S.cerevisiae - Yeastract

Locus Information

Standard Name	LAS17
Systematic Name	YOR181W
Alias	BEE1
Strain	S288c
Description	Actin assembly factor; C-terminal WCA domain activates Arp2/3 complex-mediated nucleation of branched actin filaments, polyproline domain nucleates actin filaments independent of Arp2/3; mutants are defective in endocytosis, bud site selection, cytokinesis; human homolog WAS (Wiskott-Aldrich Syndrome) implicated in severe immunodeficiency; human WAS complements yeast null mutant, but only in presence of WIPF1, which mediates localization of WAS to cortical patches
External sources	Open in SGD Open in KEGG

Gene Sequence Download FASTA View Seq	Sequence hidden
Promoter Sequence Download FASTA	>LAS17 YOR181W CGTCTCCATCGTTTAGCTTGTTAACTGCTGAAAACTTACCTCCCGAGGAGAAATACTTGC CTGAGCTTTGTAGAACAGTAAACAAAACAGAATCAATATCGTTTGCCTTATGCAGTAATA GTGCAATGTATACAAAATCCTCGAAAGTTAAAGAGTTCAAATGTTTTGGATCAATTAATT TGATTATGAAAAAGGGACCATTAATATGGTAGCACACACGACTGCTCATAGTTAGAAGAT AACTCACTAGACTTAACACCAGAAAATCCTACTCTGTAATAAAATAATCCCGGGGTAATG GATTGGATTTTTCTATCAGGATCGTTTACGTATATATAATACACTGTCGGAGTTTAGCGC GCTTACAGCCGCTACTTGTGGAGTCCTTTTTTTTTTTTTTTTTTTGGGGTTTCAGACATC CAGTAAAGAATAGAAACAAGCAACAAACTTCAGAACTGAAACAATGCTTTTTTAAGTTAT CGCCTAAATATATTCAAAAAATATAGATATGCTAGATTTTCAATTATACCAAAGTTCATA TTTTCAAAATGAATGTTAACAAAAAGACAAGTTGATGGCCCTTTTTCATAAAGTATGCGT TTAGTTTCAAGTAACGCCGGCTGACGTGGACGATTTATCAAAGAAGTGGTTTTGGAATAC TCTTCTTTTGCAATTAGAAAAAAGGCAAAACTAAATGCAATGCAAGCAGTTGCCCATGGT ACTTGAAATTGTGTCTCTGGTTTAAAAGATCTATGATATAAGTCTTAACTGATCTTATAG TTGTTTTTTTTTGAATTTTCCAAATAGTTTATATGATCATTGAATACGTGCGAGACGTCC GAAAAGGGGCCAGTCAATACCTATGAAAAAAAATCATGAATATGTAATAATAAATATTGA ATGTAGAATATACATAGTAGAAAAGGAAGTGCTGTAGCGATTGCCATCTCCGCTACAAAT TACAGTTCGTTACTTTAAGTGTTGATAGGCGTGATTTAAT
Chr coordinates	Chr XV from 675939-677840