Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Metabolism
Standard Name
PUS1
Systematic Name
YPL212C
Strain
S288c
Description
tRNA:pseudouridine synthase; introduces pseudouridines at positions 26-28, 34-36, 65, and 67 of tRNA; also acts on U2 snRNA; also pseudouridylates some mRNAs, and pseudouridylation level varies with growth phase; nuclear protein that appears to be involved in tRNA export; PUS1 has a paralog, PUS2, that arose from the whole genome duplication
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>PUS1 YPL212C
ATGTCTGAAGAGAATTTGAGGCCTGCCTATGACGATCAAGTTAATGAGGATGTCTACAAG
AGAGGCGCTCAGAGCAAATTGACCAAAGCTCGTAAGGCAGACTTCGACGATGAAAAGGAC
AAAAAAAAGGATAATGACAAACACATAGATAAAAGACCAAAAAGCGGTCCTCGTTTGGAT
GAAAATGGCAATCCACTTCCCAAGGAGCCTCGTCTCCCAAAGAGAAAGGTGGCTGTTATG
GTTGGTTACTGTGGTACTGGCTACCATGGTATGCAATATAATCCACCAAATCCAACCATC
GAGTCTGCCCTATTCAAAGCATTTGTTGAAGCAGGTGCTATTTCCAAGGACAACTCCAAC
GATTTGAAAAAGAATGGATTCATGAGAGCTGCAAGAACTGATAAGGGTGTCCATGCTGGA
GGTAATTTAATATCATTGAAAATGATTATTGAAGATCCTGATATCAAGCAGAAGATCAAC
GAAAAGTTACCGGAAGGGATAAGGGTATGGGATATCGAGCGTGTGAACAAGGCGTTTGAT
TGTAGAAAAATGTGCAGTTCACGTTGGTACGAATACTTATTACCAACTTATTCACTCATT
GGCCCCAAACCTGGTTCTATACTTTATAGAGACATCGAAGAAAGTAAAACAGAATTACCT
GGTGTATTAGATGAAGATTTGGAATCCAAAGAATTTTGGGAAGAGTTTAAAAAAGATGCG
AATGAAAAATTTTCAACAGAAGAAATCGAAGCTATATTAGCATATGTTCCGCCCGCAAGA
GATGAATTTGATATAAATGAAGAACTATACCAGAAGGTAAAAAAGTACAAGCAATTAGAA
AATGCTCACCGTAGAAGATATCGTATATCCGCGGCAAAACTGGCCAAATTCCGTGCTTCT
ACAAGTCAATACCTTGGCGCTCATAACTTCCATAATTTTACATTAGGCAAGGACTTCAAA
GAACCAAGTGCCATTCGATTTATGAAAGATATAAAAGTATCTGATCCATTTGTTATTGGC
GATGCCCAAACAGAATGGATTTCCATCAAGATTCACGGCCAGTCTTTCATGCTACATCAA
ATTCGTAAGATGGTATCAATGGCAACCTTAATTACCCGTTGTGGTTGCCCCGTCGAACGC
ATTAGTCAGGCTTACGGACAGCAGAAGATTAATATTCCGAAGGCACCTGCATTAGGATTA
TTGTTAGAAGCTCCAGTATTTGAAGGTTATAATAAAAGACTAGAACAGTTTGGTTACAAG
GCGATCGATTTTTCCAAATATCAAGACGAAGTGGATAAGTTCAAAATGAAGCATATCTAC
GATAAGATCTACAAGGAAGAGGTGGACGAAAATGTTTTTAATGCGTTCTTTAGTTATATT
GATAGTTTCAACAAGGTTACTGGAGCACAGGGAGAAGAAACTGCCGATAAATCGGGACCT
GCTGTGCAAAAGAGTATCTTCGAATTCTTGACAGCTAAGGGTATCCCAGGTCTTACTGAT
GCGCCCGAGAGCAATAAGAAGATTAAGCAAAGAAAAAGAATGGAAGAGGAGGAAGCTGCT
AGTAAAAAGGCTGAAATATCCAGCACCACTCAGAGCAACGAACCTGAAGTACAACCGGAA
GCGGCAGCTAATTAG
Promoter Sequence
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>PUS1 YPL212C
TTTAAGCGCTAATTATATGATTCTTTATTATACAGAAAAAAATACATTGTGAGAGATAAC
GCAAGCTGTAAGTGAAATGTACACGGGAATTCATCATCAGTCCTTCCCACTAAGTAAACA
AGGTGTCTTCATCTCTCAAATACTCACCAATATCTGCTTGTCTGAAAGCAACTATACCAG
TGGGTTGCATGTTTCTTGACTCAGAAGTACTTTTCGCACTGACACCGAACCCTAATGGCA
CATCATTCATTGCAAACACAATAACACCGGCGTGTTCTGGTATATCATCAGACATTTTAC
CCACATGTGCCTTTAACACATGATTACCGTATAAGAATGGCATCTCCCCATTAGGTTTAA
TCCATATCTTATATTTGGCATGCTTAGCCAATACTGTCAAAGAAGTAATATGTAACCTGA
ATTTTCCAGTTTTCGTGAATTTACCTAAACAAATACCCAGAGACATCAAGTTAGGTCTTG
CTACACTAGTAGCCAATTTTGCAACATGATCGGGTACGTAATATACTCTATCCTTTTGTA
ATCTGAAGACATGAGGAAGTTCTTTATTATCCACTAAAAAAGAAATATTTCTACCAATAT
AGCCGGCGAGTTTTTCGAAAACAACCTTGGTCTCTTCTTCTGTTAGCTGTCTCATTATTG
CACCTAACTATAGTTTCCCTCAATGGTTCTACTACTCGGAAATCTAGAATACGATCCAAT
CACTAAACCGTCAATTACCTCAATAATACATTGCTTACTTTAGTTCTAAGCTCATCGCAT
ATTTCAAAAATTTTCATTACCGTACAGAGATATATTATTTTGATGCGGGTAACTATTAGC
CGCTGAAATAATATTTTCTTTTTTTTTTTTTCTTTTGGCTTTGAAATTTTTCACTTTTAG
TCATCGCTATAGTTCGAGAAATTTGAAATACAAGAAGTACTAAAAAAATAATAAAGGACA
ATAAAGTGCTAGTAAATAACAATTATAAGTGATATCAAGG
Chr coordinates
Chr XVI from 153149-151515