Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
MDL2
Systematic Name
YPL270W
Strain
S288c
Description
Mitochondrial inner membrane half-type ABC transporter; required for respiratory growth at high temperature; localizes to vacuole membrane in response to H2O2; similar to human TAP1 and TAP2 implicated in bare lymphocyte syndrome and Wegener-like granulomatosis
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>MDL2 YPL270W
ATGTTGAATGGTCGTTTACCACTTTTGCGGCTGGGCATATGCAGAAACATGCTGTCCCGT
CCCCGACTGGCTAAACTGCCATCTATAAGGTTTCGGTCTTTGGTCACCCCTTCTTCATCG
CAGCTCATTCCTCTCAGTCGGTTGTGTTTAAGGTCACCTGCAGTTGGAAAATCACTAATT
TTACAAAGTTTTAGATGTAATTCATCCAAAACAGTTCCAGAAACTTCTCTGCCTTCAGCC
TCTCCCATATCTAAAGGATCAGCAAGGTCGGCACATGCAAAGGAGCAATCTAAAACTGAT
GACTATAAAGATATAATAAGGTTATTTATGTTGGCGAAACGGGATTGGAAACTGCTTCTT
ACAGCCATACTTCTTTTAACCATATCATGTTCCATAGGCATGTCTATTCCTAAAGTCATA
GGTATTGTCCTTGACACACTTAAGACGTCATCTGGATCAGATTTTTTTGATTTGAAGATA
CCGATTTTTTCTTTGCCTTTATATGAGTTTCTTTCCTTTTTTACTGTTGCTTTACTGATT
GGTTGTGCTGCTAATTTTGGTAGATTTATATTATTGAGGATACTAAGTGAGCGTGTTGTT
GCACGCCTAAGGGCAAATGTCATTAAAAAAACGCTTCATCAAGACGCAGAATTCTTCGAC
AACCATAAAGTTGGGGATTTAATTTCTCGTTTAGGATCTGATGCTTATGTTGTTTCAAGA
TCAATGACCCAGAAGGTCTCGGATGGGGTCAAAGCCCTAATTTGTGGGGTTGTTGGCGTG
GGGATGATGTGTTCTTTGTCACCTCAACTATCAATATTGTTACTATTCTTCACTCCACCT
GTTCTTTTTAGTGCCTCAGTGTTCGGGAAGCAAATTAGAAACACCTCTAAAGACCTTCAA
GAAGCTACTGGTCAATTGACTAGAGTCGCTGAAGAACAACTCTCTGGTATCAAGACGGTT
CAGTCGTTTGTTGCTGAAGGTAATGAATTGTCTAGGTATAACGTTGCAATTAGAGATATT
TTTCAGGTGGGAAAAACTGCGGCATTTACAAACGCAAAGTTTTTTACTACAACTAGTCTC
TTAGGTGACCTAAGTTTTTTAACCGTCCTTGCGTATGGCTCCTATCTTGTTTTACAATCA
CAGCTCTCCATTGGTGATCTGACTGCATTTATGCTGTACACAGAATATACGGGGAATGCG
GTATTCGGCCTTTCTACCTTCTATTCGGAAATTATGCAGGGTGCTGGGGCCGCTTCCAGG
TTGTTTGAATTAACAGATAGGAAACCTTCCATTTCACCGACTGTGGGACACAAGTATAAA
CCAGATCGTGGTGTTATCGAATTTAAAGATGTTTCATTTAGCTACCCTACAAGGCCTTCT
GTTCAAATATTCAAGAATTTAAATTTTAAAATTGCGCCAGGATCGAGTGTTTGTATTGTG
GGCCCTTCAGGTCGTGGTAAATCTACAATTGCACTCTTACTGCTAAGATATTATAATCCC
