Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name NCR1
Systematic Name YPL006W
Strain S288c
Description Vacuolar membrane protein involved with Npc2p in sterol trafficking; transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; cells lacking Ncr1p exhibit high levels of long chain bases (LCB), similar to the accumulation of high amounts of lipids observed in patients with Neimann-Pick C, a disease caused by loss-of-function mutations in NPC1, the functional ortholog of Ncr1p
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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Promoter Sequence
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>NCR1 YPL006W
AGCTCGAAATCCAGTTTATTTTCAAATTCTAGCGGGAATTCTTTCACATGAAATAAATTC
TTACTGTTGCAATTAATGTCTTTAGCATATTTTGGCTGCCCAATGCTAATATCAGGAAAT
GTGGTCAAATATAGAGTACCATCCCGAGCCCATGTTAAATTGTTCTTCCAATCCTCAAAT
TCCTTTCTATCTACCAATAAGTCCTTTAGAAGCTTCATTATGAATTGAATTGGCTTTCCT
AACTCCTAACAAAGTTAGTCATGCTGCTTTTTTCATTATATATAATTCTGTCTAATCATT
GTTTAGATCTCATTATTGAGAAAAGTGCGTTGCGCGTAAGAAACAGAATACACTTAAGGT
GCGAAATGACGGAAGAAATACGCCATTTAAAGCCTTCCAATACGAAGCAAAACTTCAAAA
GCAAATGCTGGGAAGTTGGATTATCTTTGGGAAGGTCTATTTCCTTTTTTATTGAAATAA
ATCATTCAGCTAATTGCATACCGTGGCTAATGTCACAACAGATGTAAGCAACAATTTAAT
CTTACATAAATGTGTTGCAGTTGTGGTATTTCGTAATATATACGCAATGATTCTCTCCTA
TTATTGAACTGCTATGCAGGTATTCGCTACATTGTTTTTCTACAGGCAGTCGTCGACATA
AATAACTTGTATAATCATTTAAGCGCATCCCAGTAATTAACTATTACCGAACGATAGAGT
AGTCAAGATATTCTCTTCCCATCACTAACATCAAGAGCGCCACTTTTTGGCAATTAAACT
AGACTTCTGGATGGCGCTAGCCCATTACCTACAGTACTAAAGATTATTTGCGATATTCTG
ATAAAGAGCCTTGAACTTCTCGGGTGACCCCCTTAGCGTTTATATAGCGGGAGTGCCAAA
CGAGAGGAACATCAACAACCAGTATAACAACGTTCTTGTGTAGAAGATAACTAAATTCAT
CTCCAAAAAGAACAAGAGCAGAACTTCAATTAGTAAAACC
Chr coordinates Chr XVI from 544631-548143
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