Yeastract
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YEASTRACT+ INESC-ID IST IBB
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Locus Information

Standard Name NCR1
Systematic Name YPL006W
Strain S288c
Description Vacuolar membrane protein involved with Npc2p in sterol trafficking; transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; cells lacking Ncr1p exhibit high levels of long chain bases (LCB), similar to the accumulation of high amounts of lipids observed in patients with Neimann-Pick C, a disease caused by loss-of-function mutations in NPC1, the functional ortholog of Ncr1p
External sources Open in SGD external link
Open in KEGG external link
Gene Sequence
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>NCR1 YPL006W
ATGAATGTGCTATGGATTATAGCACTAGTTGGCCAGCTGATGCGGCTCGTTCAGGGAACA
GCTACCTGTGCCATGTATGGGAACTGTGGGAAAAAGTCAGTATTTGGAAACGAATTACCT
TGCCCTGTGCCACGTAGTTTTGAACCTCCTGTTCTTTCAGATGAAACAAGCAAACTTTTG
GTTGAAGTTTGTGGTGAAGAGTGGAAAGAGGTCCGTTATGCCTGCTGTACTAAAGATCAA
GTGGTAGCACTGAGAGATAACCTACAAAAGGCTCAACCTTTAATTTCCTCATGCCCAGCA
TGCCTCAAGAATTTTAATAACCTGTTCTGTCACTTCACTTGCGCTGCTGACCAAGGAAGG
TTTGTCAATATTACCAAGGTAGAAAAGTCAAAAGAAGATAAAGATATTGTTGCGGAATTA
GACGTTTTCATGAATTCGTCTTGGGCATCTGAATTTTATGACTCATGTAAGAATATTAAA
TTTTCTGCTACCAACGGTTATGCGATGGACCTAATCGGAGGTGGTGCTAAAAATTACAGT
CAATTCTTGAAGTTTTTGGGGGATGCTAAACCTATGCTTGGTGGATCCCCCTTTCAGATT
AATTACAAGTATGATTTAGCAAATGAAGAAAAAGAATGGCAGGAATTTAATGATGAGGTT
TATGCTTGCGATGATGCTCAATATAAATGTGCGTGTTCTGATTGTCAAGAGTCTTGCCCC
CATTTAAAACCTTTAAAAGATGGCGTGTGTAAAGTTGGCCCTCTGCCATGTTTTTCCCTT
TCTGTTCTGATCTTTTACACAATCTGTGCACTTTTTGCATTTATGTGGTATTATCTCTGT
AAAAGAAAAAAAAACGGGGCAATGATTGTGGACGACGATATTGTTCCAGAATCAGGTTCC
TTAGATGAATCAGAGACGAATGTATTCGAAAGTTTCAATAATGAAACTAACTTTTTTAAT
GGTAAACTCGCTAACCTATTTACGAAAGTGGGACAATTTTCCGTTGAAAACCCCTACAAG
ATATTAATAACCACTGTTTTTAGTATCTTTGTATTCAGTTTCATCATATTTCAGTACGCT
ACTCTTGAAACAGATCCAATTAATTTGTGGGTGAGTAAAAATTCTGAAAAATTCAAAGAA
AAAGAGTACTTCGATGATAATTTTGGGCCATTTTACAGGACAGAGCAAATATTTGTTGTG
AATGAGACAGGCCCTGTGTTATCATATGAGACACTTCACTGGTGGTTTGACGTTGAAAAT
TTTATTACGGAAGAGCTACAATCGTCAGAAAATATTGGATACCAAGATCTCTGCTTCAGA
CCAACAGAAGATTCTACATGCGTAATAGAGTCTTTTACTCAGTATTTTCAGGGGGCCTTA
CCAAACAAGGATAGCTGGAAAAGGGAACTGCAGGAATGTGGGAAATTTCCTGTAAACTGT
CTACCTACTTTCCAGCAACCTCTAAAAACTAATCTTCTTTTCAGTGACGATGATATTCTC
AATGCGCATGCGTTTGTTGTAACACTTCTATTGACCAACCACACTCAATCAGCTAATCGC
TGGGAAGAAAGATTGGAAGAGTATTTATTGGATTTAAAGGTCCCCGAGGGCCTGAGGATC
AGTTTTAATACCGAAATATCCTTGGAAAAAGAGCTTAATAATAATAATGATATCTCGACC
GTTGCAATATCATACCTGATGATGTTTTTATATGCTACATGGGCCTTGAGGAGAAAGGAT
GGGAAAACTAGGTTGTTACTTGGAATATCTGGTTTACTCATAGTTTTGGCTTCTATTGTT
TGTGCAGCCGGATTTTTAACTCTTTTTGGTTTGAAGTCGACATTGATCATAGCAGAAGTA
ATACCGTTTCTAATTTTAGCAATAGGAATAGATAATATTTTCTTGATTACACATGAGTAT
GATAGAAATTGCGAGCAAAAACCGGAGTATTCAATTGATCAAAAAATAATAAGCGCTATC
