Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
PIN3 Systematic Name
YPR154W Alias
LSB2 Strain
S288c Description
Negative regulator of actin nucleation-promoting factor activity; interacts with Las17p, a homolog of human Wiskott-Aldrich Syndrome protein (WASP), via an N-terminal SH3 domain, and along with LSB1 cooperatively inhibits the nucleation of actin filaments; short-lived protein whose levels increase in response to thermal stress; induces the formation of the [PIN+] and [RNQ+] prions when overproduced; PIN3 has a paralog, LSB1, that arose from the whole genome duplication External sources
Open in SGD
Open in KEGG
Gene Sequence
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>PIN3 YPR154W
ATGTCTGCTTCATTGATTAATCGTTCCTTAACAAACATTAGGACAGAACTGGATTTTCTA
AAAGGGTCAAATGTCATTTCAAATGACGTTTACGATCAAATAAATAAGAGCTTGCCGGCA
AAATGGGATCCTGCCAATGCACCCCGCAACGCCAGTCCAGCTTCCTTGGAATATGTCGAA
GCTCTTTATCAATTTGATCCTCAACAAGATGGTGATTTGGGCTTAAAACCAGGTGACAAG
GTCCAACTTTTAGAAAAATTATCTCCAGAGTGGTACAAGGGTAGCTGTAATGGCCGTACC
GGTATTTTCCCAGCAAACTATGTCAAGCCAGCTTTCTCTGGGTCTAACGGTCCATCCAAT
CTTCCACCACCTCCACAGTATAAAGCTCAAGAATTACAACAAATCCCCACGCAAAATAGT
GCCGCATCATCTTATCAACAGCAGCCATTTCCTCCACCTTCCACAAATTATTATCAGCAG
CCTCAACAACAGCCGCAACAAGCTCCTCCTCCCCAACAACAACAACAACAACAACAACAT
CAGAGCTCACATAGCCACTTGAAGAGCTTTGGTAGCAAATTGGGTAATGCCGCCATTTTT
GGGGCAGGCGCTAGTATTGGGTCAGATATTGTTAATAATATCTTTTAA Promoter Sequence
Download FASTA
>PIN3 YPR154W
CGAAGAAAAAAAGAAACATACTGAAAGTTGATAAATATGCAATAATAAAACCTTTTCCTA
CTCTTGACGCTTCTGTATAAGATAAAAACTGCCAACAAGATCAGTTCCAACTTCCTGCCG
TATTATGAGGTATGTTATTCATTACCAAGACTATATCCGCCACGGCTGGATGCAGGCATC
GCTCCCTGTGGCTTAAGAAAATAATAGGCACAAAACTAACAATAAAAACATCCACTACTC
TGTCGCATGTTCCCTGTGCTCAGATCATTCGTAACAAATAACGATATACCTGTTGGATAT
GTAACGCCAAAATTCCCCTCATTATACTGGCCCATCAACAACTCGAAGTATAATACTGCA
TTCTTATACTATATATCTGACATTTGGAAATTTTCGCTGTACTGGACTTTGATCTTTAAT
GGTGCATTTTACGTTACTGCTGGTGTGTATGCTAGCTTGACCCATAGAAAGAAGGCTGGA
AGTGTATGGATATTCGTCATGTACGTCTTATACGGAGGCGTTCAAGGCTTGACGACTGGT
ACAGTTATGGGGTTTTTAATAGGTGCGATCTATAGATCTGGTTTATTTTCTATGTCTACA
TGGGTCCCACTTTGTTGCGCAGTAGTCCAAATCCTTTTCGATGTGGTGCTAAGTTATTCC
ATGGTTGGTTCCGTTATGTGAAAGCTTCTGTCAAGAAAAAACAAGAAGGGGTTTACTGAT
TTGATGATAAAAGTTAGCAGCAACTTTTGAATGAGAATGTGCCATCCTTCACGTAAAGAG
CCTAATACTCTTTCTTCAAAGCGCTAGATTGTTCTAAACGTTTCTTTAACTATTGTTTTC
GTTCGTGCAGCGTGATTAACCGAGCCTCCTTCGAGGCGGGGATGGATATTGTAAGCTGCA
TATATAGTCGAACCTCAAATCGGTTGAGACAATAGGCAAAGTGCCCACATTGGCGCAAAC
ACAAGAACATTAGGAAAGAAGGCAATCTGATATTTCAAAA
Chr coordinates
Chr XVI from 834565-835212
