S.cerevisiae - Yeastract

Regulation Reference(s)

The Yeastract team, is actively curating each regulation evidence code, association type and environmental condition.

Transcription Factor	Target ORF/Genes	References	Evidence Code	Evidence Experiment	Association Type	Strain	Environmental Condition
Yap5p	YLR220W	PubMed Lee TI et al., Science, 2002 Oct 25;298(5594):799-804	Direct	Chip-on-chip	N/A	S288c	YPD medium; mid-log phase
		PubMed Li L et al., Mol Cell Biol, 2008 Feb;28(4):1326-37	Indirect	lacZ - wt vs TF mutant	Positive	S288c	Minimal medium; mid-log phase
		PubMed Pimentel C et al., PLoS One, 2012;7(5):e37434	Indirect	RT-PCR - wt vs TF mutant	Positive	BY4742	SC medium
			Indirect	RT-PCR - wt vs TF mutant	Positive	BY4742	20 min SC growth with 2 mM FeSO4
			Indirect	RT-PCR - wt vs TF mutant	Positive	BY4742	5 min SC growth with 2 mM FeSO4
			Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4742	20 min SC growth with 2 mM FeSO4
			Indirect	Microarray analysis - wt vs TF mutant	Positive	BY4742	60 min SC growth with 2 mM FeSO4
		PubMed Li L et al., J Biol Chem, 2012 Oct 12;287(42):35709-21	Indirect	lacZ - wt vs TF overexpression	Positive	S288c	Absence of methionine
			Indirect	lacZ - wt vs TF overexpression	Positive	S288c	YPD medium; mid-log phase
		PubMed Rietzschel N et al., Mol Cell Biol, 2015 Jan;35(2):370-8	Indirect	Luciferase - wt vs TF mutant	Positive	S288c	Yap5-Cterminal Myc-tag variants in which the cysteine residues of the n-CRD (N1 to N4) or the c-CRD (C1 to C3) were substituted by alanine (or serine in N4) either alone or in combination were expressed in DELTAyap5 cells. Transcriptional activities of the indicated full-length Yap5 variants were determined in DELTAyap5 cells harboring reporter plasmid pYRE-LUX (hybrid promoter that consists of the tw
		PubMed Rossi MJ et al., Nature, 2021 Apr;592(7853):309-314	Direct	ChIP-exo	N/A	BY4741	YPD medium, 25.C