Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
GPB1
Systematic Name
YOR371C
Alias
KRH2
Strain
S288c
Description
Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; promotes ubiquitin-dependent proteolysis of Ira2p; regulated by G-alpha protein Gpa2p; GPB1 has a paralog, GPB2, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>GPB1 YOR371C
ATGCCTCAAGCAAGCACATTCGGATCGCACAGTCTAGAAGCTCATCCCTTACACATTCAG
CCAGCTGTTCATATCAAACTCAGTAAAGAGGAAAGGTCTCACTACAGGGAGCAATACGAT
TCATTAAAGTATATTTCAAATTATGTTTCTGTTTTCGACCAAGCGTTAAGCGACAATATT
GACTCTAGGATTAGAAAAGAAAATGAAGCCTTACTGAAAAAATATTATGAATCAAGAAAA
CCTTTTACTTTTACCAGCTTTAGGCAAGGAAGTGTAATCAGTTCTTCTGATTCTTCTACA
GGCTTCACTGAGAGAACAAAGACCTACTGTTTTTTGAACGATTTCGTCAGTAATTGCGTA
AATGAGGTAGATCCATATACGCTGAAAATGACAGTAAGAAATAGAAACACTGCCTTGAAT
ATGGAGAACCTCGATGATGAACGTAAGAGCAAAGATGATATATACGATTTTGAAGATAAT
ACTGACGACGAGTGTAATGCCAAGTGCCATGGTGCTTTCCATTATTCGTCAGAAAGATTG
GAAATTCTTCGCTCACGTTCGACAATATCGTACTTTAAGTATTATAAAAAGCTTTTGACG
GTAGACCTAAGGGACAGTGATGTTTTAAAAAGGCATAATTTATGGATGCCAATGATCACT
AGAAGATTTAGATTTTTATTAGTATCAAGTTCGAAACCGGAAGATGTAAGGTTAACAACG
CCGATTCCAACATTCTCGGAATCAGATTTAGACATTTTCAAGAACAAGACATGTCCACTC
TTTATCAATGGTACAGACTGTGTTCCTAGAAGTTATGACACTTTTTCGGGTTCTTCTGTA
ATCGCTTCAATATTTTCAGAATATAAACTTCCATCCCTTTCATATCATTGTTCTGTCGAG
TTGAACGACCAATTATTTATTGTCGGTGGTTTGATGGCATGTCATAGATATGATGAGGAA
GCGCCTGATCTAAAGGATTTTTACGTGGATGGCATAAAGAATTTACCGCCACCACTAATA
CCAGAGCTAATTAATAACCCATCCATGATTCCTAATCCTCACTTGTACTGTTTTTCCTTG
ACTTCTTCCAGACTAACAAGACCTGATATTTCTGGTTACATTCCGCCCCCACTGGTGTGC
ACCCAGGGCTGTAAATTAACTGAAAGGCATATCTTTTTGTATGGCGGGTTTGAAATCAAG
TCGGAAACCCAAGTTGATGATAAGGGAAGATATTTTATAAGAAAAAGAGCTTTTTTGAAC
AATACTGGTTACATTCTAGATACAGTGACGTTCAATTTCTCAAAGATTGAATTAGTCGCT
CCTCCGTACCAGTTTGCAATTTACAATAATTTCTCGCCAAGATTTGGTCACATGCAGGCA
TCAATAAGTAATTCCAACAACAATGTATCCAATGAAAATACCACAACAAGTGCGAAAGGA
AGAAGGTCGATAAGCCCATATCGCCAAGGTAATGGGGATCACAAAATAGATGATTTGGTT
GGTTCACCAGGAAGTACGGACTATTTAGAGGATGATGCAATTCCACCTGTAACAAACCCA
AGGTCTACAGATAGTCTCTCTTCCAAACATTGTAGCACAGCAACACACATTTGCTCATCT
GTTAATACCATTCTGATCTTTGGAGGGTATAGTCAGACTGGTGACGACAAGTATGAAGCT
ATGAATGACATGTGGAAGATAAATATCCCTGTAGTTTCTCGTGGGAAACGTAATTATTAT
