Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
TYW1
Systematic Name
YPL207W
Strain
S288c
Description
Iron-sulfer protein required for synthesis of Wybutosine modified tRNA; Wybutosine is a modified guanosine found at the 3'-position adjacent to the anticodon of phenylalanine tRNA which supports reading frame maintenance by stabilizing codon-anticodon interactions; induction by Yap5p in response to iron provides protection from high iron toxicity; overexpression results in increased cellular iron
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>TYW1 YPL207W
ATGGATGGTTTTCGTGTAGCTGGTGCGTTAGTAGTTGGTGCGTTAACCGCTGCATATTTA
TATTTTGGCGGAAGGTTTTCGATAGCGCTGGTCATTATAGTAGGTTATGGTATTTATTGC
AATGAAGCCAGCGGTGGTAGTCAAGATAGTCAAGAGAAGCTCGATTTGAACAAACAACAG
AAAAAGCCATGTTGCAGTGATAAGAAGATTGCGGATGGAGGAAAAAAAACTGGCGGATGT
TGTTCTGATAAGAAGAACGGTGGTGGTAAAGGTGGAGGATGCTGTTCCTCAAAAGGTGGA
AAGAAAGGGGGGTGTTGTTCATCTAAAGGTGGAAAGAAAGGAGGATGTTGTTCCTCTAAA
AAGAATATTGGTGACAATGAAAATACTGCCACTGAAGTTGAGAAAGCCGTAAATTACCCT
GTTACTGTGGATTTTACAGAAGTTTTTAGGAAGCCCACTAAGAAAAGGTCGAGTACCCCC
AAGGTTTTTTCGAAAAATAGCTCGTCTAACTCTAGAGTAGGTAAAAAATTAAGTGTTTCA
AAGAAGATAGGTCCAGATGGATTGATCAAGAGCGCGTTGACTATTTCGAATGAAACGCTT
TTGAGTTCACAGATCTATGTGTTATATAGTTCCCTGCAAGGTGCAGCTTCGAAAGCTGCA
AAGAGCGTTTACGACAAACTAAAGGAATTGGATGAATTGACTAATGAGCCAAAACTTTTG
AACCTTGACGATCTATCCGATTTCGATGACTATTTTATAAATGTTCCCGTTGAAAATGCA
TTGTATGTGCTTGTTTTACCGTCTTATGATATCGATTGCCCTCTAGATTATTTCTTACAA
ACTCTTGAAGAGAATGCGAATGATTTTAGAGTAGATAGTTTCCCATTACGAAAATTGGTT
GGCTACACAGTTTTGGGGCTTGGTGATTCAGAATCATGGCCTGAAAAGTTTTGTTATCAA
GCCAAAAGGGCCGATCACTGGATTTCTCGTTTAGGTGGCAGGAGAATTTTCCCCTTAGGC
AAAGTTTGTATGAAAACAGGAGGTAGTGCCAAAATCGATGAGTGGACATCATTGTTAGCA
GAGACTTTGAAAGATGATGAACCAATTATTTATGAGTATGATGAAAACGCAGACTCTGAG
GAAGATGAAGAAGAAGGTAATGGTAGTGATGAATTAGGCGATGTAGAAGATATTGGTGGT
AAGGGTAGTAATGGAAAGTTTTCAGGCGCAGATGAAATCAAACAAATGGTGGCGAAAGAC
AGTCCAACGTACAAGAACTTGACAAAGCAAGGTTACAAAGTTATTGGTTCCCATTCAGGC
GTTAAGATCTGCCGATGGACTAAGAATGAACTACGTGGTAAAGGGTCTTGTTATAAAAAA
TCGCTCTTCAATATCGCGTCCAGTAGATGCATGGAATTGACTCCTTCTTTGGCATGTTCA
TCCAAATGCGTTTTCTGTTGGAGGCATGGTACAAATCCCGTGTCAAAAAACTGGAGATGG
