Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
NCR1
Systematic Name
YPL006W
Strain
S288c
Description
Vacuolar membrane protein involved with Npc2p in sterol trafficking; transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; cells lacking Ncr1p exhibit high levels of long chain bases (LCB), similar to the accumulation of high amounts of lipids observed in patients with Neimann-Pick C, a disease caused by loss-of-function mutations in NPC1, the functional ortholog of Ncr1p
External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden
Promoter Sequence
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>NCR1 YPL006W
AGCTCGAAATCCAGTTTATTTTCAAATTCTAGCGGGAATTCTTTCACATGAAATAAATTC
TTACTGTTGCAATTAATGTCTTTAGCATATTTTGGCTGCCCAATGCTAATATCAGGAAAT
GTGGTCAAATATAGAGTACCATCCCGAGCCCATGTTAAATTGTTCTTCCAATCCTCAAAT
TCCTTTCTATCTACCAATAAGTCCTTTAGAAGCTTCATTATGAATTGAATTGGCTTTCCT
AACTCCTAACAAAGTTAGTCATGCTGCTTTTTTCATTATATATAATTCTGTCTAATCATT
GTTTAGATCTCATTATTGAGAAAAGTGCGTTGCGCGTAAGAAACAGAATACACTTAAGGT
GCGAAATGACGGAAGAAATACGCCATTTAAAGCCTTCCAATACGAAGCAAAACTTCAAAA
GCAAATGCTGGGAAGTTGGATTATCTTTGGGAAGGTCTATTTCCTTTTTTATTGAAATAA
ATCATTCAGCTAATTGCATACCGTGGCTAATGTCACAACAGATGTAAGCAACAATTTAAT
CTTACATAAATGTGTTGCAGTTGTGGTATTTCGTAATATATACGCAATGATTCTCTCCTA
TTATTGAACTGCTATGCAGGTATTCGCTACATTGTTTTTCTACAGGCAGTCGTCGACATA
AATAACTTGTATAATCATTTAAGCGCATCCCAGTAATTAACTATTACCGAACGATAGAGT
AGTCAAGATATTCTCTTCCCATCACTAACATCAAGAGCGCCACTTTTTGGCAATTAAACT
AGACTTCTGGATGGCGCTAGCCCATTACCTACAGTACTAAAGATTATTTGCGATATTCTG
ATAAAGAGCCTTGAACTTCTCGGGTGACCCCCTTAGCGTTTATATAGCGGGAGTGCCAAA
CGAGAGGAACATCAACAACCAGTATAACAACGTTCTTGTGTAGAAGATAACTAAATTCAT
CTCCAAAAAGAACAAGAGCAGAACTTCAATTAGTAAAACC
Chr coordinates
Chr XVI from 544631-548143