Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
MCA1
Systematic Name
YOR197W
Alias
YCA1
Strain
S288c
Description
Ca2+-dependent cysteine protease; may cleave specific substrates during the stress response; regulates apoptosis upon H2O2 treatment; required for clearance of insoluble protein aggregates during normal growth; implicated in cell cycle dynamics and lifespan extension; undergoes autocatalytic processing; similar to mammalian metacaspases, but exists as a monomer due to an extra pair of anti-parallel beta-strands that block potential dimerization
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>MCA1 YOR197W
ATGTATCCAGGTAGTGGACGTTACACCTACAACAACGCTGGTGGTAATAATGGCTACCAA
CGGCCCATGGCTCCTCCACCTAACCAGCAGTATGGACAGCAATATGGTCAGCAATATGAA
CAGCAGTATGGACAGCAATATGGGCAACAAAATGATCAGCAATTCAGTCAGCAATATGCT
CCACCACCAGGTCCTCCCCCTATGGCTTATAACAGGCCTGTGTATCCCCCCCCTCAATTC
CAGCAGGAACAGGCAAAGGCACAATTAAGCAACGGCTACAACAATCCTAATGTAAACGCA
TCCAATATGTACGGTCCACCCCAGAATATGTCATTACCTCCACCTCAAACACAAACTATT
CAAGGTACAGACCAACCTTATCAGTATTCTCAATGTACTGGGCGTAGAAAGGCTTTGATT
ATCGGTATAAACTACATAGGTTCAAAAAATCAACTGCGTGGTTGTATCAATGATGCTCAT
AACATCTTCAACTTTTTGACTAATGGGTACGGTTACAGTTCAGATGACATTGTCATATTA
ACTGATGATCAGAACGATTTGGTCAGGGTTCCCACTAGGGCTAATATGATTAGGGCCATG
CAATGGTTGGTCAAGGATGCGCAACCCAATGATTCTTTGTTCCTTCATTATTCTGGACAT
GGTGGCCAAACTGAAGATTTGGATGGGGACGAAGAAGATGGGATGGATGATGTTATATAT
CCGGTCGATTTCGAAACTCAAGGGCCAATTATCGACGATGAAATGCACGATATAATGGTG
AAGCCCTTACAACAAGGTGTTAGACTAACAGCATTGTTTGACTCTTGTCATTCGGGTACA
GTGTTGGATCTTCCATATACCTATTCTACTAAGGGTATTATTAAGGAGCCCAATATTTGG
AAGGATGTTGGCCAAGATGGCCTGCAAGCAGCTATTTCATATGCCACAGGAAACAGGGCT
GCTTTGATTGGTTCTTTAGGTTCTATATTCAAGACCGTTAAGGGAGGTATGGGCAATAAT
GTGGATAGAGAACGCGTGAGACAGATCAAATTCTCAGCAGCAGATGTTGTTATGTTATCA
GGTTCGAAGGATAATCAAACTTCTGCAGATGCTGTCGAAGATGGGCAAAATACAGGTGCA
ATGTCCCACGCCTTCATCAAGGTTATGACTTTACAACCACAGCAATCATATTTATCTCTT
TTACAGAACATGAGGAAAGAATTGGCTGGTAAGTATTCTCAAAAACCACAATTATCATCG
TCACACCCTATTGACGTAAATCTGCAATTTATTATGTAG
Promoter Sequence
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>MCA1 YOR197W
GTATTTGGTGCCTTCTGTTTGATTTTGCGAACCGTCTCGGCCAGGTGATTAGCACCACCA
TCGACTAAATCGTCCCTATCAACGGTAGTTAAAACAACATAACCCAACCCCCATCTTTTG
ATAGCTTCGGCAGTATTTTCGGGCTCCATTGGGTCCGGCTTACTAGGCGTTCTATTGGTC
TTCACAGAACAAAACCTACATCCACGAGTGCAAGTATCACCAAGCAGCATAATTGTTGCC
GTTGCCTTAGATTTATCTTTGCCTCCCCAACATTCACCAATATTGGGACATCTTGCCTCC
TCACAAACAGTACTCAGGCCTAATTCTTTTACGTCGCCTTTCAATTTATGGTAATTGGTA
CCCTTAGGAATAGGAACCTTAAGCCAACGAGGTAGTTTTTTAGCTTCCTCTGTATTTTGC
CTTGCCTTCTCCAGAGGGTCCAAGATCATTTTCGAAGCTTTACCTGAAACAAAATCTGCA
AAAGATGGACCCAAATTAAGAGCATCTTTGAACTCTGTAATTCTTTTTCTGTTCCCCTTG
CGTCTTTTTCCCGAAGTCCCTGTTAACTGACTGGTTGCATTTTCAACCTCAGTTGAATTT
CCAACTGGTACCCTAACGCTAGCGTTATCTGAATCAGTATTCAATGCATTGGATCTTATT
GGCCGAGTTGCGCTCGTTCCACACCTAATAGTGGACGAAATCCATCTTGTATTTCTCCCA
ACAAATAGTACTCCAACAGATCGTCTATACATTATTGTGGCTTAACAGTTCTCCTTAAAA
TCCACATAACTGACAAAACTGGATACTTAATGCCCATCGAGTCATATACATATATTTGAT
TACTACAAGTGCTTTTCAAATAACTGCTTCGAGAAAAGCGTCCGGGTAATAACAACTATT
GAAAAAGCATGGCTTCGCATTAATAGGAGCCAAAAATATGAAGATGAGCCTCGAAGTTTA
TCTAAACTACCACCAAAGAAGACCGACTAGATTTACAATC
Chr coordinates
Chr XV from 717086-718384