Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
LAS17 Systematic Name
YOR181W Alias
BEE1 Strain
S288c Description
Actin assembly factor; C-terminal WCA domain activates Arp2/3 complex-mediated nucleation of branched actin filaments, polyproline domain nucleates actin filaments independent of Arp2/3; mutants are defective in endocytosis, bud site selection, cytokinesis; human homolog WAS (Wiskott-Aldrich Syndrome) implicated in severe immunodeficiency; human WAS complements yeast null mutant, but only in presence of WIPF1, which mediates localization of WAS to cortical patches External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>LAS17 YOR181W
ATGGGACTCCTAAACTCTTCAGATAAGGAAATTATCAAAAGGGCTCTACCAAAAGCGTCG
AATAAGATTATTGATGTTACGGTGGCTCGACTATACATTGCATACCCTGATAAAAATGAA
TGGCAGTACACTGGACTTTCAGGAGCTCTTGCTCTAGTAGACGATCTTGTGGGGAATACT
TTTTTTTTGAAATTAGTTGACATCAATGGCCATAGAGGAGTTATCTGGGACCAAGAATTG
TATGTGAATTTTGAATACTATCAAGACCGTACTTTTTTTCATACATTTGAGATGGAAGAA
TGCTTTGCAGGTTTATTGTTTGTAGATATTAATGAAGCATCGCACTTTTTAAAGAGAGTT
CAAAAGCGTGAAAGATATGCTAACAGGAAAACTTTGTTGAACAAAAATGCTGTAGCATTA
ACCAAGAAAGTAAGAGAAGAACAAAAATCTCAAGTGGTGCACGGCCCAAGAGGGGAGTCA
TTGATTGACAATCAAAGGAAAAGATATAATTATGAAGATGTGGACACAATTCCAACTACA
AAGCATAAGGCTCCTCCCCCTCCTCCGCCAACGGCCGAAACATTTGATTCAGACCAAACA
AGTTCATTTTCCGATATCAATTCGACAACAGCATCCGCACCGACTACCCCAGCCCCTGCT
CTTCCTCCTGCATCTCCTGAAGTAAGAAAAGAAGAAACGCATCCAAAGCATAGTTTACCG
CCTTTACCAAATCAGTTTGCGCCATTACCAGACCCTCCACAACATAACTCTCCACCTCAA
AATAACGCGCCTTCGCAACCCCAAAGCAATCCATTTCCATTCCCAATTCCTGAAATTCCC
TCGACACAGTCTGCAACAAACCCATTTCCATTTCCGGTACCTCAGCAGCAGTTTAATCAA
GCTCCTTCAATGGGCATACCACAGCAGAATAGGCCCCTTCCACAGTTGCCTAACAGAAAT
AATCGGCCTGTGCCACCTCCTCCGCCAATGCGTACCACTACTGAAGGTTCAGGTGTTCGC
CTACCTGCTCCTCCACCTCCGCCAAGGCGTGGGCCAGCACCACCGCCTCCACCACATAGG
CACGTAACCAGTAATACCCTGAATTCTGCCGGTGGAAATAGCCTCCTTCCACAGGCCACT
GGAAGAAGAGGGCCAGCACCACCACCTCCTCCAAGAGCATCTCGCCCCACACCAAACGTT
ACGATGCAACAAAATCCACAACAGTACAATAATTCTAACCGCCCCTTTGGATATCAGACA
AATAGCAACATGTCATCTCCACCCCCTCCTCCAGTGACAACTTTCAATACCCTGACACCA
CAAATGACTGCAGCAACTGGACAACCTGCAGTTCCCCTTCCTCAGAATACTCAAGCACCT
TCGCAAGCCACAAATGTGCCAGTGGCACCACCACCTCCTCCGGCATCTTTAGGCCAGTCG
CAGATACCTCAGTCAGCACCCTCAGCACCTATTCCGCCAACGTTACCATCGACGACGAGT
GCTGCACCACCTCCGCCACCAGCATTCCTAACTCAACAACCTCAATCTGGAGGAGCTCCA
GCTCCACCCCCACCTCCTCAAATGCCAGCTACATCAACATCCGGAGGCGGTTCATTCGCT
GAAACTACTGGAGATGCAGGTCGTGATGCACTTTTAGCTTCAATTAGAGGGGCAGGTGGC
ATAGGCGCTTTGAGAAAAGTTGACAAATCGCAGCTAGATAAGCCCTCAGTTTTACTGCAG
GAAGCACGTGGAGAATCTGCTTCACCACCAGCAGCGGCTGGAAATGGAGGCACACCTGGT
GGACCTCCGGCTTCTTTAGCAGATGCGTTGGCAGCAGCTTTAAACAAAAGAAAAACTAAA
GTGGGAGCTCATGACGATATGGACAATGGTGATGATTGGTAA Promoter Sequence
Download FASTA
>LAS17 YOR181W
CGTCTCCATCGTTTAGCTTGTTAACTGCTGAAAACTTACCTCCCGAGGAGAAATACTTGC
CTGAGCTTTGTAGAACAGTAAACAAAACAGAATCAATATCGTTTGCCTTATGCAGTAATA
GTGCAATGTATACAAAATCCTCGAAAGTTAAAGAGTTCAAATGTTTTGGATCAATTAATT
TGATTATGAAAAAGGGACCATTAATATGGTAGCACACACGACTGCTCATAGTTAGAAGAT
AACTCACTAGACTTAACACCAGAAAATCCTACTCTGTAATAAAATAATCCCGGGGTAATG
GATTGGATTTTTCTATCAGGATCGTTTACGTATATATAATACACTGTCGGAGTTTAGCGC
GCTTACAGCCGCTACTTGTGGAGTCCTTTTTTTTTTTTTTTTTTTGGGGTTTCAGACATC
CAGTAAAGAATAGAAACAAGCAACAAACTTCAGAACTGAAACAATGCTTTTTTAAGTTAT
CGCCTAAATATATTCAAAAAATATAGATATGCTAGATTTTCAATTATACCAAAGTTCATA
TTTTCAAAATGAATGTTAACAAAAAGACAAGTTGATGGCCCTTTTTCATAAAGTATGCGT
TTAGTTTCAAGTAACGCCGGCTGACGTGGACGATTTATCAAAGAAGTGGTTTTGGAATAC
TCTTCTTTTGCAATTAGAAAAAAGGCAAAACTAAATGCAATGCAAGCAGTTGCCCATGGT
ACTTGAAATTGTGTCTCTGGTTTAAAAGATCTATGATATAAGTCTTAACTGATCTTATAG
TTGTTTTTTTTTGAATTTTCCAAATAGTTTATATGATCATTGAATACGTGCGAGACGTCC
GAAAAGGGGCCAGTCAATACCTATGAAAAAAAATCATGAATATGTAATAATAAATATTGA
ATGTAGAATATACATAGTAGAAAAGGAAGTGCTGTAGCGATTGCCATCTCCGCTACAAAT
TACAGTTCGTTACTTTAAGTGTTGATAGGCGTGATTTAAT
Chr coordinates
Chr XV from 675939-677840
