Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
PAC1 Systematic Name
YOR269W Alias
LIS1 Strain
S288c Description
Regulator of dynein, involved in intracellular transport; part of the dynein/dynactin pathway; targets dynein to microtubule tips, which is necessary for sliding of microtubules along bud cortex; serves at interface between dynein's ATPase site and its microtubule binding stalk, causing individual dynein motors to remain attached to microtubules for long periods; synthetic lethal with bni1; homolog of human LIS1, mutations in which cause the severe brain disorder lissencephaly External sources
Open in SGD
Open in KEGG
Gene Sequence
Download FASTA Hide Seq
>PAC1 YOR269W
ATGACTAACTGGCAGCAACAGCTTCCTTTAACAGATACACAGAAAAATGAACTCGATAAA
AGTGTCCTCCGATATTTGAATTGGAATTACAAACAAACTGTACGACATGAGCATGCTCAA
GATTACGAAAGTGTTCGACATGCAATTGTAACTCTATCAGGTTTTCTGTTGCAAGAATCA
GTGGACCGGCAAGAATTCATCAGTAACAATGACACCAGTAACGAAAGTATGGTAGACATT
GATGAATTACTGCTACCGAAGAAGTGGAACTCAATTGTTAGACTACAAAAAAAAATCATT
GAATTGGAGCAGAATACAGAGACCCTTGTATCTCAGATTAAAGATTTGAACACTCAAGTG
TCAGAACTAGCACAATTCAAACCTACCACCAGTAACGGCACCAGCGCACATAATGTTTTG
AAATGGATACCGAGAAATCTACCAAGCTGTTTAATTAATGTTGAATCATCTGTCACTTCC
GTCAAACTACATCCCAATTTGCCTATAGTGTTTGTGGCCACAGATCATGGCAAATTATAC
GCATTTGATTTATTTAACTACACCATCCCTCTGGCATCCTTGCAAAGTCATACCAAGGCA
ATTACCTCCATGGATGTTTTATTTACCAATTATACGAACTCCAGCAAGAAGAACTATTTG
GTGATCGTTACCGCGTCTAAAGATTTGCAGATTCATGTTTTCAAGTGGGTCTCCGAGGAA
TGCAAGTTCCAACAAATTAGGTCTTTATTGGGCCATGAGCATATTGTCTCTGCGGTAAAA
ATCTGGCAGAAAAATAATGATGTCCATATAGCGTCCTGTTCCAGAGATCAAACTGTTAAA
ATTTGGGACTTCCACAATGGTTGGTCGTTGAAAACATTTCAGCCTCATTCCCAATGGGTT
CGTTCCATAGACGTTCTAGGCGATTACATCATCTCTGGTTCACATGACACTACATTAAGG
TTAACACATTGGCCATCAGGTAATGGTCTTAGTGTTGGCACGGGTCATGAATTTCCCATA
GAGAAAGTTAAATTTATTCATTTCATCGAAGACTCTCCGGAGATAAGGTTTAGAACACCA
TCAACGGATCGATATAAGAATTGGGGGATGCAATATTGTGTCTCAGCGTCAAGAGATAGA
ACGATAAAAATCTGGGAGATACCTCTACCTACGTTAATGGCCCATAGAGCACCCATACCG
AATCCTACAGATTCAAATTTCAGATGTGTTCTTACGTTGAAGGGGCATCTTTCGTGGGTT
AGAGATATTAGTATTCGAGGCCAATACTTGTTTTCTTGTGCTGATGATAAATCTGTCAGA
TGTTGGGATCTGAACACGGGGCAGTGCTTACACGTTTGGGAAAAGTTGCATACAGGATTT
GTCAACTGTTTAGACCTGGATGTGGATTTCGATTCTAACGTTACCCCAAGGCAAATGATG
GTCACTGGTGGATTGGATTGCAAGTCTAACGTTTTCATGAGATAA Promoter Sequence
Download FASTA
>PAC1 YOR269W
GGGGCGGCGACGACGTAGGGGTCAGGTAGAAGAGTTGGGCACTTATTGGCGATATAAAAG
ACAAAATACACTAATGCAAGAGTATGGTGAGCGAAAGGAAAATAAAGAAAGGCTACGTTA
TTGACGGATATATGAATCAAGACACAAGACTATTTTGTATAGTAAGCAGAACCGGCTTGT
GTTTGTGATTCATGGATCAACGAGACGGTAGCGAATAAGCACCAACGGAAAAAAAGAAAA
CATACGCATACATGCACGTACAAGATAAAAAAAGCACAGGTGTGGTGGTAGTATTGGGAT
AACCAGGCACACGCTACTGCGAGATAGCAAAAGACCCTTCCCGTAAACCGCTCGGATAAA
CCGATTTTGTCCTTTAGCGTGACACGGATTATACGCGGGGATCCGGCGTCACAAGCCACG
GCCCGTCCCGTCCGCGTGGTTTTTAATTCTGGCTCCGCGTAGTACATTTTGTAGCTTGCC
TTTTTTCCGGCTTCTAGAAAACTGGAAAAACCATAAGAAAAAAATGGGAAGGGGAAAACA
AAAACCATTCAGGTCTTGCGTGCCGAGAATTTTTTTTTTCTCTTTTTCGTTGTCAACTTT
TGCAGTAGCAGCCGCTGGCGACCCGGACGGTAGCCATGGCAACGGTTAGCTAATGGTAGG
TAAATAAAACGAGTAACGACGTTTTAGTATATCTTGGTAAACTACAATTAGATCTTAAAA
CGGTTCCTGAAAAAGTGCTTTCATCTACCATTGAATTTAATTCACTTCCCTTTATGGAAT
TTGCACTGGTTTTGTGCTGTGGGATGTGGGTGTTTTGAAATATTTTCAGCTTGCAAGTCG
TGCATATTGCACTTGTTTCTTATTTTTGGCGAGTGTAAACGTAATAGGTAATCTTAGTAT
TGGGCCATCGTCGCCCAGATAGCCATTGATAAAGCAGCTAGGTTCGTCGTCCGGTTGTTG
GTATACACCTGTGCGTGCGTAAGTGTAGAAAAAAATAGAA
Chr coordinates
Chr XV from 826385-827869
