Locus Information
Locus Info
Protein Info
GO Info
Orthologs
Standard Name
SKI3
Systematic Name
YPR189W
Alias
SKI5
Strain
S288c
Description
Ski complex component and TPR protein; mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay; mutations in the human ortholog, TTC37, causes Syndromic diarrhea/Trichohepatoenteric (SD/THE) syndrome
External sources
Open in SGD
Open in KEGG
Gene Sequence
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Sequence hidden
Promoter Sequence
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>SKI3 YPR189W
TAGAAGGTGAAACTGATCCATTGCGTATTGCCATGAAGGAGTTGGCTGAAAAGAAAATTC
CTTTGGTTATTAGAAGATATTTACCAGATGGTTCCTTTGAGGACTGGAGTGTGGAGGAAC
TCATTGTGGATTTGTGATTACACCTGCATTTTCCTTTATGTGTATTTGCTTTGTTTGTAT
ATTATTATAACTATAAAGAACGATTTATTTTGTAATGCAAATAACTGGACGAGAGAACCA
CGCTATAACCTATTTGGTAATAAAAATGTTTGTATGAATAAAAAAGCTGCTGACTGCTTT
CTTTGATATGTGTATATAGAATATTTAATCGGTGATTGAATCTAAGAAAAGCTTACCTCT
GAAAGTTCTCTCTTCGGTCGCTTGCTGATTTGTAGTAAACAATTTGAAAAGTTTAGCAAA
TTCTTCCTCAGGATTTTCAAAACCGGCTTCCTTTAAAGAATCAATGACCTCATTCAAGGG
AACGTTTAAATCGTGTCCTCTTCCAATGGCTTTTAAACTTTCTTCCAATTCTTCACGCTC
GGGAAACTGCGATAAGTTCTTCCCCATGATAGATAAGAATATGGGAAAGCTTACACCTTC
TTCTCCAACTTCCGCGGTACTGGTGTCATTGTCAGGTACCATTTTGGACCATTCCTCATC
TGTCAATGTCTTCCCCAATGTTGCATATATCTTGGTAAGATCTCCCCTACTAATCAGACC
ATCCTCATCCTCATCCAGCATTTGGAAAGCATCTTTGAGTTTATTTATGTAGTCCTGCGT
AAGTTGGTTAAACGTTAGCGATTCACTATGGTCCATATCTACTTCAAGTTTGCTCAATAA
ACGATTCGAAATTACTCTTTTCTTAGCTGTGCATTGTATAGTTTAGAAATACGAGAAATG
TAAAAAAAAAAATAAAGTTGGAAAACAACTAACTAATAAAACTTTCTTGTCAAGAAAGAC
ACTAAGAACACAGAAAAGAAACACGAAGAGCAGAGGAAAT
Chr coordinates
Chr XVI from 912664-916962