Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
ISR1
Systematic Name
YPR106W
Strain
S288c
Description
Predicted protein kinase; negatively regulates the hexosamine biosynthetic pathway (HBP), which converts fructose-6-phosphate into UDP-N-acetylglucosamine, a precursor of chitin biosynthesis, GPI-anchor formation and glycosylation; interacts genetically with GFA1, encoding the first enzyme in the HBP; involved in Gfa1p phosphorylation (S332, T334); contains a Pho85p-regulated SCF-CDC4 phosphodegron; unstable, cell cycle regulated protein, peaking at G1/S
External sources
Open in SGD
Open in KEGG
Gene Sequence
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>ISR1 YPR106W
ATGAACAGTACACCTCCTACGTCACCCGTCACCAGGGTTTCTGATGGTTCCTTTCCATCC
ATAAGTAACAATAGTAAGGGTTTTGCTTATCGCCAACCGCAAAAACATAAAAGTAACTTC
GCATATTCACATCTGGTATCTCCTGTAGAGGAGCCGACAGCTAAATTCAGTGAGGCATTC
CAGACAGATTATTCTAGTAAGGCGCCCGTTGCTACCTCGGAGGCGCACCTAAAGAACGAT
TTAGACGTATTGTTCACTACCCCCCGGTTTTACTCTCCGGAGAATTTGGCTTTAATGTTC
CGTCTTTCTAATACAGTTTCTTCCCTAGAATTTCTGGATGAGTTTTTGATGGGCATATTA
CTTGCTCCAGAGATGGATTTTTTGTCAAATCCAAGTTATTCTCTTCCGTCTAACAAATTA
GTGGGACAGGGAAGTTATTCATATGTGTACCCTATATCATCAAGTGCTTCATCAAGATGT
AACAACGATTCAGGGGTTGTTTTAAAGTTTGCCAAATCACAGCATAAAAGCAAGGTGATT
TTACAGGAAGCTTTGACGCTAGCATATCTCCAGTACATGAGTCCTTCAACCAATGAAAGT
CATATTATTCCATTCTATGGGTTGACATACATAACTAAATCCCATTTTAGAAGACTGAGG
TCCAACGAATGTGTTCCTGGCCTTATTCTTCCGAAATGCGAAATGAGTTTATATCACTTC
AATACAGCAGTGTCACATAAGCTTTCGTTGATAACAAAAAGAAAAATATGGTGGAGACTT
ATGAAGCAAATGATAGACGCATTAAAATCTTTGAAAACAAATGGTATAATTCATGGTGAT
ATAAAAACAGCAAATATTTTAATAACAGAAATGCATGTTCTTAATGGAGGCCATTGTAAG
GATTTTGACTTCTACCTTGCTGACTTTACGTCGGCATTTCACATTAATCAAACACCAACA
GATCTGAATACCACGGTAGAATACTGTGCACCAGAACTAATTGATAGCTCCTCCGATCAT
GTTCCTACATTTGAATCGGATTTGTATGCCGTGGGGCTTTGTCTTTTATCATTTATATCG
CAGCATGAGCCTTACAACGAACTTCAGGCGTTAGTGTCGCATGGATCCTCTCCAGGTATT
GGCAGTTCATCTATACAGCAGTCCCAATGGCTGATAAATGCTCTTTTGAAAAAAGATCCT
ATAAATCTAAACATGTTAAGAAACGATTTATTCCAGGATTGGAAGTCAGAACTAGCATTA
TTGTCCAGAATTCTGGTTGATAGACTTCCTCTAGAAAATCTCATAACTATACTCGATAGT
AACTATATATGA
Promoter Sequence
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>ISR1 YPR106W
GATACAATAAGTTTTTTATCCGGAAGGCTTCTAATTTCATTGATTGCTGTCGCAGCAACT
AAGTAATCCTTTGTTTCTAAAGCAGAATGCGCCAGTGAAATATTATTCTTTAGCGTCCTG
ACGTCTTTTACAAATTGTAACGTTTTGTTGACCAAAGCGCGTTCCTGATCTACAGTTTCA
ATATCGTCATGTATAGCTTTTGCTCTTGCGTTCGAAGAAGAAATGGTGGCCACAGTCTCA
TGAAACTGAGTCAAAGTAGTCGTAAGGTTAGTTCTTTGCAATTCTAATTTCCGGGACTCT
TTGTTGAGCGATGATTGCGACTGTTGCACAAATGCATTTAATTGTTTAGATTGTTTTGCG
TAATCATTGGCTATCACTTCAGACAGCTTGTCTATTTGAGATAGTGTCGATAATTTGTCT
AATAACAAGGTGTACCTTGCTAGATTTTTAGACAATTGGCCCTCGATGATCGAGCTCTCC
CATGATGCATTCGATTTTTGCCCTTCCATCAAAACTTCACCCTTTTAGAGCCTGACAATA
CAGTATCGTTAGTTTGCGCTACTTCGCTGTCCCAACGAATTTGGTTTGTTTTCTATGTTC
TATCTCTATCCCACACTTTTTTCACAATTCCTTTACAGGCGAAAATTCAAAAAAGTGACG
TAAATGGAGTTCTAAAAGCTAAAGCAACAAGTTAATAAGGTTAGAAGATCGTAAATGTGT
TTCAAAAGTTGCTTACCTCCTTCACTATATCTCAGCTGCTTGTATAGCCTATGACGAAAA
TTTATGTTCCCTAGCAAGGATATAATGTGTCAATCAACATGATCGCAAACCAGCTAGATT
GTGATGTATGGGTCTATCTTATTGTTTATTTTGACTAGCATTGAATAAACAAAAAGCGCT
GCTAATAGATTCTTGCCTTTATATAACGGGGATCTAACCTCATCAACAGCAAAAATCGTC
TTAAAACACATCTCAAAGACTAGTTCTCAAACGTCACGCT
Chr coordinates
Chr XVI from 740061-741392