Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
ISU1 Systematic Name
YPL135W Alias
NUA1 Strain
S288c Description
Conserved protein of the mitochondrial matrix; performs a scaffolding function during assembly of iron-sulfur clusters, interacts physically and functionally with yeast frataxin (Yfh1p); ISU1 has a paralog, ISU2, that arose from the whole genome duplication; isu1 isu2 double mutant is inviable; human homolog ISCU implicated in mitochondrial myopathy, can complement isu1 isu2 double mutant External sources
Open in SGD
Open in KEGG
Gene Sequence
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>ISU1 YPL135W
ATGCTTCCTGTTATAACGAGATTTGCAAGGCCTGCTCTGATGGCCATCAGACCTGTGAAT
GCCATGGGGGTTTTGAGAGCGTCCAGCATAACGAAAAGGCTTTATCATCCCAAGGTCATA
GAGCATTATACACATCCAAGAAACGTCGGCTCATTAGATAAAAAATTGCCCAACGTCGGC
ACTGGTCTAGTGGGTGCGCCAGCGTGCGGTGATGTGATGAGGTTGCAGATCAAAGTCAAC
GACTCTACTGGCGTTATTGAAGATGTCAAATTCAAAACTTTTGGATGTGGCTCCGCCATT
GCCTCCTCTTCATATATGACTGAATTGGTACAGGGGATGACCTTGGACGATGCGGCAAAA
ATTAAGAACACTGAAATTGCTAAGGAGTTGAGCTTGCCCCCAGTCAAGTTGCATTGCTCT
ATGTTAGCGGAAGATGCGATCAAGGCAGCTATTAAGGACTACAAATCTAAGAGAAACACT
CCAACCATGTTATCGTAA Promoter Sequence
Download FASTA
>ISU1 YPL135W
GTAGAAGGCCTCGATGGCTTCGTATTTGTCTTCCGTCTACTCTTACCTTTATACAACCAA
TCTACGGGCACATCGAACTCGGTGTTAGTTATCATAACCTAGATGCTATCTCCACTCCCT
ATGCTTGCTTTGGTGGACTATTGTTTCCGTTATTCGCAATTTCTATAGGACTACTATAGA
TTATATAAACTGAATTTTAGCTTTATGCTGTGGTGTTATTTCCCAAAACACGCTCTTCTT
TCTTACGCTTTCCGTTAGCTTATTTGCTCACGGTATCAAGATTACTTTTTTTTTTTTTTC
TTCTTTTCTTTTTCTTGCACTACCCTCTTCTTCTTGTTCTTCCTTGCGTTTTTACCCCTC
TTCCCTTTATTTTGCAGCAAAAAGAAAGATGGAAAGGCAAAAGTGAAGGCATGATGATGA
CAAACTTGAAAAGAAAGAGAACAGCGAAAAGAGATGAATAATCCATGGCAATGACTGCAC
GCTCATGGGTATCAATTGGCTAGGTCTAATATTGTTATTGTTTGGAGTATGGCGTAGAGA
AGTGGTTCCTTAACCTTAATTAATGCCCGTGCCATGATGATTGCATCACTGAGACGTAAT
GTGGAAACACCACTTCTCGGTCCGCGGACATCAACCGAAGGAAAAATGACAAGCTATTTC
CGTGTATATCCGCGCCAATCCCTTCGGGGCCGAAGTTCGGAGGCTTTATCTCCGCTTAGC
CAAGGCCGTCAAAGGCGATAAGGTGCGTTGCACCCCAATTAGCCATGGAGAAGGAAAAAA
AAAGCATGTATGATCATGATGATGCAAAAATTGAGAGGAAAAATGACTCAGGCTATTTAT
ATAAGTAAATGAAAGGGTTTCGTTGTAGCCTTTTCTGCTCTCTTCCTTCGCTCTTCCGCA
TATATATTTGTGTTCAGAGATTATTCTTAAATCCATAAGAACATCCCTTCATATAACAAT
TGAATAAGGAAAACACAACACATAACACATATTTAACCTG
Chr coordinates
Chr XVI from 297553-298050
