Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
ISU2 Systematic Name
YOR226C Alias
NUA2 Strain
S288c Description
Mitochondrial protein required for iron-sulfur protein synthesis; performs scaffolding function during Fe/S cluster assembly; involved in Fe-S cluster assembly for both mitochondrial and cytosolic proteins; protein abundance increases under DNA replication stress; ISU2 has a paralog, ISU1, that arose from the whole genome duplication; isu1 isu2 double mutant is inviable; human homolog ISCU implicated in mitochondrial myopathy, can complement isu1 isu2 double mutant External sources
Open in SGD
Open in KEGG
Gene Sequence
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>ISU2 YOR226C
ATGTTCGCCAGACTCGCTAATCCTGCCCACTTCAAGCCTCTCACGGGCTCCCACATAACA
AGAGCTGCCAAAAGACTTTACCATCCTAAGGTAATTGACCACTACACAAACCCAAGAAAC
GTTGGGTCCATGGATAAGTCCTTAGCTAATGTCGGCACAGGAATCGTGGGCGCCCCTGCG
TGTGGTGATGTGATAAAACTACAAATACAGGTGAATGATAAATCGGGTATTATCGAGAAC
GTTAAGTTCAAGACCTTCGGGTGTGGGTCTGCCATCGCTTCCTCCTCCTACATGACCGAG
CTGGTACGCGGTATGTCACTTGATGAGGCCGTTAAAATTAAAAACACGGAAATCGCGAAG
GAGCTAAGTCTTCCTCCAGTAAAACTGCATTGTTCCATGCTTGCAGAAGACGCTATCAAG
GCGGCAATCAAGGACTACAAAACAAAGAGGAACCCCTCCGTTTTGCATTGA Promoter Sequence
Download FASTA
>ISU2 YOR226C
ACCTTCTCGGCGGATACTGCTGGTTTAGAGTTGGATAATTCGTTATTTACATTCTGGCCG
CTCAGGGGCCTTTGAGGAGAAGCTATAGTTTTCGTAGGAACAGCTGCGGTTGATGGCAAA
GTAGCAGTTTTCTTTACAGAGGTGGTGGTAGCTTCTGAAGTGCGCGTGGAAGCCGCACTT
TTGGTCCTATTCCTTCGTTTCCCCTTATACAACCAGTCCAATGGCACATCTATATCAGTG
TACTTCAACTTGGAGCTCATGTCAGACTAGATTCAACCAGATACAAATTAATACATATAC
AATGGCCAAAGAGAATGAAGAAAAAAGGAAGGGACTCAGTCAAATATTAGACGACAGTAT
CACTGAAGGAAGGGAACTGGTGCGAGGAGGAAAGGAGAAAATACGTAATGCAAGTGGTAA
TAAAACGGGAACAGGCTAGTTCTCGAGAAATGTGGCAACTGCAACCAAATGGAAGAGTCA
AATGTAAGTTATAGAGGGTTCGCTTTCCACCTTAACCCATCGAACTGTCAATCATGTCGC
TTCTTTAACCTGCCCCTTAACGTTACTAAGCAAAAACAAAAGGCAGACAAACTCAAGAAA
TAATTAAGCATAACCCGGAAAAGGAAACGCCAAACCACTATGGAATTATTCTTATTTCAT
TACAGGGTCCGCACCTTCCCAGTCTAGAAAGGCATGGTATGGAATTATGACTGCAACTTT
ATAGTGGTCAGATGTTTATATATGTACACCCATAATACAGATACACAGCATACTGCATAT
ATCCGAGTCACCATGATTCTATTGTTTCAGAGTCCGGTTCAGGCCCAACGTTTTTTGGCG
CCCTCGTTTTTTCCCTATGCGGAACCTACTATTAATAAGCACCTGGGGCCGGCCGGTGCA
GCAGTATAGCAGTATATAACAACAGCAAAAGAAGCATATGTAGACAACGCTGAGGTTTCA
TTACAGCTCATACATCACCAACAAACATAGCACAGCATAG
Chr coordinates
Chr XV from 762084-761614
