Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
ROX1
Systematic Name
YPR065W
Alias
REO1
Strain
S288c
Description
Heme-dependent repressor of hypoxic genes; mediates aerobic transcriptional repression of hypoxia induced genes such as COX5b and CYC7; repressor function regulated through decreased promoter occupancy in response to oxidative stress; contains an HMG domain that is responsible for DNA bending activity; involved in the hyperosmotic stress resistance
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>ROX1 YPR065W
ATGAATCCTAAATCCTCTACACCTAAGATTCCAAGACCCAAGAACGCATTTATTCTGTTC
AGACAGCACTACCACAGGATCTTAATAGACGAATGGACCGCTCAAGGTGTGGAAATACCC
CATAATTCAAACATTTCTAAAATTATTGGTACGAAGTGGAAGGGCTTACAACCGGAAGAT
AAGGCACACTGGGAAAATCTAGCGGAGAAGGAGAAACTAGAACATGAAAGGAAGTATCCT
GAATACAAATACAAGCCGGTAAGAAAGTCTAAGAAGAAGCAACTACTTTTGAAGGAAATC
GAGCAACAGCAGCAGCAACAACAGAAAGAACAGCAGCAGCAGAAACAGTCACAACCGCAA
TTACAACAGCCCTTTAACAACAATATAGTTCTTATGAAAAGAGCACATTCTCTTTCACCA
TCTTCCTCGGTGTCAAGCTCGAACAGCTATCAGTTCCAATTGAACAATGATCTTAAGAGG
TTGCCTATTCCTTCTGTTAATACTTCTAACTATATGGTCTCCAGATCTTTAAGTGGACTA
CCTTTGACGCATGATAAGACGGCAAGAGACCTACCACAGCTGTCATCTCAACTAAATTCT
ATTCCATATTACTCAGCTCCACACGACCCTTCAACGAGACATCATTACCTCAACGTCGCT
CAAGCTCAACCAAGGGCTAACTCGACCCCTCAATTGCCCTTTATTTCATCCATTATCAAC
AACAGCAGTCAAACACCGGTAACTACAACTACCACATCCACAACAACTGCGACATCTTCT
CCTGGGAAATTCTCCTCTTCTCCGAACTCCTCTGTACTGGAGAACAACAGATTAAACAGT
ATCAACAATTCAAATCAATATTTACCTCCCCCTCTATTACCTTCTCTGCAAGATTTTCAA
CTGGATCAGTACCAGCAGCTAAAGCAGATGGGACCAACTTATATTGTCAAACCACTGTCT
CACACCAGGAACAATCTATTGTCCACAACTACCCCTACGCATCATCACATTCCTCATATA
CCAAACCAAAACATTCCTCTACATCAAATTATAAACTCAAGCAACACTGAGGTCACCGCT
AAAACTAGCCTAGTTTCTCCGAAATGA
Promoter Sequence
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>ROX1 YPR065W
AGTTGACCTACATTCAACCTGCAAATATTGCTTTGCTTCAAGAAATGATTACACAGACGT
CTATTTTCTTCTACATAATGCACGAAACTTGGGCATTTAGTCATGTAGCCGCCTAGCGAG
CCTGGGTGCCGTCCTATCTCCTTTGTTCGTGCAAAGAGACAGGAACACACACTGCGTTCT
CTTGCGGCCGGTCTGGCGGACTCAGGGGTGCGGCGTTTGCTTAACCGGAGGGAATAATAA
AATCGGGGTGACGCAAGTATGAAGTCATGTGTGCTTAGCAATTACGTAGAGGGATTAGAA
ATAATAGTGTGCGGTTATCGGAACCGGCTCTTGTTCCCGTTTAGAGCAACCCAGGTGCAG
GCGTACTTTAAAGTATTTTCTTTCTTTTTTTTCCTGCTACTTACGCTAGGAGCTGCCGCA
GCTGCAAAGCCGACGTCGGAGAGGCAGGTGATCTTCGGCTCGGCCGACAAATCCCCTGGA
TATCATTGGCCTGTCGAGGTATCGGCCGCGTGGAACTACCGGGAATTACTATGCAAAACA
ATTGGAAATCTGGTAGGAAAACCTTGTTCTAGAACTTGGCGATTGCTGACAAAGAAGAAA
AGGGCCTATTGTTGCTGCCTCTTTTGTTGTTCTTCCTCGTATTGTCTTGCCGGTGTTCTT
TGTGTCTTTTGTGTGTAGGTTCTTACTATTATAGTGCTCTTTGCTATTATATTTTCTTCG
TTTTCACTTTGCGTAATGTAACGGTCTTAAACAAAGTTTTTTTTTTTTCGCTCTTGCATT
TTCCTTTTCTGCTCTATCTTATTTGCTAATTGTAGTTTCAGAAGTTTTACTTAAATATAG
CACTATTTTCCAGTTTTAATGTTTCTTCTCATTGCTTTCTTTTATAATTTTCGCATATAA
TTATACATTTACGGTGTCTTAACTCTCCCTCTTCACCCCTCATTATTCCAGAAAATACTA
ATACTTCTTCACACAAAAGAACGCAGTTAGACAATCAACA
Chr coordinates
Chr XVI from 679693-680799