Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
MIP1
Systematic Name
YOR330C
Strain
S288c
Description
Mitochondrial DNA polymerase gamma; single subunit of mitochondrial DNA polymerase in yeast, in contrast to metazoan complex of catalytic and accessory subunits; polymorphic in yeast, petites occur more frequently in some lab strains; human ortholog POLG complements yeast mip1 mutant; mutations in human POLG associated with Alpers-Huttenlocher syndrome (AHS), progressive external ophthalmoplegia (PEO), parkinsonism, other mitochondrial diseases
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>MIP1 YOR330C
ATGACGAAATTGATGGTTAGATCTGAATGCATGCTGCGAATGGTGCGGCGGCGGCCGCTG
CGTGTGCAGTTTTGTGCTCGATGGTTCTCCACAAAGAAGAATACCGCAGAAGCACCCAGG
ATTAATCCTGTGGGGATACAGTATTTAGGTGAGTCTTTGCAAAGACAGGTATTTGGTAGT
TGCGGTGGTAAAGATGAGGTGGAGCAAAGCGACAAACTTATGGAGTTATCGAAAAAGTCG
CTAAAGGACCATGGGTTGTGGGGGAAGAAGACGCTCATCACGGATCCAATATCGTTTCCT
CTGCCGCCACTACAAGGCAGGTCGCTAGATGAGCATTTCCAGAAGATTGGGCGTTTCAAT
TCTGAACCGTACAAGAGTTTTTGCGAGGACAAGTTCACGGAGATGGTGGCACGACCGGCG
GAATGGCTGCGGAAGCCAGGCTGGGTTAAATACGTACCTGGAATGGCACCCGTCGAAGTG
GCATACCCAGACGAAGAGCTGGTGGTGTTTGATGTAGAAACACTCTATAACGTCTCTGAC
TATCCGACTTTGGCCACGGCCTTGTCATCGACGGCGTGGTACCTTTGGTGTTCGCCGTTC
ATATGTGGTGGTGATGATCCTGCTGCACTGATACCCCTAAACACATTGAATAAAGAGCAA
GTAATAATTGGTCACAATGTTGCGTATGATAGGGCACGGGTTCTCGAAGAATACAACTTC
AGGGACTCGAAGGCGTTTTTCCTCGACACTCAATCTCTGCATATTGCATCTTTCGGGCTG
TGTTCAAGACAACGTCCGATGTTCATGAAGAATAACAAGAAAAAAGAGGCAGAAGTGGAA
TCGGAAGTACATCCAGAAATTTCCATAGAAGATTATGACGACCCTTGGTTAAATGTGTCT
GCTTTAAACTCGCTAAAGGATGTAGCGAAATTTCACTGCAAGATAGATCTTGATAAGACT
GATAGAGATTTCTTTGCTTCCACAGATAAATCAACGATAATAGAAAATTTCCAAAAACTG
GTCAACTACTGCGCCACTGACGTAACGGCCACAAGCCAAGTGTTTGATGAGATTTTCCCT
GTTTTCCTGAAAAAGTGTCCTCATCCAGTTTCGTTTGCAGGTTTAAAGTCCTTAAGCAAA
TGCATTCTGCCGACGAAGCTAAACGACTGGAATGATTACTTGAACAGCTCTGAGTCTTTG
TACCAACAGTCCAAAGTCCAGATAGAATCCAAAATTGTTCAAATCATAAAAGATATCGTC
CTGTTGAAGGACAAACCAGATTTTTATCTCAAGGATCCCTGGTTATCACAATTGGATTGG
ACCACCAAACCTTTAAGATTGACAAAGAAAGGTGTTCCTGCAAAGTGTCAAAAGCTGCCC
GGCTTTCCAGAATGGTATAGACAACTTTTTCCCTCAAAGGACACTGTAGAACCTAAGATC
ACTATTAAATCAAGAATAATTCCGATTTTGTTCAAGTTATCGTGGGAGAATTCCCCCGTA
ATATGGTCGAAGGAGTCTGGATGGTGCTTCAACGTGCCCCATGAACAAGTAGAAACATAC
AAGGCTAAAAATTATGTTTTGGCAGATAGCGTATCTCAAGAGGAAGAGGAAATAAGAACG
CATAACCTAGGATTGCAATGCACAGGTGTTCTTTTCAAAGTACCTCATCCCAATGGGCCG
ACTTTTAATTGCACTAATCTTTTAACCAAATCGTATAACCATTTTTTTGAAAAGGGCGTA
CTAAAATCTGAGTCAGAATTGGCTCATCAGGCTTTACAAATTAACTCTTCAGGGTCTTAT
TGGATGTCAGCAAGGGAAAGAATCCAATCCCAATTTGTAGTCCCCAGTTGTAAATTCCCT
AATGAGTTCCAGTCTTTGTCCGCAAAATCGTCGTTAAATAATGAGAAGACAAATGATCTT
GCCATAATTATACCGAAAATCGTCCCCATGGGCACAATCACTAGAAGAGCTGTGGAAAAT
GCGTGGTTAACCGCATCCAATGCAAAAGCAAATAGGATAGGTTCCGAATTGAAAACTCAA
GTCAAAGCTCCTCCAGGTTATTGTTTTGTTGGGGCGGACGTGGATAGTGAGGAATTGTGG
ATAGCATCTTTAGTCGGTGACTCCATTTTCAATGTTCATGGTGGTACCGCCATTGGTTGG
