Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
TBF1
Systematic Name
YPL128C
Alias
LPI16
Strain
S288c
Description
Telobox-containing general regulatory factor; binds TTAGGG repeats within subtelomeric anti-silencing regions (STARs), blocking silent chromatin propagation; binds majority of snoRNA gene promoters, required for full snoRNA expression; caps DSB flanked by long T2AG3 repeats and blocks checkpoint activation
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>TBF1 YPL128C
ATGGATTCGCAAGTGCCCAATAATAACGAAAGCTTAAACCGCTTCAATGACATCATCCAA
AGCCTGCCTGCAAGAACTAGGTTGACCATATGCTCATTATGTCTGCTGGACAATATCTCC
ACTCAACTACTGAGGTTTCTTATCCTTAATGCCAACTCTCCCAATATTATAGCGGTTTTG
ACGGACCAGACGGCTTTCCTAAGCTCAGGCGAAACAGAAATTTTTCAAACGTTAGTCAAG
CTCTTTAAGCAGATCAGAATGATTTACCACACCAGATCTCCGTTACTGTCTGTTCACGAC
GTGGCGCCTGGTTTATGGTTTCCCAACTCCCCTCCCCCCCTTATATTGAGAGGCCACGAA
GCGTTTATTATTACTGCCATAAGAAAGGCGAATCTGCTAACATTTCTATTGACGTCGCTG
AACTGCCTTAATTACGGGTTTGAGCTGCTACAGTCGATATTTCTCGATATTTTCTGTCCA
AATACAAACACTGTCGGTAACAACTCCCTGGAACAAAGCGGAAAGTTTTTGAAATCGCAG
GCTATCCTATATCTTGATCTGAAAACACAGGCTTACATTGCCGGCTTGAAAGAGTTTCAG
GACGAGACGAACGAAATTTCTTTAGAAAAGAAACAAGAGCTACTAGACTTAATCTTCCCA
TCCAATCTGGCTGATATTCTCGTGCAGAGAAGAACCGGCGATTCTGGAGACATTACACTT
TTGACTCCATCGGAGAAGGACTTCGTCGAAAGGTGCGATCGTCGGAGAGAAAATTTAAAG
ATCGTCCAAGATTTTAACTCTCTGACCCAGAGCTACGAATGGGCTCAATTTATCAGAGAG
TTGCTGGATTATTGTAATAAAAATATGGGTCTCATCATATGGGGCAGAAAGGGTCGCGGA
AAATCACCATTATATGACTTTGATGTCAACGAGTTTGATCCTCAAGTACTCTTTTCTACA
GGGACCAGGACCGTAGAATTCATGGACGACCAAAATCAGCCAAGCAGTGCGTCTGCTTTT
TTGTCAACTGCTCGTCCGAATCATTACAGCACACATACACCTACCACAGATGTGTCTTCC
AAAAACCCCGCTATCACACAATCCATTGTGGATGCCGCTGTTGCGGCCTCGATGAGCAAC
AGCAGCTCTGGTCCTCATTCCTCTCATAACAACAGCAGTAACAGCAACAATAATGGTAGT
ATCGGATTAAGAAAACCAAAGGCGAAAAGAACTTGGTCCAAAGAGGAAGAAGAAGCATTA
GTGGAAGGCCTGAAAGAGGTTGGCCCATCGTGGTCTAAGATTCTAGATTTATATGGTCCC
GGTGGTAAAATCACGGAAAATTTGAAGAACAGGACGCAGGTACAACTGAAAGATAAAGCC
CGTAATTGGAAATTACAATACTTGAAGAGTGGCAAACCATTGCCTGACTATTTGATAAAA
GTGACCGGTAACTTGGAGAAAATCTACAAGGCAAAGAAAAAATTCTCTCAATCTCCAAAT
TCGTCAACTATTATGGAACAAAATTTATCTCAGCATCCTTCATCAGCTGCATCTGCTACT
GAAGACACTCAAACTCATCAAGAGGATTCACATGGGCAAAATAGTGATAATATGCCATCT
AACGGACTTTTTGGCAATAGTACATCGGACAATACAGGTTTTGATCCTCATTTAGAAGAT
GGGATGTAG
Promoter Sequence
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>TBF1 YPL128C
GGTCAGTCCAAAACCCAAGCAAGCCGCCACTTCTGTGAGTGCAACCGCATCAAAAGCGAA
AGCCGCATCCACGAAGCTAGCGCCAAAGAAAGTAGTGAAAAAAAAATCGCCTACTGTTAC
CGCCAAGAAGGCCTCTTCGCCTTCTTCATTGACCTACAAGGAAATGATCCTTAAAAGCAT
GCCTCAACTTAATGACGGTAAGGGCTCCAGCCGTATCGTTTTAAAGAAGTATGTCAAGGA
CACTTTCTCCTCCAAGTTGAAAACAAGCTCAAATTTTGACTATCTGTTCAATAGCGCTAT
CAAGAAATGTGTTGAAAACGGCGAGTTAGTGCAACCAAAGGGCCCCTCCGGCATTATTAA
ACTAAACAAGAAGAAGGTCAAACTCTCCACGTAAAAAGTGAATATCCAAACGAGAATGTC
AATGGTGATAGCAATACTATCAAACCTATTTTCTTTCTTCATTTTTGTGTCCCATCACTA
TTAGTATTTTGTATTATTTCTAAATTTTTTTCTCTCTAATTTTCAATCTTATTCAAGTGT
TTGTTGGCGGTACTGTAAATTTTCATTTTTTAATCTCTCCCTTCTCTATTTGTTACTTAT
TCGGTAAATATCTCCTTTATGATTTTATTCAAATTCCATTCTTAACTAACTAACTATACT
GTTTATAAATTTCTCTTCTCTTATATATGCAAGGTACAGTGTGTAAAATTAATTATTGTA
TTTGAAGAAAAGGCTTTAAAATCTGAACATTTGAAGCCCTAATATTCTGCACCGTGCCCT
ATTAATTTTCGCCCCTTTCCGTAGAAGCCCGGCGAGACCTCATTCCGACTAATTTTCCTC
AATGCTTTGCCCTTCCTTGTAAACATTATAATAAACAATCATCTCAATATTGGCGTTTTG
CTCCTATATCCTTGCCAACATTTAAGATTGTGGCTGTCCCATCTGCGACAGAAATCATTT
TACATTAGTTTTTCTTTACTCACTTCTTTCCCCATTTGTC
Chr coordinates
Chr XVI from 308221-306533