Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
PNG1 Systematic Name
YPL096W Strain
S288c Description
Conserved peptide N-glycanase; deglycosylating enzyme that cleaves N-glycans that are attached to misfolded ERAD substrate glycoproteins prior to proteasome-dependent degradation; localizes to the cytoplasm and nucleus; activity is enhanced by interaction with Rad23p; human ortholog NGLY1 is associated with a syndrome characterized by developmental delays, epilepsy, absence of tears and liver disease External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden Promoter Sequence
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>PNG1 YPL096W
CAGTTCTTTTATAATACTTTGGATGCTGATGTACCCAAGTTCTTGAAGATCTTTACGTTT
TTAAACTCAAGTGAAATCAAAAAAATTGTGGAAACGCATATCAAATCACCCAGTCTACGT
TATGGCCAAACTTTATTGGCTAAAGAAGTCACAGATATGTTATATGGAGTTGGCTCCGGA
TCGGATTCAGAAGCGCTTTCTAATATTATTTTTGGACGTTATGACGGAACTTTATCTGCT
GCGAAGTTAGTTGATCTATGTAAAAAAGCCAGAATTTTGCAGTATGCTGATAGAGAGATT
GACTTAATAAAGTTAATTTGTAAACTAGTAAATTGTTCAGTATCAGAAGCCAGAAGAAAA
CTTTCCCAGGGAAGCGTGTATCTGCATCATTCAAAATCTAAAGTAAACGAAAATATTTCT
AACTTGGCTCCTTTCCTGATAGATGATCGAGTACTGATCTTGAGGATAGGAAAGCAGAAG
TGTTTTATAATAGAAATGCGTTAAAAAAAAGGGAGGTATATAAAGTACATGTATAAAATA
GGCATGCGTGAGGTGATATTATATCATTTTATGCACTGACTTGTAAATAAGATTATAAAC
GATTATTCATCTTTACTACTTGCGAACATTTCACTGTCACACCAGGCTATGAGGGCCCAC
AGCCAGAGAGTCGCAGGGCATAGCAGTAATACACACCAGTAGTGCAGGAAAGAGTCATTG
TTGCGTAACCAGTAAAATGTAGCAAGACTAATTAGGAGTACCGAGTAAGTAAACCCTAAA
ACCAAAAAGCCTTGGTCACGTGGTCTCATGCGCTTATAAATTCTCAATCATGTAATTGAA
ACAGTCCTGTTGCCTAGTTTCAACTGTTCTATGCTTCTTGATGTTTTCGAAACTTTGCGT
AGTGTAATCTTCCTTGTATTGTAGCGAAGAAAAAAGGATGCGTTGGGAACAGATATAGAA
GACGTAAAACAACCTGAAGAAGGTAACAGGTGGAGTAGCA
Chr coordinates
Chr XVI from 366927-368018
