Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
ATG5 Systematic Name
YPL149W Alias
APG5 Strain
S288c Description
Conserved protein involved in autophagy and the Cvt pathway; undergoes conjugation with Atg12p to form a complex involved in Atg8p lipidation; Atg5p-Atg12p conjugate enhances E2 activity of Atg3 by rearranging its catalytic site, also forms a complex with Atg16p; the Atg5-Atg12/Atg16 complex binds to membranes and is essential for autophagosome formation; also involved in methionine restriction extension of chronological lifespan in an autophagy-dependent manner External sources
Open in SGD
Open in KEGG
Gene Sequence
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>ATG5 YPL149W
ATGAATGACATTAAACAATTACTTTGGAATGGTGAGCTTAATGTGCTGGTATCGATCGAT
CCTTCATTTTTGATGAAAGGAAGTCCAAGAGAAATTGCGGTGCTACGAATAAGGGTACCA
AGGGAAACATATTTAGTCAATTATATGCCCCTCATTTGGAACAAGATTAAAAGCTTTCTT
TCTTTTGACCCATTGACCGACAGTGAGAAGTATTTCTGGTTTGAGCATAATAAGACGCCT
ATTCCGTGGAATTACCCAGTAGGTGTTTTGTTTGACTGCCTAGCCGGAAAAAGCGCTACT
TTTACCACCTCTTTTGAGAACCAGGTAAAGGATGTTCTCACTTTTTTGAGAATTCACTTG
GTTATGGGCGATTCGTTGCCACCAACTATCATTCCCATCGCATCTAGCAAAACGCAAGCG
GAAAAGTTTTGGTTTCACCAATGGAAACAAGTTTGCTTCATACTGAATGGTTCCTCAAAA
GCTATTATGTCTTTATCGGTCAACGAAGCTCGAAAATTTTGGGGCAGTGTTATTACGAGA
AATTTCCAAGATTTCATTGAAATATCTAACAAGATAAGTTCATCAAGACCGCGACATATA
CCGCTCATCATTCAAACCTCAAGGACATCAGGAACTTTTCGAATATCACAACCAACTATC
AGTATGACTGGAGTCAATCCTACGTTGAAGGATATTGAAGGCGATATTCTGGACGTAAAG
GAAGGAATCAATGGTAATGATGTCATGGTTATTTGTCAAGGAATTGAAATTCCTTGGCAT
ATGCTCCTGTATGATTTGTATTCTAAATTGCGAAGTTTTGATGGCTTTTTGTACATAACT
CTTGTTCCTATAAAAGGCGGCGATAAAGCTTCCTCTGAGCTCTAA Promoter Sequence
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>ATG5 YPL149W
CAAGAACAGATTCCTTTTACGATATCACTACAGCTACACCAGTTGTGACCACTGATAATA
GGCGCAATAAAAACAATAATCTGAAAGAGTCTGTTTTGCCCAGATTTGGGACTCAAAGGC
CATGGACTGGCAAAAGGACGTATACCACGTCCCGCCATGGCAAGAATGCTAGGCGTTCGT
CTAAAAGAGGTCTGTTCAAAATAACTTCTTCAAATACAGACTCTATTATTCAAGAAGTAA
GCTCATCAGAAGAAGAAGATCATAATGTTATCTATAGCAAGGGAAAGGGTCTTCCAACAC
CAGTTTTGCAAACTAAAGGATTAATAGAAAATGGGTTGAACGAACGCGATGAAGAAGGAG
ATGACGAGTATGCAATTCACACTGACGGAGAATTTTCTATCAAACCGCAGTTTTCCGATG
ACGTTATCGACAAACAGAATCATTTGCCCAGCGTGAAGGCTGTGGCAACTAAACGTTCGT
TGAGCGAAGGAAGTAATTGGTCTAGTAGCTATTTGGATTCGGACAATAATCGGCGAAGGG
TATCTTCATTGCTAGTAGAGGATGGGGGGAATCCTACAGCGTAGGTACCGGATAACAGAG
TAACTGGTAAAAACGGCAAAAAATACTGTAAGGAAGTTGTCTATATATGTACATATGGAT
ATTGCGGTATAATAAAAAAGCTTTAAAATTATAAAGAAACCCGACTTTTATCACATATAA
TTATATTATAAAAAAATAATGGCATCTGTATGAACTCGCGATTAAGCTCACTTTTTTCTA
ATGATCGAAGTTTTGTCCGGTTATCCAACTGTGGCAAGAACATCGCGAGGCGGAGCTAAA
CACAGAATTTTTGTAGCGCGATGAGAAACATAACGCCTCTTTAGATAAATTATCATCACC
TTTTTTACACTAAATAATGAAGTAGCATGCTCAGAAGTGCGAATGAATTTTTGTTCTTTT
GGTTCTAGAAGAACGGAGATAGGAAACCTATGATGTAAGT
Chr coordinates
Chr XVI from 271310-272194
