Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SAR1
Systematic Name
YPL218W
Strain
S288c
Description
ARF family GTPase; component of the COPII vesicle coat; required for transport vesicle formation during ER to Golgi protein transport; lowers membrane rigidity aiding vesicle formation; localizes to ER-mitochondrial contact sites where it enhances membrane curvature, thereby reducing contact size via its N-terminal amphipathic helix; regulates mitochondrial fission and fusion dynamics
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>SAR1 YPL218W
ATGGCTGGTTGGGATATTTTTGGTTGGTTCAGAGATGTGTTGGCTTCCCTTGGTCTGTGG
AACAAACATGGTAAACTACTTTTCTTGGGTTTGGATAATGCCGGTAAGACCACATTGCTA
CATATGTTAAAGAACGATAGATTGGCAACCTTACAACCAACATGGCATCCAACTTCTGAA
GAACTGGCTATTGGTAACATTAAGTTTACAACTTTCGATTTGGGTGGTCATATTCAAGCT
CGTCGTTTATGGAAGGATTATTTCCCAGAAGTTAATGGTATCGTCTTTTTAGTCGATGCT
GCTGACCCTGAAAGATTTGATGAAGCACGTGTCGAATTAGATGCTTTATTCAACATTGCC
GAATTGAAGGACGTTCCTTTTGTAATTCTTGGTAACAAGATCGATGCTCCAAACGCCGTT
TCTGAAGCGGAGCTACGTTCTGCTTTAGGATTATTGAATACCACTGGCTCTCAAAGAATT
GAAGGTCAAAGACCAGTTGAAGTTTTCATGTGTTCCGTTGTTATGAGAAATGGTTATTTA
GAGGCGTTCCAATGGTTATCTCAATATATTTAA
Promoter Sequence
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>SAR1 YPL218W
GAAGCACTATCTAAGTTCCGTGAGAATATCGAATTAATTTTACAACTATCTAAGAAAATT
AACGATAATGCGAACACTTTAGCGATTTCCTCCGAAGATCCTCAAAAATTTGTTAATTTT
GTGATGAAGAACCCACCTTCCTTATCATTCAGAGATTTTATCGACAGAATCCAGAATAAA
TGCATGTTTGGTGCCGTAGTCTATCTTGGAGCCACCTATCTACTTCAACTTGTGTTTCTT
ACGAGAGACGAAATGGACGGTCCCATAAAGTTGAAGGCTAAATTACAGGAGGACCAAGCC
CATAGGATCATCATATCTACAATAAGAATTGCCACCAAGCTATTAGAAGACTTTGTCCAC
TCACAAAACTACATTTGCAAAGTCTTCGGTATTTCAAAAAGACTGCTGACCAAACTGGAA
ATTTCTTTCATGGCGAGTGTTAATTTCGATGGATTAATGATTACTTGTGAAAAATTAGAA
AAAACATTGCATATCCTTGATGATACAAGACAGGCATTAGGAAACACATGAGTTTTGCAT
ATGTATTATGCAGGTTCATTTGTTCCTTCCCTTATTTCTTTTCATAGTATTTATTTTTAT
TTATTTATTTATTTTTTTTTGGATTTTATTTTATTTCTTTTTTAATGCTAAGAAAGTAAT
TCCGCATAATTAAACGTGTGCTGGCCTCGATAGGTACCTATAGTATACAGAAGCTTACGA
AAAGCTCCTGCAGGATGGCACTTCTAAAATTCGCGCTCAACATGGCCGTATTGTACATTA
TATCGTTCTATCATTATATCGTATACGCCCGCATTACCCGACAACTCCGTCTGCAACGCG
TTGACCAGAAAACTCGAACAAGAGATCGCATAAAAAACCAAAAGGAAACGAATTACTTGT
CAAATAGTTATTGTAATGGATCCTCTAGAAAGGCAAACAGTAGATTTATTTCCTTCTTTT
CTAGAAACATCATTATAACTAACAATATATAATTGGAATA
Chr coordinates
Chr XVI from 138698-138725,138865-139409