ATGTGTTTAGAAGGCACTAAAAACGAAGGTACAGATTTGCACACGAAGACTGCTCAAATT
TTGGGGTGTTCTCGTAATGAGGCGAAAATTTTTAATTATGGTAGAATTTACGGCGCTGGT
GCTAAATTTGCGAGTCAGTTACTTAAAAGGTTTAACCCATCTCTAACTGATGAAGAGACA
AAAAAAATTGCGAATAAGTTATATGAAAATACGAAAGGTAAAACGAAAAGATCAAAATTA
TTCAAAAAATTTTGGTATGGTGGATCTGAGTCAATTCTATTCAATAAATTAGAAAGCATC
GCGGAACAAGAAACTCCAAAGACACCGGTACTGGGATGTGGTATTACCTATTCACTTATG
AAGAAAAATCTGAGGGCGAATTCCTTTCTACCTTCAAGAATCAATTGGGCCATCCAGTCA
TCTGGAGTGGATTATCTACATCTTCTTTGTTGCTCCATGGAATATATTATTAAGAAATAT
AACCTTGAGGCAAGGCTTTGCATTTCCATCCATGATGAGATTAGATTTTTGGTGAGCGAA
AAGGACAAATACAGAGCTGCTATGGCTTTGCAAATCAGCAACATATGGACGAGAGCAATG
TTTTGCCAGCAAATGGGGATAAATGAATTACCGCAAAACTGTGCCTTTTTCTCGCAAGTA
GATATTGATTCTGTCATACGTAAAGAAGTCAATATGGACTGCATAACCCCCTCGAACAAA
ACCGCCATTCCTCATGGGGAGGCGCTTGATATCAATCAACTGCTAGACAAATCCAATAGT
AAATTGGGTAAACCAAATCTCGATATCGACAGCAAAGTATCACAATATGCCTATAACTAC
AGAGAACCTGTATTTGAAGAATATAATAAATCTTATACTCCAGAGTTCTTAAAATATTTT
CTTGCGATGCAAGTCCAGTCAGATAAGCGCGATGTGAATCGGCTAGAAGATGAGTATCTG
CGGGAGTGTACATCCAAAGAATACGCTAGAGATGGGAACACTGCAGAGTACAGCCTCCTA
GACTATATAAAGGATGTCGAGAAGGGCAAAAGGACTAAAGTACGTATTATGGGATCCAAT
TTTTTAGATGGTACCAAAAATGCCAAAGCTGATCAACGAATCAGATTACCTGTCAATATG
CCAGATTATCCCACACTTCATAAAATTGCTAACGATTCAGCAATCCCAGAAAAGCAATTG
CTGGAGAACAGGAGAAAGAAGGAAAACAGGATAGATGACGAAAATAAGAAAAAATTAACC
AGAAAAAAGAATACCACGCCTATGGAAAGGAAGTACAAAAGAGTGTATGGTGGCAGGAAG
GCATTTGAAGCGTTCTATGAATGTGCAAATAAACCGTTAGACTATACTTTGGAGACAGAA
AAACAATTCTTTAATATTCCTATAGATGGAGTGATTGACGACGTTCTGAACGACAAATCT
AATTATAAAAAGAAACCATCACAAGCAAGAACGGCATCATCATCGCCAATAAGAAAGACT
GCGAAAGCAGTACATTCCAAAAAATTGCCGGCAAGGAAGTCAAGCACTACAAATAGAAAT
TTGGTTGAGCTGGAAAGGGACATTACTATTTCTAGAGAGTACTAG
Promoter Sequence
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>MIP1 YOR330C
GTATGTAGGTATACAAGCTGCTGGTCGATCAATCAAAGAACTTTCTTGTCTTGGAAGGAC
CATACAATTCCAATCTGATGGCGGGCAATGCCTCTTCACTTAACAATTTCAATCTTTCCT
CCAAAGTGTTGTTAATTTCAATCTTGTCTGATGCATTGGAGACCACAACACCGCCGGAAA
CAAGGTCTTTGTTCAAGTAATCATTGGAGATAACAATCTCTTCCAATGGTGCGCGCTGGG
CCTTTTCCCCATACTCACGCATAATGTCGTCCTTCATCGACTCGATTAAATCGACGTCTC
TTTCAAGAGCCTTGACAATCGCCTTAGGTTCCAACAACTTCAAAAGTGCCTCCACGATCA
ATGATTGCAAAATGGGCTTGTACTCGTCCCGGTTGTTGGCAATTCCTGACAACTTTTCCT
TGGTTTCCTCGAATATCCCGTCTAGCGACTGTTCACGAGCAGAAAGAACCTTCAACCTCA
TTTTGTTTGCTATCGTTGACTTAGTAATCTGTTGCGAAAGCATGGCCTTCTTCAACTTGC
TCTTGAAGTTGCCGTCAATGTTGTTGGTTTCATTTCTTACGATGTTGGTCTTCTCGATTT
CGTACTCTTGGTCAGCCTTCAATTGGATTTCCTTCGCTTTTTCTTCAGCTTCCTTTCTGA
TGAAAGCTTGCATCTTGTTCAATTCATCGTTCACTTGGTTTGGTGTCAAAGCAGTAATAG
CGGAGGACATGCTGTATCGGATGGTGCGTGGCCTGTTCTGTGCCTCTTTTGTAAAACAGT
TACAAACAACTTTTCTTGCAACTGCTATTGTTCTTTGCTGATATATAGCGTGAGTTCTTA
TCGAAATGGCCGCTTTCGCCCCTCTCCGTGGCGGGTGACCTCGGGCGCACTTTTAGCCGA
TACTCAGTAAACAACAATAGGTATGGACTACGAAAGAACGGTTCTAAAGAAGAGGTCGAG
ATGGGGATTATATGTAGTTGTTGAGCAACGAGGGACAAGT
Chr coordinates
Chr XV from 943385-939621