCGCAAACAGTGCTTGCAGTTGTTAG Promoter Sequence
Download FASTA
>VPS21 YOR089C
AGAACATCCAGGAGAACCAAACGTTATAAGAAACGGAAGAATATTGGGTTCATTACAACC
ATCCAGGGCATTTGGAGACTATCGCTACAAGATCAAAGAAGTCGATGGAAAACCATTATC
GGATTTGCCTGAAGTTGCCAAACTTTATTTTAGAAGAGAGCCAAGGGATTTCAAGACACC
CCCATATGTCACTGCGGAACCAGTGATTACTTCTGCCAAAATTGGTGAGAACACTAAATT
TATGGTGATGGGTTCGGATGGTTTATTCGAATTACTAACTAATGAAGAAATTGCTTCCTT
GGTTATCAGGTGGATGGATAAAAATATGAATCTGGCACCTGTGAAGGCAGAACCGGGGAA
ATTACCAAAAGTTATCGATGTATCTGAAGACAAGGAAGCACAAAGACCGGCATTCAGGTA
CAAGGATAATAATTCGAGCTCACCATCAGGATCAAACCCAGAGTATCTTATTGAAGACAA
AAACGTCGCCACTCATTTAATTAGAAATGCATTAAGTGCGGGCGGAAGAAAAGAATATGT
ATCGGCATTGGTAAGTATACCATCGCCGATGAGTAGAAGATACAGAGATGACTTGACAGT
AACAGTGGCGTTCTTTGGTGATTCTGGAACACCCTCAATTGTCTCCAATGCTACTTCAAT
AGTTATGAACCCGGAGGCAACAACAAAGCCAAAACCTAGATTATGACGATATAAACTTAT
GCTGAGGTAGGTATATACCAGAGGATTTATTTTATAGATATTAGTCTGCTGATTATCTAG
TTTCTTGTCACCTCATACGTGTTTTTTTTTTTTTTGGTTTTCTCGGTTTGCATTATGGGG
CTTTTTGCTAAAACAATATCCCCGAAAAGACAAAGAAAGAGAAGTGAGGTGAAAATACGA
GCAGCTTATCTTATAAAAGTGGCAACGATTTTAAAAATAAAAAGCAAGATCGTCGACTTA
TCTAAGCTATAAAAAAATATCCCTTTTATCACACAAAAAA
Chr coordinates
Chr XV from 490828-490196