ACTACTGGGACTATTACGATAGATAACCAAGATATCTCTAAATTGAATTGTAAATCCCTA
AGAAGGCATATTGGTATCGTTCAGCAAGAGCCGGTACTGATGTCAGGTACTATTAGGGAT
AATATCACTTATGGGTTGACATATACCCCAACAAAGGAAGAAATCAGGTCAGTAGCAAAG
CAGTGCTTTTGCCATAACTTTATCACAAAATTTCCGAACACATACGATACGGTAATTGGT
CCTCACGGCACCTTACTAAGTGGAGGACAAAAGCAGCGTATTGCGATTGCAAGGGCTCTA
ATCAAAAAGCCAACTATTTTGATTCTTGATGAAGCTACATCAGCTTTAGATGTTGAAAGT
GAAGGAGCCATTAACTATACGTTTGGTCAACTAATGAAATCAAAATCGATGACTATTGTT
AGCATCGCGCACAGGCTAAGTACGATCAGAAGATCAGAGAATGTTATTGTCCTTGGCCAT
GATGGATCAGTGGTAGAAATGGGCAAATTCAAAGAATTGTATGCGAATCCAACAAGTGCT
TTATCGCAATTACTTAATGAGAAAGCGGCTCCTGGGCCATCTGACCAACAACTGCAAATA
GAGAAGGTCATCGAAAAGGAAGATTTGAATGAGAGTAAGGAGCATGATGACCAGAAAAAG
GACGATAATGACGATAATGATAATAATCATGATAACGACAGCAATAACCAGTCTCCAGAG
ACGAAAGACAATAATTCAGATGATATTGAAAAATCTGTCGAACATCTCCTGAAAGACGCG
GCAAAGGAGGCTAATCCAATTAAGATCACACCACAACCGTGA
Promoter Sequence
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>MDL2 YPL270W
ATGCCTATCTGAATACAATTCTTCAACTCACATCAGTGGGACACTAAATAAAGCATATGG
TATGAAATACTATGAATTATTGAATTATTGGCAGACACAGCAGCGACAAGTCAGAGTGCT
TACAAAAAAAAAAGAGTTGATCCGGCTAAAGAAAGTCTGATTTACGTATTTATCCAGGTT
CAAACGGATTGCCAAAAATAGTCGATAACCTCGGAGTAAGCAAAGCAACAATATATTTGT
TCTTCGAAAAGGTAAACTTCTTAACTTCTATAGAAGCATTGTACTAGTTCTCTCGAAGAA
AAAAACTAAGAAAGCTATAGCTGTATCTTACCAAGCCATGAACTTGAGGAATTGGTAATC
CTTATTAGGAAATACGCTAAACTAGGTAATAGCAGATGATTTACTAGCTTACTATCTCAC
ACTAAGTCTGGCAACGCGCTTATTTTTTAATACTTTTATACGAACCAATGAAATTTGATC
CTCCCCTTTTTCGTCTAGTTAAATGAAGAGATACAAGTAGGCCTTTCTATTGAGTACTTA
GCAAGATATGTATTTCTAAGAAACATCAACAGTTTCAGCCCACAACCGATTCATAAAATG
TCTGCCTGGAGGAAAGCTGGTATATCATATGCTGCATATTTGAATGTGGCCGCTCAGGCT
ATCCGTTCTTCATTGAAAACTGAATTACAAACCGCTAGTGTTCTTAACAGATCGCAAACA
GATGCTTTTTATACCCAATATAAAAATGGCACTGCAGCTTCTGAACCCACTCCAATAACA
AAATAGTTTAACGCTTCCTGGGAACTGCAGCTCTTTTTTTACTCGCTGATATACATTTTA
AATATTCTAGCAACTGTGTATGAAAACTTACGTACTTTTATACGGGAAACTAATAATGAC
TACAATGATATTGAATACTGGCCGCTTCGAAGAGTGGTATAAAGTTTGTATCATTGCATT
AAAAGAAAAAGAAATATATGTCCCATCATCGCCAATCGCA
Chr coordinates
Chr XVI from 30482-32803