Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
NHP6A
Systematic Name
YPR052C
Strain
S288c
Description
High-mobility group (HMG) protein; binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to chromosomes; functionally redundant with Nhp6Bp; required for transcriptional initiation fidelity of some tRNA genes; homologous to mammalian HMGB1 and HMGB2; NHP6A has a paralog, NHP6B, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress
External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden
Promoter Sequence
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>NHP6A YPR052C
TCTACGGACTTACTATACGGTTGGTTGGAAAGAAGCAGCTCAGGCGCCCTATACCATCTT
GTAGCAACGTAGTTGGTTATATGGGGCTGCACAGTGGAATGACACTTGAAAAATCCGGCA
TGAATACCCCTAGCGAGACCAAAATCGCAGATCTTCAAACAGCCATTCAATGTGCACAAT
ATGTTCCCAGGCTTCAAATCTCGGTGGATGACATCTGCACTGTGTATGTACTTTAGCCCA
CACAGGATTTGGTAAAGAAAGTATTTGATATGAAACTCCGAGAGCTGCACGGACGAATGT
ATGACTTTTGCCAAATCATAATCAATCAGTTCCTGGTAGCAATACAGTCCGTCATAGGGC
GAGCTGGTCACTATCTCTAGATCGATTAGATTTACAATATTTTTATGGCCCTTGAAGAAG
TTCATGAATTTTAGCTCACGGATGGCCCTTTTCAAAAGGATCTCCTTATTAAAGATGTTG
CTGATCTTCTTTACCGCTATCCTAGCAGCTGGGCTTCGACCCTTAAACTTCACTGAGCAC
ACTGTCCCATAGGCTCCCTTGCCCAGGAATTGGATTATCTCGTAGTATCCTGGGATGGAT
ATTCTCTCCTTGGCAAAAATCGTCCTCTGTTGAGGAGCACCGAGGTTGGAGGCCACATTT
ATGGCTCTGGTATTATCTGTAAGTGTGCAATTCATTCTTGGAGCGTTGAGCACGTCTACA
TTTCTATCGATATGATGTATCGCACGACGTTAAATACTGTTCAAGTGTCACAAATTAGTG
GCGCCGAATTCTACCCTCACGCCTCGTCGCGCGCGATACTTTTCGAATCACCCGCCTTTT
GCCGCCTATTTTTTTCGCCGTTCGTTTATTTAGCGGTGGGCAAACAAACAACACAGTATT
TATTACTGGTACCGACTGTTAAAGAAGGACTGTTTTGGGACGTGTTTTTTTCCTGTTTTT
GCTCAATTGACTACCCTATACATAGTAAAGCACAGTCGCA
Chr coordinates
Chr XVI from 665974-665693