Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
DED1
Systematic Name
YOR204W
Alias
SPP81
Strain
S288c
Description
ATP-dependent DEAD-box RNA helicase with strand-annealing activity; promotes eIF4F-dependent 48S translation preinitiation complex (PIC) assembly, stimulating recruitment of mRNAs with long, structured 5'-UTRs; cooperates with Dbp1p in PIC attachment and scanning; ATPase activity stimulated by mRNA cap-associated factor binding; directly binds eIF4G; role in spliceosomal complex disassembly; mutation in human homolog DBY associated with male infertility; human homolog DDX3X complements the null
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>DED1 YOR204W
ATGGCTGAACTGAGCGAACAAGTGCAAAATTTAAGCATCAACGACAACAACGAGAATGGT
TATGTTCCTCCTCACTTAAGAGGAAAACCAAGAAGTGCCAGAAATAACAGTAGCAACTAC
AATAACAACAACGGCGGCTACAACGGTGGCCGTGGCGGTGGCAGCTTCTTTAGCAACAAC
CGTCGTGGTGGTTACGGCAACGGTGGTTTCTTCGGTGGAAACAACGGTGGCAGCAGATCT
AACGGCCGTTCTGGTGGTAGATGGATCGATGGCAAACATGTCCCAGCTCCAAGAAACGAA
AAGGCCGAGATCGCCATATTTGGTGTCCCCGAGGATCCAAATTTCCAATCTTCTGGTATT
AACTTCGATAACTACGATGATATTCCAGTGGACGCCTCTGGTAAGGATGTTCCTGAACCA
ATCACAGAATTTACCTCACCTCCATTGGACGGATTGTTATTGGAAAACATCAAATTGGCC
CGTTTCACCAAGCCAACACCTGTGCAAAAATACTCCGTCCCTATCGTTGCCAACGGCAGA
GATTTGATGGCCTGTGCGCAGACCGGTTCTGGTAAGACTGGTGGGTTTTTATTCCCAGTG
TTGTCCGAATCATTTAAGACTGGACCATCTCCTCAACCAGAGTCTCAAGGCTCCTTTTAC
CAAAGAAAGGCCTACCCAACTGCTGTCATTATGGCTCCAACTAGAGAGTTGGCCACCCAA
ATTTTCGATGAAGCCAAGAAATTTACTTATAGATCCTGGGTCAAGGCCTGCGTCGTCTAC
GGTGGTTCTCCAATTGGTAACCAACTAAGAGAAATTGAACGTGGTTGCGATCTTTTAGTC
GCTACTCCAGGTCGTTTGAATGACTTGTTGGAACGTGGTAAAATTTCTTTGGCCAACGTC
AAGTATTTGGTTCTAGATGAAGCTGATAGAATGTTGGATATGGGTTTCGAACCTCAAATT
AGACATATTGTCGAAGACTGTGATATGACTCCTGTTGGTGAAAGACAAACTCTGATGTTC
TCAGCTACTTTTCCCGCTGATATCCAACATTTGGCCCGTGATTTCTTAAGTGACTACATC
TTTTTGTCTGTTGGTAGAGTCGGTTCTACTTCAGAAAACATTACTCAAAAAGTCTTATAC
GTTGAAAATCAAGATAAGAAGTCAGCCTTATTGGATCTATTGTCTGCATCCACTGACGGT
TTGACTTTGATCTTTGTCGAAACTAAGAGAATGGCAGATCAATTGACCGATTTCCTGATC
ATGCAAAACTTTAGAGCTACCGCCATTCATGGTGACCGTACCCAATCTGAGAGAGAACGT
GCCTTGGCCGCCTTCAGATCTGGTGCCGCTACTTTATTGGTTGCCACAGCTGTCGCAGCT
AGAGGTCTAGATATTCCAAACGTCACCCACGTTATCAACTACGATTTACCAAGTGATGTC
GATGATTACGTCCATAGAATTGGTAGAACTGGTCGTGCCGGTAACACCGGTCTTGCCACT
GCCTTTTTCAACAGTGAAAACAGTAACATTGTTAAAGGTTTGCATGAAATTTTGACTGAA
GCTAACCAAGAAGTCCCATCATTCTTGAAGGACGCTATGATGAGTGCTCCAGGTAGCAGA
AGCAACAGCCGTAGAGGCGGTTTCGGTCGCAACAACAACAGAGATTACCGTAAGGCCGGA
GGCGCTAGCGCAGGCGGCTGGGGCTCTTCAAGAAGCAGAGATAACTCTTTCAGAGGCGGT
AGTGGCTGGGGTAGCGATTCCAAGTCTTCTGGCTGGGGTAACAGCGGTGGTTCAAACAAC
TCTTCTTGGTGGTGA
Promoter Sequence
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>DED1 YOR204W
TAAAAAATGAGCAGGCAAGATAAACGAAGGCAAAGATGACAGAGCAGAAAGCCCTAGTAA
AGCGTATTACAAATGAAACCAAGATTCAGATTGCGATCTCTTTAAAGGGTGGTCCCCTAG
CGATAGAGCACTCGATCTTCCCAGAAAAAGAGGCAGAAGCAGTAGCAGAACAGGCCACAC
AATCGCAAGTGATTAACGTCCACACAGGTATAGGGTTTCTGGACCATATGATACATGCTC
TGGCCAAGCATTCCGGCTGGTCGCTAATCGTTGAGTGCATTGGTGACTTACACATAGACG
ACCATCACACCACTGAAGACTGCGGGATTGCTCTCGGTCAAGCTTTTAAAGAGGCCCTAG
GGGCCGTGCGTGGAGTAAAAAGGTTTGGATCAGGATTTGCGCCTTTGGATGAGGCACTTT
CCAGAGCGGTGGTAGATCTTTCGAACAGGCCGTACGCAGTTGTCGAACTTGGTTTGCAAA
GGGAGAAAGTAGGAGATCTCTCTTGCGAGATGATCCCGCATTTTCTTGAAAGCTTTGCAG
AGGCTAGCAGAATTACCCTCCACGTTGATTGTCTGCGAGGCAAGAATGATCATCACCGTA
GTGAGAGTGCGTTCAAGGCTCTTGCGGTTGCCATAAGAGAAGCCACCTCGCCCAATGGTA
CCAACGATGTTCCCTCCACCAAAGGTGTTCTTATGTAGTGACACCGATTATTTAAAGCTG
CAGCATACGATATATATACATGTGTATATATGTATACCTATGAATGTCAGTAAGTATGTA
TACGAACAGTATGATACTGAAGATGACAAGGTAATGCATCATTCTATACGTGTCATTCTG
AACGAGGCGCGCTTTCCTTTTTTCTTTTTGCTTTTTCTTTTTTTTTCTCTTGAACTCGAG
AAAAAAAATATAAAAGAGATGGAGGAACGGGAAAAAGTTAGTTGTGGTGATAGGTGGCAA
GTGGTATTCCGTAAGAACAACAAGAAAAGCATTTCATATT
Chr coordinates
Chr XV from 722911-724725