Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
MUK1
Systematic Name
YPL070W
Strain
S288c
Description
Guanine nucleotide exchange factor (GEF); involved in vesicle-mediated vacuolar transport, including Golgi-endosome trafficking and sorting through the multivesicular body (MVB); specifically stimulates the intrinsic guanine nucleotide exchange activity of Rab family members (Vps21p/Ypt52p/Ypt53p); partially redundant with GEF VPS9; required for localization of the CORVET complex to endosomes; contains a VPS9 domain
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>MUK1 YPL070W
ATGGCTAGACAATTATTCACTCCTCCGATAACCAATCCAAGGTTTGACCCTAATCAATCC
ATCAGGGAATCATACAAGAACACAACTGGCGGCATGCAATTTCAACAAAATCTACATGAG
GATCAAAATGACAATGAGAGAAGTAGCTGTGATGGTGATGAAAACTCTACAACAGGAGAA
AGGCTAGAAAACAATAAGTCTCCTATATTGACAAAACAAGAAATTGACGAAGCGTTGAAC
ACTGTCACCAATTTACCTCCAGAATTATCAAAATTAATTGACATTTTTATTGATGACCTA
AAGCAGCCAAAGTACGTACGGCCACTATCAGTACTGCAATTGTCTAGTCTTTTCCAAAGC
TTTTACATAAAATTTGATAAAGCATCATTCCAGCACGTCAGTTCAGCGAATAATAATGGC
TATTATTTTTCTGGCGGGGGCTCTAGTTCATTCTTGGCTGCCAAAGAAACGTTAAGTAGT
GGTCTTAGCGGAATTTTTGGCAGAAGTAGGAGTAGTAGTGGAAATTCACTTATGAGGCCA
AGAAGATCTTCATCGCTTTTCAGTAATGAGTCAATATCAAATTCAACTAATGCCACACAA
ATGTTGTCACCTGAAGAGATAAAAAAGCAATTGAAAATCAACGAATTAAACAACATGAAA
ATCGAAAAATATATGGAACTTTGTGAAAGAGATGTTTTTAAGAAAATTCTTATAGTAGGC
ACATCCGTATCTTCACCGAATAAAATGAAAACCTTCAAACCACACCAATTACAAACTTTC
AAGGTTGGAAATCTATTTAGAAACAGTGTTGAATTCACAGAATACAATAAGTTGTTGAAT
GAAAAAATCCTCTGTTTGTCCAAACTCTCAACAATGAATAAAATCAATTTGATAAAGTTT
CTGAGTCTTAATAATGGCATTGATCCGGAACCAAAGTTTGAAGAGATCAAAGATATTTTA
TATGAGTTTACTTATCATTCGATTTCACCATGTGAAAAGATAAAGGCCCTACTGAAACTA
CATGAAATCATGACATATTCCCAAGAAATGTCTAATGATGATTATCTTTCGTTGCTAATC
TACTACATTATTACGATTGTTCCACGGGATATTTTCTTGAATGCCGAATTCATCAGGCTG
TTCAGATATAAGAAAAAGCTGGTCGAAACAGAATCCTTTGCATTAACCAATCTAGAAGCT
GCATTAGTTTTTGTTGAAGGCTTAACCAAAAATGATTTTTCAAATGAGCTACAAGATAAA
TTGACTGTAAATGAAAGTAAAATTTTAGAAAATTCAATCAGCAGTAGAGTCTCATTGCCA
TCAAAAACTGCTATAATGCATAAAAACAACGGTAATAACGGCAGTAACCTAGGTGACATC
GTGACTCCTACTATCCAAAGGCCAGATGTTACAAGATCGAATTCGTATGATGGCTTCAGG
ACCGTTTTTGATTCATCATTAAAAAATATCATCGGAAAAATTAGGTCATATACTCCACCA
CATCCTAACAATACTAGCAATAATAACCTTCACAGTAGCAACAACTTAAACATACCACGA
AGTTCGTCTCAATTATCCATGGAATTGAGCAATAGAGATACAACAGAGATGTCTAGGGAT
GGCTCACGATCAACTTCATCATCTTCACGATCTTCAGCATCTTTAGAGCACGGAAATCGC
GAATTTACCGGCGATTTGACAGTAACCGCTAGCATTAACGGTGCTGATAAAAAGGAGTTT
CAGAAATCGTGGAAAAAATATAAAGGCTATAAATTTGAAGATTTGACTATTTGCGAACTA
AGAGATCTTTTTGAGATATATCAAAAGATGATGCAATGA
Promoter Sequence
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>MUK1 YPL070W
TTCAACTGTCTTGAATGAACAGAAATATGCTTATATGCTATACTACGAACGTGTAAATAA
ATAACCGCCCTGTACATAGGTATATTATAATAATAGTAAGTTACGCATCCATATCCACAT
CAGTATCCACTGCCATCATTTCAACATCGGTATCAGCCTCTCCATCATAAGTGTATTTCG
AAGTCATTTGATTATGGAACCACTTCCACCAGCTTAGATAAGCAATTTCCTTATAATCTA
CCCATTTTATTATTTGTAGCCTTTTTTCTCTCAAACGTTCCCATATTTTGTCATAAAACA
AGTCATTGTCGCCGCGTTTACTTGTGGAACACTTGATGATCTCTTTCAGGACCTTATCAT
CAATAGCGTCTGTGAATACTATATTGTTATGAATAAGATTGTTATCATCTGCATGTCCGT
TCTTGGGCCCTTTATCATTTAAGGATAAATTCTCTAAATCTATAATTAGTCTTTTTCTTT
TATAATTATCAATTCCTATTGGGTCTGGAGAATGATTTCTTTTCCTAATGTGGTTGGGAT
TGCCATTACTTCTTGCAAACCGGGAACTCATGGAATGAAAAAGTCATTTAAACGTGCCAC
TAGTTTTACTATCTGCTAATCGTTCTAGACGTGTAATATAAATCATATCCGAGCGCCGTT
GTTGAATAATTTAATGCCTTCGTATTACATACATTTTGAAATTTGCTTTCGTAAAAGAGC
GGTTCCCGGATAAAAAAGTGTGCAAATAACCGAGCCTTATTTGATTTCCAGTAAAGACCC
AACCAAACGCATCATTGAAGCAAAAATAGATTAAAACTTACTGTTGTTCGTCTATTGAAT
TTTGTTCGGATTGGTGTGGTGTTTAATATCTTGGGCAGAAAGAGAATTGGCTTTATAGAC
ACTCATAAAATCATCATTCCCCTTAGAGCAAAAGGTATTTTTAGAAGCCAAGAAGAAGAG
CAGATAAAAAAGAAGTACGCCCTCTAACAATAAAAGTCAA
Chr coordinates
Chr XVI from 420948-422786