GAAGTAGATGAACCAGAATACATTCTAGAAAATGCTCTGAAGGGACACTATTCCATGATC
AAACAGATGAGAGGTGTGCCCGGTGTTATTGCAGAAAGATTTGCGAAAGCGTTTGAAGTT
CGTCATTGTGCCTTGTCTCTTGTCGGCGAGCCTATTCTTTATCCTCATATCAATAAATTT
ATCCAATTATTACACCAAAAGGGCATAACTAGTTTCCTTGTGTGCAATGCCCAACATCCA
GAGGCCTTGAGAAATATTGTTAAAGTAACACAATTATATGTTTCTATTGACGCACCCACC
AAGACAGAGCTGAAAAAAGTGGATAGACCTTTGTACAAAGATTTCTGGGAGAGAATGGTA
GAATGCTTAGAGATTTTGAAAACTGTACAAAACCATCAAAGGACAGTTTTCAGGTTAACT
TTAGTGAAAGGTTTCAATATGGGTGATGTCAGTGCATATGCAGATCTGGTCCAACGTGGT
TTACCAGGTTTCATTGAAGTTAAAGGCGCCACGTTTAGTGGCTCATCTGATGGGAATGGT
AATCCTTTGACAATGCAGAATATTCCATTTTACGAGGAATGTGTAAAATTTGTGAAGGCG
TTTACCACGGAATTACAAAGACGTGGATTACATTACGACTTGGCTGCCGAACATGCGCAT
TCCAACTGTTTATTAATTGCAGACACGAAATTCAAAATTAATGGAGAATGGCATACACAT
ATCGATTTTGATAAATTTTTCGTATTGCTAAACTCGGGCAAAGACTTCACGTACATGGAC
TATTTAGAAAAGACACCCGAATGGGCATTGTTTGGCAATGGTGGGTTTGCACCAGGGAAT
ACAAGAGTGTACAGAAAAGATAAGAAAAAGCAGAATAAGGAAAATCAAGAAACTACAACG
AGAGAGACGCCTCTCCCTCCTATTCCTGCTTAA
Promoter Sequence
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>TYW1 YPL207W
CTTCATTAACATACAAAATGAACAATGTTTAGAACCATTACTGGATCTTTTTACCTACCT
TTCTAAGGCCGAAGAGGAGGATCTACACGATTTGAGAGCCCGTTTGCAGGGTATACAAAT
GCTACGAAATGCATTGCAGAGCAAACTCAACAGCATTACTGGACCACCTGCAACTGATGA
CTCTTATGCAATTGATCCTTACAGAGTCTATTGTGCTGACGTTTATACTAAAGGTCAAAA
ACAAATTTTAAAAGAGGCTTTAACGAGGTTGAAAAAACTAGAAAAAACAATGCTGTCAGA
GAACAAGCACCAATTGCTAACCATGAGCAAAATTCTTAAGAATGACCCTGCTTTTGCAGA
AACTGAATTACCTTCGCTGTTCAGCAACGAAGATGGTGAAGAGGTCATCTTTGAATCTAC
TTATGATTTATTGATACTTTGGATTCTACTGAAAACGAAAAAGAATTCTTACCCCACCAA
ATATGAATGGGTTGGACAGCAGTATACTAATTTCAAGCAAACTGCATATATTTCAGATGA
TGCCAAGGCTTTCCATACTGCATACTTCGAGAAGCAAGACGATGTGGATTTGGCCGAAGT
AGATCATGCGATTCAGTTTGTAGTAGACAATTCCTTTACCAGAACTTCATCTACAACCGA
AGAGACTATTTTAGTACGTAAGTAGCTTTTCCTTATAGAATGTTAGAGTAGAGTACGTAA
TTACATCTGCACTTATTTAATAAATGCACTTACTAACAAACTGGGTTCTCATTGGTCAGA
AGTGTCCCGGGTATCCGAATATGGCTTCGATGAAATTTTTCGCCATGGAGCTGCGATGCC
CGATATTTGTGTATAAAACATGGAAATGAGCTTATATAGTGACTACTCTGCATTTTCGTT
ATTTCTAGAGCAGAGCTTAAGTTACCCATAGTTATTTCTATAGCTTGCCCTATCATCCAT
TTGATCAACAATAGGGAATAACTGTAACAGTAAGTAAATT
Chr coordinates
Chr XVI from 159909-162341