AAATTTGCAGATACTGTAACTGCTACTAAGATCCCTATTATTGATGATCCAGAATTATGG
CCGAGCAGAAGAGCCTTTTCAGCGTGCTGTGTACCAGATTATTTTACCAAGGATGTTGAA
CCCATAGAAACGAGATTACTGAGGAACTTGAAAAATGACTTCTCCATCGATTTGGAAATA
CGCCCAGGAAATAAGCCTTCTCAACCACTTTTTCCGAATATCCCACATTCAAGGAAGGAG
AAGAAGAGTGGTCGCGATAGTATGCATATTTCCAATTCTAATAATAGTACTAGTGAAGAC
ACTTCTTCAAAGTCTACCAGGAATACCACATCCAGTCCTCCCACAAGCCCTAAACATACA
CCACCATTGAATCCATCAAAAAAATGTGCATCAATCGGAAGAACTATTGCGTTCCACGGA
GGTTCAGATGGCTATGACGTTTGCAGCGATATGTGGTGGTTTGACTTCGATTCCGAAACC
TGGACTAAAATAGACCTTTATGCCAAAACACAAGAGGAATCTGATGGTTTGGTACCTATC
AACTTATGTATGGTAGGACACTCAATGACAACTGTAGGCCACAAGGTTGTGCTTATCGGG
GGTCTACGACAAGGTGATGTTGACCGAATATACCGGGACGAAACTCTTCCTGAAGAAGTA
ATATCGGGTGTTCCACTCGGAAGTGGCGTTATAAATGTCGTGGATTTAAATACACAATGC
CTTCAAGGTTGCAAGCTAATACGAAATGATGGAGATACTAAAGAATCTGTCATTATGGAT
CCTCATGTCGGCACACCCCACCAAGTATTGGCCGTCGCAGGTACTATAGAACTGGTCAAA
GGAACCATGACCTTAATAGGAGGTGTAGTAGCCGGTCGCGAAGACATTTCGAGCCTTTAC
TTGAGAGGAGCTGTCTTACAATTCATTCTACCAAGCATGAATCTAGCCAACTAA
Promoter Sequence
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>GPB1 YOR371C
TGAGCTACCCAAGATGGGGTCTTTTAGAAGTGATACGGGAATCAATCCAATTTCAAGTTC
AAACACAGTTTCTTTTAAGAGCAAATCAGGCAATAATAATTCAAAGGGTCGAATCAAAAA
AAATGGGAAGAAACCTTCCAAATTTCAAATTATTGTGGCAAATATTGATCAATTTAACCA
GGATACATCATCGTCATCTTTATCATCATCATTGAATGCAAGTTCGAGTGCAGGGAATTC
AAATTCAAACGTAACAAAGAAAAGAGCAAGTAAACTCAAAAGATCACAGTCTTTACTTTC
TGATTCCGGATCGAAATCACAAGCAAGGAAAAGCTGTAATTCTAAATCTAATGGAAATTT
ATTCAATTCACAGTAATATTAACCAAACTTGCATCTCACCTTTTTTTTTTAATCGAAATT
TCAAGCATTTTTCTCTCCTTCGCTTAGTCTTGTTTCATCCCATTCAACATTTTTTATTAC
ACAACATTTTGAAAATATCTTAAAAACAAAAAAGAACGATCACAAATTTATGGCACGAAG
AATACATACATCAATCGAGGACATTTTTTACATTTTATTTCATAATCATCATTTTTTCTT
TTCTTTACTACTATTCTGTGGTTTCATATTGTTCGTCAGGATGTTCATATATATTAAGGA
GTTTAAACTATATACATATGATTAGGTAAATAGGTAACTATTTTCAATCAATTTATTATA
AGTATCATTAATTGATGTTACTGCCAGATTTTACGATATTCCCTCTAATTTCCGGGTATC
CCATAAAAGCAATTCCCCGGCGTATAATTTCATTATTATGACATGGCTGTTAGTATGGTA
TGGTGCCCATCACATAAGTCACATATCGAGTCGAAATCGGCATTTTTAAAGGAAAGGAGA
AGAATCTTGCAAAAGCAGCACTTTCTTTAACTCAAAAATTGAGCCGACCTCCCTATATCG
GCTACTTTAAGGCTTTCCGTACCAATTCTTCTACATAAGA
Chr coordinates
Chr XV from 1034182-1031489