GGGAGAATGTCTCCTTCCATTTTAATGTCATTGCTATGTCAAACCGGATGCTTCTTGATA
GCTGCATTTGTTACAATGCCAGCTGTCCATAATTTTGCTATATATTCCACAGTTTCTGTT
ATATTCAACGGAGTATTACAGCTAACAGCGTATGTGTCCATTTTGTCTCTCTACGAAAAG
AGATCCAATTATAAACAAATTACCGGAAATGAAGAAACTAAGGAATCATTTTTGAAAACG
TTTTATTTTAAGATGTTAACGCAAAAGAGGCTCATAATCATTATCTTCTCGGCTTGGTTT
TTCACATCTCTGGTTTTCTTACCAGAAATTCAATTTGGGCTAGATCAAACATTGGCTGTT
CCACAGGATTCCTACCTGGTTGACTATTTTAAGGATGTTTATAGCTTCCTAAACGTAGGA
CCACCGGTTTACATGGTCGTGAAGAATTTAGATTTGACTAAAAGACAAAACCAACAGAAA
ATATGTGGTAAATTTACAACTTGCGAAAGAGACTCATTAGCTAATGTACTGGAGCAAGAA
AGACACAGGTCAACAATTACGGAGCCATTGGCTAATTGGCTGGACGATTATTTCATGTTT
TTAAATCCTCAAAACGACCAGTGTTGTAGATTAAAGAAGGGAACAGATGAGGTTTGTCCT
CCCTCTTTTCCAAGTAGACGTTGTGAAACTTGTTTCCAGCAGGGTTCTTGGAATTACAAC
ATGTCAGGGTTTCCTGAGGGCAAGGACTTCATGGAATACCTAAGCATATGGATTAATGCG
CCTAGTGACCCCTGCCCTCTAGGTGGTCGTGCGCCATATTCGACTGCGTTAGTTTATAAT
GAAACGAGTGTGTCTGCGTCAGTTTTCAGAACAGCTCATCATCCTTTGAGATCCCAAAAG
GACTTTATCCAGGCGTATAGTGATGGAGTTAGGATATCAAGTTCTTTCCCCGAACTAGAT
ATGTTTGCATACTCGCCGTTTTACATTTTTTTTGTTCAATATCAAACTTTGGGACCATTG
ACGTTGAAGCTAATAGGGAGTGCCATTATCCTAATTTTTTTCATTTCATCTGTTTTCTTG
CAGAATATACGCAGCTCATTCTTACTGGCTTTGGTCGTTACCATGATTATCGTAGATATT
GGTGCTTTGATGGCCCTACTAGGTATCTCACTCAACGCTGTCAGTTTAGTCAATTTAATT
ATTTGTGTCGGTTTGGGTGTCGAGTTTTGTGTTCATATTGTTAGATCATTTACAGTGGTC
CCCAGTGAAACCAAGAAAGACGCAAACTCAAGAGTTCTCTATTCCTTGAATACCATAGGT
GAGTCCGTCATCAAAGGTATAACTCTAACCAAATTCATTGGAGTTTGTGTACTTGCATTC
GCCCAATCGAAAATATTTGATGTATTTTACTTTAGAATGTGGTTTACACTAATCATTGTA
GCAGCATTGCATGCTCTCCTATTTTTACCTGCTTTACTTTCATTGTTTGGTGGTGAAAGC
TATAGGGACGATTCCATCGAAGCAGAAGATTAG
Promoter Sequence
Download FASTA
>NCR1 YPL006W
AGCTCGAAATCCAGTTTATTTTCAAATTCTAGCGGGAATTCTTTCACATGAAATAAATTC
TTACTGTTGCAATTAATGTCTTTAGCATATTTTGGCTGCCCAATGCTAATATCAGGAAAT
GTGGTCAAATATAGAGTACCATCCCGAGCCCATGTTAAATTGTTCTTCCAATCCTCAAAT
TCCTTTCTATCTACCAATAAGTCCTTTAGAAGCTTCATTATGAATTGAATTGGCTTTCCT
AACTCCTAACAAAGTTAGTCATGCTGCTTTTTTCATTATATATAATTCTGTCTAATCATT
GTTTAGATCTCATTATTGAGAAAAGTGCGTTGCGCGTAAGAAACAGAATACACTTAAGGT
GCGAAATGACGGAAGAAATACGCCATTTAAAGCCTTCCAATACGAAGCAAAACTTCAAAA
GCAAATGCTGGGAAGTTGGATTATCTTTGGGAAGGTCTATTTCCTTTTTTATTGAAATAA
ATCATTCAGCTAATTGCATACCGTGGCTAATGTCACAACAGATGTAAGCAACAATTTAAT
CTTACATAAATGTGTTGCAGTTGTGGTATTTCGTAATATATACGCAATGATTCTCTCCTA
TTATTGAACTGCTATGCAGGTATTCGCTACATTGTTTTTCTACAGGCAGTCGTCGACATA
AATAACTTGTATAATCATTTAAGCGCATCCCAGTAATTAACTATTACCGAACGATAGAGT
AGTCAAGATATTCTCTTCCCATCACTAACATCAAGAGCGCCACTTTTTGGCAATTAAACT
AGACTTCTGGATGGCGCTAGCCCATTACCTACAGTACTAAAGATTATTTGCGATATTCTG
ATAAAGAGCCTTGAACTTCTCGGGTGACCCCCTTAGCGTTTATATAGCGGGAGTGCCAAA
CGAGAGGAACATCAACAACCAGTATAACAACGTTCTTGTGTAGAAGATAACTAAATTCAT
CTCCAAAAAGAACAAGAGCAGAACTTCAATTAGTAAAACC
Chr coordinates Chr XVI from 544631-548143
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