S.cerevisiae - Yeastract

Locus Information

Standard Name	ISU2
Systematic Name	YOR226C
Alias	NUA2
Strain	S288c
Description	Mitochondrial protein required for iron-sulfur protein synthesis; performs scaffolding function during Fe/S cluster assembly; involved in Fe-S cluster assembly for both mitochondrial and cytosolic proteins; protein abundance increases under DNA replication stress; ISU2 has a paralog, ISU1, that arose from the whole genome duplication; isu1 isu2 double mutant is inviable; human homolog ISCU implicated in mitochondrial myopathy, can complement isu1 isu2 double mutant
External sources	Open in SGD Open in KEGG

Gene Sequence Download FASTA View Seq	Sequence hidden
Promoter Sequence Download FASTA	>ISU2 YOR226C ACCTTCTCGGCGGATACTGCTGGTTTAGAGTTGGATAATTCGTTATTTACATTCTGGCCG CTCAGGGGCCTTTGAGGAGAAGCTATAGTTTTCGTAGGAACAGCTGCGGTTGATGGCAAA GTAGCAGTTTTCTTTACAGAGGTGGTGGTAGCTTCTGAAGTGCGCGTGGAAGCCGCACTT TTGGTCCTATTCCTTCGTTTCCCCTTATACAACCAGTCCAATGGCACATCTATATCAGTG TACTTCAACTTGGAGCTCATGTCAGACTAGATTCAACCAGATACAAATTAATACATATAC AATGGCCAAAGAGAATGAAGAAAAAAGGAAGGGACTCAGTCAAATATTAGACGACAGTAT CACTGAAGGAAGGGAACTGGTGCGAGGAGGAAAGGAGAAAATACGTAATGCAAGTGGTAA TAAAACGGGAACAGGCTAGTTCTCGAGAAATGTGGCAACTGCAACCAAATGGAAGAGTCA AATGTAAGTTATAGAGGGTTCGCTTTCCACCTTAACCCATCGAACTGTCAATCATGTCGC TTCTTTAACCTGCCCCTTAACGTTACTAAGCAAAAACAAAAGGCAGACAAACTCAAGAAA TAATTAAGCATAACCCGGAAAAGGAAACGCCAAACCACTATGGAATTATTCTTATTTCAT TACAGGGTCCGCACCTTCCCAGTCTAGAAAGGCATGGTATGGAATTATGACTGCAACTTT ATAGTGGTCAGATGTTTATATATGTACACCCATAATACAGATACACAGCATACTGCATAT ATCCGAGTCACCATGATTCTATTGTTTCAGAGTCCGGTTCAGGCCCAACGTTTTTTGGCG CCCTCGTTTTTTCCCTATGCGGAACCTACTATTAATAAGCACCTGGGGCCGGCCGGTGCA GCAGTATAGCAGTATATAACAACAGCAAAAGAAGCATATGTAGACAACGCTGAGGTTTCA TTACAGCTCATACATCACCAACAAACATAGCACAGCATAG
Chr coordinates	Chr XV from 762084-761614